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The map label for this gene is qorA [H]

Identifier: 170749371

GI number: 170749371

Start: 3121188

End: 3122201

Strand: Reverse

Name: qorA [H]

Synonym: Mrad2831_2964

Alternate gene names: 170749371

Gene position: 3122201-3121188 (Counterclockwise)

Preceding gene: 170749372

Following gene: 170749370

Centisome position: 51.37

GC content: 71.7

Gene sequence:

>1014_bases
ATGGCCACCACCGACCTGCCCGGGAGCATGCGCCAGATCCGCTACGCGGGGTCCGGTGGACCGGAGGTGATCAGCCTGGA
GACCGCGCCGGTGCCGAGCCCCGGGCCCGGTCAGGTCCTGATCGAGGTGGTGGCCGCCGGTGTGAACCGGCCCGACGTGG
CGCAGCGGTCGGGGGTGTACCCGCCGCCGCCCGGCGCCACCGAGATTCCCGGCCTCGAGGTCGCCGGCCGCGTGGTCGCG
CTCGGCAGCGGGGTCGAGAATCTGACGGAAGGGGACGAGGTCTGCGCCCTGGTGATCAGCGGCGGCTACGCCGAGTACGC
TGTGGCCGAGGCGGCCCACTGCCTGCCGCGGCCGAAGGCCGTCGCGCTGGTCGACGCCGGCGGCCTGCCGGAGACGTTCT
TCACGGTCTACTCCAACGTCGTGCAGCGCGGTCGCCTCGCGCGCGGCGAGAGTTTCCTCGTGCATGGCGGGTCGAGCGGC
ATCGGCGCCACGGCCATCCAGATCGCCAAGCACGTCGGCGCCCGGGTCTTCGCCACCGCCGGCTCGACCGAGAAGTGCCG
GTTCTGCGAGGATCTCGGCGCTGACGCCGCGATCGACTACAAGCAGGCGGATTTCGCCGAGGAGGTGAAGCGCCTCACCG
AAGGGCGCGGCGTCGACGTCATCCTCGACATGATCGGCGCGAGCTATCTCGCCCGGAACCTCAAGTCGCTGGCACCGGAC
GGCCGGCTGGTGATGATCGCCCTGATGGGCGGCTACAAGGTGGACGGGCTGAACATCACGCCGATCATGCGCAACCGGCT
GACCTTCACCGGCTCGACGCTGCGGCCGCGCGCGAAGGCCGACAAGGCCGCGATCGCCGACGGCCTGCGCCGGGACATCT
GGCCGGAGCTGGAGGCCGGACGCATCCGGTCCGTCACCCACGCCACGTTCCCGCTGGAGCGGGCGCGGGAGGCGCACGAG
CTGATGGAATCGAGCGCCCATCTCGGCAAGATCCTGCTGACGACCGGGCGCTAG

Upstream 100 bases:

>100_bases
GCGCGCGCGGCTTGCCAAGCGCGCCCGTTGCCGCAAGTAGAGCCGGACCGCGACACCGTGAGCGCGGCCGACACGACGTG
CGCGCGGAGGACAATCGCTG

Downstream 100 bases:

>100_bases
CGCCGGCCCCGGCAGGAACCCGCCTCGGCGGCCCCGCGTTGGCGGCCGGTAACGAGATCGTGTCGCACAGCGCCCGTTCC
GGCGTGTGGCGTCCCGCCGA

Product: PIG3 family NAD(P)H quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MATTDLPGSMRQIRYAGSGGPEVISLETAPVPSPGPGQVLIEVVAAGVNRPDVAQRSGVYPPPPGATEIPGLEVAGRVVA
LGSGVENLTEGDEVCALVISGGYAEYAVAEAAHCLPRPKAVALVDAGGLPETFFTVYSNVVQRGRLARGESFLVHGGSSG
IGATAIQIAKHVGARVFATAGSTEKCRFCEDLGADAAIDYKQADFAEEVKRLTEGRGVDVILDMIGASYLARNLKSLAPD
GRLVMIALMGGYKVDGLNITPIMRNRLTFTGSTLRPRAKADKAAIADGLRRDIWPELEAGRIRSVTHATFPLERAREAHE
LMESSAHLGKILLTTGR

Sequences:

>Translated_337_residues
MATTDLPGSMRQIRYAGSGGPEVISLETAPVPSPGPGQVLIEVVAAGVNRPDVAQRSGVYPPPPGATEIPGLEVAGRVVA
LGSGVENLTEGDEVCALVISGGYAEYAVAEAAHCLPRPKAVALVDAGGLPETFFTVYSNVVQRGRLARGESFLVHGGSSG
IGATAIQIAKHVGARVFATAGSTEKCRFCEDLGADAAIDYKQADFAEEVKRLTEGRGVDVILDMIGASYLARNLKSLAPD
GRLVMIALMGGYKVDGLNITPIMRNRLTFTGSTLRPRAKADKAAIADGLRRDIWPELEAGRIRSVTHATFPLERAREAHE
LMESSAHLGKILLTTGR
>Mature_336_residues
ATTDLPGSMRQIRYAGSGGPEVISLETAPVPSPGPGQVLIEVVAAGVNRPDVAQRSGVYPPPPGATEIPGLEVAGRVVAL
GSGVENLTEGDEVCALVISGGYAEYAVAEAAHCLPRPKAVALVDAGGLPETFFTVYSNVVQRGRLARGESFLVHGGSSGI
GATAIQIAKHVGARVFATAGSTEKCRFCEDLGADAAIDYKQADFAEEVKRLTEGRGVDVILDMIGASYLARNLKSLAPDG
RLVMIALMGGYKVDGLNITPIMRNRLTFTGSTLRPRAKADKAAIADGLRRDIWPELEAGRIRSVTHATFPLERAREAHEL
MESSAHLGKILLTTGR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=36.890243902439, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=36.890243902439, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=31.8042813455657, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=31.8042813455657, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI18379349, Length=343, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=29.0519877675841, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI24308257, Length=341, Percent_Identity=27.5659824046921, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI41872631, Length=312, Percent_Identity=27.2435897435897, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI28557745, Length=230, Percent_Identity=32.6086956521739, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI47519420, Length=343, Percent_Identity=28.8629737609329, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI197927207, Length=186, Percent_Identity=29.0322580645161, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1790485, Length=333, Percent_Identity=30.3303303303303, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI226510941, Length=328, Percent_Identity=26.219512195122, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082125, Length=354, Percent_Identity=27.683615819209, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=334, Percent_Identity=27.2455089820359, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI212642053, Length=311, Percent_Identity=27.0096463022508, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=247, Percent_Identity=31.9838056680162, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=225, Percent_Identity=28, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=342, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323961, Length=363, Percent_Identity=24.2424242424242, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=365, Percent_Identity=22.7397260273973, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=363, Percent_Identity=23.4159779614325, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330659, Length=276, Percent_Identity=26.8115942028986, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920632, Length=276, Percent_Identity=26.8115942028986, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24581345, Length=340, Percent_Identity=25.8823529411765, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35423; Mature: 35292

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTDLPGSMRQIRYAGSGGPEVISLETAPVPSPGPGQVLIEVVAAGVNRPDVAQRSGVY
CCCCCCCCHHHHEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCC
PPPPGATEIPGLEVAGRVVALGSGVENLTEGDEVCALVISGGYAEYAVAEAAHCLPRPKA
CCCCCCCCCCCHHHCCEEEEECCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCE
VALVDAGGLPETFFTVYSNVVQRGRLARGESFLVHGGSSGIGATAIQIAKHVGARVFATA
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEC
GSTEKCRFCEDLGADAAIDYKQADFAEEVKRLTEGRGVDVILDMIGASYLARNLKSLAPD
CCCCHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
GRLVMIALMGGYKVDGLNITPIMRNRLTFTGSTLRPRAKADKAAIADGLRRDIWPELEAG
CCEEEEEEECCEEECCEEECHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
RIRSVTHATFPLERAREAHELMESSAHLGKILLTTGR
CCHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEECCC
>Mature Secondary Structure 
ATTDLPGSMRQIRYAGSGGPEVISLETAPVPSPGPGQVLIEVVAAGVNRPDVAQRSGVY
CCCCCCCHHHHEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCC
PPPPGATEIPGLEVAGRVVALGSGVENLTEGDEVCALVISGGYAEYAVAEAAHCLPRPKA
CCCCCCCCCCCHHHCCEEEEECCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCE
VALVDAGGLPETFFTVYSNVVQRGRLARGESFLVHGGSSGIGATAIQIAKHVGARVFATA
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEC
GSTEKCRFCEDLGADAAIDYKQADFAEEVKRLTEGRGVDVILDMIGASYLARNLKSLAPD
CCCCHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
GRLVMIALMGGYKVDGLNITPIMRNRLTFTGSTLRPRAKADKAAIADGLRRDIWPELEAG
CCEEEEEEECCEEECCEEECHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
RIRSVTHATFPLERAREAHELMESSAHLGKILLTTGR
CCHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]