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The map label for this gene is mdtA [H]

Identifier: 170749263

GI number: 170749263

Start: 3008914

End: 3010167

Strand: Reverse

Name: mdtA [H]

Synonym: Mrad2831_2856

Alternate gene names: 170749263

Gene position: 3010167-3008914 (Counterclockwise)

Preceding gene: 170749266

Following gene: 170749262

Centisome position: 49.53

GC content: 71.93

Gene sequence:

>1254_bases
ATGCTGAGTGAGGACGTGCACGGCCGCGACGGGTCTCGCGCGGACGAGACGGTCGCGGACCGGAGCCACGGCGACGCGCC
ACGCGCCGTCGCCGGACCAGCGAAGAAGCGCTCCGGCGCGGCCGGGCTGATCCTCCTGCTGCTCGCCGTCGCGGGCGGCG
GCGCCTACGGCTACACGCGCCTGAATCAGCCCGCGGTGAAGTCCAGGGCGGCGGCCCCGCTGCCGGTGCCCGTCACCCTC
GGCACGGTCGAGCAGGGGCCGTTCGCCCTCGTGTCGAACGGCCTCGGCACCGTCCAGGCGTACAACACCGTCCAGGTGCG
CACGCGCGTCGACGGCGAGATCCAGCAGGTCGCGTTCCGCGAGGGGCAGACCGTCCGCAAGGGCGACGTGCTCGTGCAGA
TCGACCCGCGGCCCTACCAGGCGGCGCTGGATCAGGCGAAGGCCAAGAAGGAGCAGGACACGGCCAACCTCGGCAACGCG
AAGGCGGACCTCGTCCGCTACACCGGGCTGGGCGCCTTCGCCTCCCGGCAGCAGACCGAGACGCAGACGGCCCTGGTCGC
CCAGCTCACCGCGCAGGTGGCGTCCGACCAGGCGGCCATCGACAACGCCACGACGCAGCTCGGCTACGCCACGATCCGCG
CGCCCATCGACGGCGTCACGGGCTTCCGGCAGGTCGATATCGGCAACATCGTCAACGCGGCCGGTCAGACCCCGATCGTG
ACGATCACCCAGGTCGAGCCGATCTTCGTGGTGTTCACGGCCCCGGAGGATCAACTGCCCGCCATCACCGCGGCCCTCAA
GGCCGGTGACGTGCCGGTGGAGGCCTGGACGTCGGACGGGCTGACCAAGCTCGCCGACGGCAAGCTCGCCCTGTTCAACA
ACCAGGTCGACACCGCGACCGGCACGATCCGCCTCAAGGCCGTCTACGAGAACAGGAACCACGCGCTGTGGCCGGGCCTG
TCGGTTTCCACCAAGATGCGGGTCGGCACGGTCGCGGTCGCCACGACGGTGCCGGACGACGCGATCCAGCACGGGCCCGA
CGGGCTGTTCGCCTTCGTGGTCGACGATGCCAGCCGGGCGCATCAGCGCGCGCTGAAGGCGGGCCGCTCGGATTCGGGGC
GGACGCGCGTTCTCAGCGGCGACCTCCGGCCCGGCGAGCGGGTGATCGTCGCCGGCCAGTACAAGGTGCAGGACGGCAGC
CTCGTGGCCGATCCGCACAGCGCGCACACCGCGCAGGCGGAGGCGGTCCAGTGA

Upstream 100 bases:

>100_bases
CCGCGGGGTCCCGCGATGTCCGGCGCGGTCATTGTATGCTATTGAATGCAAAATTATCCCGGTCCGCGAAGCGGTCGGAT
CAACGGGCGGATACCGGCGC

Downstream 100 bases:

>100_bases
CGCGCGCGGCACGTCTCACGGCGGCCGTGTCAGCGCGCGGGGTCCGAGCATGAAGGGCGGCATCTCGGCCCCGTTCATCC
GGTTTCCGGTGGCAACCACG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLSEDVHGRDGSRADETVADRSHGDAPRAVAGPAKKRSGAAGLILLLLAVAGGGAYGYTRLNQPAVKSRAAAPLPVPVTL
GTVEQGPFALVSNGLGTVQAYNTVQVRTRVDGEIQQVAFREGQTVRKGDVLVQIDPRPYQAALDQAKAKKEQDTANLGNA
KADLVRYTGLGAFASRQQTETQTALVAQLTAQVASDQAAIDNATTQLGYATIRAPIDGVTGFRQVDIGNIVNAAGQTPIV
TITQVEPIFVVFTAPEDQLPAITAALKAGDVPVEAWTSDGLTKLADGKLALFNNQVDTATGTIRLKAVYENRNHALWPGL
SVSTKMRVGTVAVATTVPDDAIQHGPDGLFAFVVDDASRAHQRALKAGRSDSGRTRVLSGDLRPGERVIVAGQYKVQDGS
LVADPHSAHTAQAEAVQ

Sequences:

>Translated_417_residues
MLSEDVHGRDGSRADETVADRSHGDAPRAVAGPAKKRSGAAGLILLLLAVAGGGAYGYTRLNQPAVKSRAAAPLPVPVTL
GTVEQGPFALVSNGLGTVQAYNTVQVRTRVDGEIQQVAFREGQTVRKGDVLVQIDPRPYQAALDQAKAKKEQDTANLGNA
KADLVRYTGLGAFASRQQTETQTALVAQLTAQVASDQAAIDNATTQLGYATIRAPIDGVTGFRQVDIGNIVNAAGQTPIV
TITQVEPIFVVFTAPEDQLPAITAALKAGDVPVEAWTSDGLTKLADGKLALFNNQVDTATGTIRLKAVYENRNHALWPGL
SVSTKMRVGTVAVATTVPDDAIQHGPDGLFAFVVDDASRAHQRALKAGRSDSGRTRVLSGDLRPGERVIVAGQYKVQDGS
LVADPHSAHTAQAEAVQ
>Mature_417_residues
MLSEDVHGRDGSRADETVADRSHGDAPRAVAGPAKKRSGAAGLILLLLAVAGGGAYGYTRLNQPAVKSRAAAPLPVPVTL
GTVEQGPFALVSNGLGTVQAYNTVQVRTRVDGEIQQVAFREGQTVRKGDVLVQIDPRPYQAALDQAKAKKEQDTANLGNA
KADLVRYTGLGAFASRQQTETQTALVAQLTAQVASDQAAIDNATTQLGYATIRAPIDGVTGFRQVDIGNIVNAAGQTPIV
TITQVEPIFVVFTAPEDQLPAITAALKAGDVPVEAWTSDGLTKLADGKLALFNNQVDTATGTIRLKAVYENRNHALWPGL
SVSTKMRVGTVAVATTVPDDAIQHGPDGLFAFVVDDASRAHQRALKAGRSDSGRTRVLSGDLRPGERVIVAGQYKVQDGS
LVADPHSAHTAQAEAVQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=327, Percent_Identity=38.5321100917431, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1789929, Length=339, Percent_Identity=29.2035398230088, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789665, Length=335, Percent_Identity=29.8507462686567, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786668, Length=328, Percent_Identity=30.1829268292683, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43685; Mature: 43685

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEDVHGRDGSRADETVADRSHGDAPRAVAGPAKKRSGAAGLILLLLAVAGGGAYGYTR
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCCCC
LNQPAVKSRAAAPLPVPVTLGTVEQGPFALVSNGLGTVQAYNTVQVRTRVDGEIQQVAFR
CCCCHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCEEEEEEEEEEEEECCCHHHHHHHH
EGQTVRKGDVLVQIDPRPYQAALDQAKAKKEQDTANLGNAKADLVRYTGLGAFASRQQTE
CCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCHHHHCHHHH
TQTALVAQLTAQVASDQAAIDNATTQLGYATIRAPIDGVTGFRQVDIGNIVNAAGQTPIV
HHHHHHHHHHHHHHCCHHHHCCCHHHCCEEEEECCCCCCCCCEEECHHHHHHCCCCCCEE
TITQVEPIFVVFTAPEDQLPAITAALKAGDVPVEAWTSDGLTKLADGKLALFNNQVDTAT
EEEEECEEEEEEECCCCCCCHHHHHHHCCCCCEEEECCCCCHHHCCCEEEEECCCCCCCC
GTIRLKAVYENRNHALWPGLSVSTKMRVGTVAVATTVPDDAIQHGPDGLFAFVVDDASRA
CEEEEEEEEECCCCEECCCCCCCCEEEEEEEEEEECCCHHHHHCCCCCEEEEEECCHHHH
HQRALKAGRSDSGRTRVLSGDLRPGERVIVAGQYKVQDGSLVADPHSAHTAQAEAVQ
HHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCEEECCCCCCCCHHHCCC
>Mature Secondary Structure
MLSEDVHGRDGSRADETVADRSHGDAPRAVAGPAKKRSGAAGLILLLLAVAGGGAYGYTR
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCCCC
LNQPAVKSRAAAPLPVPVTLGTVEQGPFALVSNGLGTVQAYNTVQVRTRVDGEIQQVAFR
CCCCHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCEEEEEEEEEEEEECCCHHHHHHHH
EGQTVRKGDVLVQIDPRPYQAALDQAKAKKEQDTANLGNAKADLVRYTGLGAFASRQQTE
CCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCHHHHCHHHH
TQTALVAQLTAQVASDQAAIDNATTQLGYATIRAPIDGVTGFRQVDIGNIVNAAGQTPIV
HHHHHHHHHHHHHHCCHHHHCCCHHHCCEEEEECCCCCCCCCEEECHHHHHHCCCCCCEE
TITQVEPIFVVFTAPEDQLPAITAALKAGDVPVEAWTSDGLTKLADGKLALFNNQVDTAT
EEEEECEEEEEEECCCCCCCHHHHHHHCCCCCEEEECCCCCHHHCCCEEEEECCCCCCCC
GTIRLKAVYENRNHALWPGLSVSTKMRVGTVAVATTVPDDAIQHGPDGLFAFVVDDASRA
CEEEEEEEEECCCCEECCCCCCCCEEEEEEEEEEECCCHHHHHCCCCCEEEEEECCHHHH
HQRALKAGRSDSGRTRVLSGDLRPGERVIVAGQYKVQDGSLVADPHSAHTAQAEAVQ
HHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCEEECCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA