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The map label for this gene is argS

Identifier: 170749174

GI number: 170749174

Start: 2904025

End: 2905776

Strand: Reverse

Name: argS

Synonym: Mrad2831_2767

Alternate gene names: 170749174

Gene position: 2905776-2904025 (Counterclockwise)

Preceding gene: 170749176

Following gene: 170749173

Centisome position: 47.81

GC content: 70.03

Gene sequence:

>1752_bases
ATGAACATCTTCGCCCTGTTCGAGGCGCGCGTGCGCGACGCCGTGGAGGCGCTGACCCGCGCCGGCCACCTGCCCGAGGG
CCTCGACCTGGGCCGCGTGGTGGTCGAGCCGCCCCGCGACGCCTCGCACGGCGACCTCGCCACGAACGCCGCCCTGGTCC
TTGCCAAGGAGGCGCGGGCCAACCCGAAGGCGCTGGGCGAGTCCCTGGCGGCCGAGCTCCGCGCGGATCCGCGGATCGTC
GAGGCGAGCGTCGCCGGGCCGGGCTTCATCAATCTCCGGCTCGACCCCGCGATCTTCCACGCGGTCGTACGCGACGCCCT
GGAGGCCCCGGAGGCGTTCGGCCGCGCGCGGCTGCCCGGCGGCCCGATCAACGTCGAGTACGTGTCGGCGAACCCGACGG
GGCCGATGCATGTCGGCCACGGCCGGGGCGCGGTGTTCGGCGACGCCCTGTGCAACCTGCTCGTCGCGGCCGGCCGGCAG
GTGACGCGCGAATACTACATCAACGATGCCGGCGTTCAGGTCGATGTGCTGGCCCGCTCGGCCTTCCAGCGCTACCGCGA
GGCCCTCGGCGAGCCCTTCGCCATCGCGGAGGGCCTCTATCCGGGCGACTACCTGAAGCCCGTGGGCGCCCGGCTGGCCG
AGACGCACGGCCGCGCGCTCCTCGACAAGCCCGAGGCGGAGTGGCTGCCCACGGTGCGCGAGACCGCGCTCGGCATGATG
ATGGACATGATCCGGGCCGACCTGGCGGCGATCGGCATCCGCCACGACGTCTTCTTCTCCGAGCGCACGCTTCAGGAGAG
CGGGGCCGTGAAGGCCCTGCTCGCGGAGCTGCGCGCCAAGGGCCTCGTCTACGAGGGTCGCCTTCCGCCGCCCAAGGGGC
AGCTGCCGGAGGACTGGGAGGACCGCGAGCAGACGCTGTTTCGCACCAAGGAATTCGGCGACGACAGCGACCGGCCGCTG
CTGAAGTCGGACGGCTCGTACACGTATTTCGCCTCCGACATCGCCTACCACCGCGCCAAGTACCTCGCCGGCGCGACCGA
GCTGATCGACGTCCTCGGCGCCGATCACGGCGGCTACGTGAAGCGCATGCAGGCCGCCGTGAAGGCGGTCAGCGACGGCA
AGGCCACGCTCGACGTCAAGCTCTGCCAGCTGGTGCGGCTGTTGCGCGCAGGCGAGCCGGTCAAGATGTCGAAGCGGGCC
GGCGAGTTCGTGACCCTGCGCGACGTGATCGACGAGGTCGGCCGCGACGCGATCCGGTTCATGATGCTCTACCGGAAGAA
CGACGCAACCCTGGATTTCGACCTCGCCAAAGTGGTGGAACAGTCGAAGGACAATCCGGTCTTCTACGTCCAGTACGCCC
ATGCCCGCGTCCGCTCGGTGCAGCGGCAGGCCCGCGAGGCGTTCCCGGACGCCGACCTCTCGGTCGCCGCGCTGGCCCGC
GAGGCGGACCTCGCCGTGCTGAGCGACCCGGGCGAGATCGAGATGATGCGCCTCATCGCGCAGTACCCGCGGGTCCTCGA
ATCCGCGGCGCTGGCGCACGAGCCGCACAGGATCGCCTTCCACCTCTATGAACTGGCCTCCGCGCTGCATAGTTTCTGGA
ACAAGGGCAAAGACTTGCCGCAATTACGGTTTGTTAATGCAACCGACCGAAAGTCGACGTGGGCCCGGCTGGCGCTCGTC
GAAGCTCTGCGGAGCACGCTGGCGGCCGGCCTTGCGATTCTCGGTGTGACCGCGCCGGACGAGATGCGATAG

Upstream 100 bases:

>100_bases
GGCGCCGTGACACCCTCCCGCCCCCTTGCTAGACCGCCGGGGCGGGCGCCGGCCGGACGGGCCGGGCGACGAGACCCCCG
CGCGAGCGAGATCGAGACCC

Downstream 100 bases:

>100_bases
GCCCGAGTGCATCGGGCCGGTCTTCGGCGTTGATGTGAGGATGCTGCCATGACGAACGCTTCGCGCGCTCAGGTCGATTT
GGACGCCCTCGCGCGCGATC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MNIFALFEARVRDAVEALTRAGHLPEGLDLGRVVVEPPRDASHGDLATNAALVLAKEARANPKALGESLAAELRADPRIV
EASVAGPGFINLRLDPAIFHAVVRDALEAPEAFGRARLPGGPINVEYVSANPTGPMHVGHGRGAVFGDALCNLLVAAGRQ
VTREYYINDAGVQVDVLARSAFQRYREALGEPFAIAEGLYPGDYLKPVGARLAETHGRALLDKPEAEWLPTVRETALGMM
MDMIRADLAAIGIRHDVFFSERTLQESGAVKALLAELRAKGLVYEGRLPPPKGQLPEDWEDREQTLFRTKEFGDDSDRPL
LKSDGSYTYFASDIAYHRAKYLAGATELIDVLGADHGGYVKRMQAAVKAVSDGKATLDVKLCQLVRLLRAGEPVKMSKRA
GEFVTLRDVIDEVGRDAIRFMMLYRKNDATLDFDLAKVVEQSKDNPVFYVQYAHARVRSVQRQAREAFPDADLSVAALAR
EADLAVLSDPGEIEMMRLIAQYPRVLESAALAHEPHRIAFHLYELASALHSFWNKGKDLPQLRFVNATDRKSTWARLALV
EALRSTLAAGLAILGVTAPDEMR

Sequences:

>Translated_583_residues
MNIFALFEARVRDAVEALTRAGHLPEGLDLGRVVVEPPRDASHGDLATNAALVLAKEARANPKALGESLAAELRADPRIV
EASVAGPGFINLRLDPAIFHAVVRDALEAPEAFGRARLPGGPINVEYVSANPTGPMHVGHGRGAVFGDALCNLLVAAGRQ
VTREYYINDAGVQVDVLARSAFQRYREALGEPFAIAEGLYPGDYLKPVGARLAETHGRALLDKPEAEWLPTVRETALGMM
MDMIRADLAAIGIRHDVFFSERTLQESGAVKALLAELRAKGLVYEGRLPPPKGQLPEDWEDREQTLFRTKEFGDDSDRPL
LKSDGSYTYFASDIAYHRAKYLAGATELIDVLGADHGGYVKRMQAAVKAVSDGKATLDVKLCQLVRLLRAGEPVKMSKRA
GEFVTLRDVIDEVGRDAIRFMMLYRKNDATLDFDLAKVVEQSKDNPVFYVQYAHARVRSVQRQAREAFPDADLSVAALAR
EADLAVLSDPGEIEMMRLIAQYPRVLESAALAHEPHRIAFHLYELASALHSFWNKGKDLPQLRFVNATDRKSTWARLALV
EALRSTLAAGLAILGVTAPDEMR
>Mature_583_residues
MNIFALFEARVRDAVEALTRAGHLPEGLDLGRVVVEPPRDASHGDLATNAALVLAKEARANPKALGESLAAELRADPRIV
EASVAGPGFINLRLDPAIFHAVVRDALEAPEAFGRARLPGGPINVEYVSANPTGPMHVGHGRGAVFGDALCNLLVAAGRQ
VTREYYINDAGVQVDVLARSAFQRYREALGEPFAIAEGLYPGDYLKPVGARLAETHGRALLDKPEAEWLPTVRETALGMM
MDMIRADLAAIGIRHDVFFSERTLQESGAVKALLAELRAKGLVYEGRLPPPKGQLPEDWEDREQTLFRTKEFGDDSDRPL
LKSDGSYTYFASDIAYHRAKYLAGATELIDVLGADHGGYVKRMQAAVKAVSDGKATLDVKLCQLVRLLRAGEPVKMSKRA
GEFVTLRDVIDEVGRDAIRFMMLYRKNDATLDFDLAKVVEQSKDNPVFYVQYAHARVRSVQRQAREAFPDADLSVAALAR
EADLAVLSDPGEIEMMRLIAQYPRVLESAALAHEPHRIAFHLYELASALHSFWNKGKDLPQLRFVNATDRKSTWARLALV
EALRSTLAAGLAILGVTAPDEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=154, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1788184, Length=633, Percent_Identity=25.2764612954186, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985061, Length=194, Percent_Identity=28.8659793814433, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71985068, Length=194, Percent_Identity=28.8659793814433, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=25, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321883, Length=614, Percent_Identity=23.9413680781759, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_METRJ (B1M335)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001755434.1
- ProteinModelPortal:   B1M335
- GeneID:   6138810
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_2767
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63928; Mature: 63928

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFALFEARVRDAVEALTRAGHLPEGLDLGRVVVEPPRDASHGDLATNAALVLAKEARA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHCHHEEEEHHHCC
NPKALGESLAAELRADPRIVEASVAGPGFINLRLDPAIFHAVVRDALEAPEAFGRARLPG
CHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHCHHHHCCCCCCC
GPINVEYVSANPTGPMHVGHGRGAVFGDALCNLLVAAGRQVTREYYINDAGVQVDVLARS
CCCEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHH
AFQRYREALGEPFAIAEGLYPGDYLKPVGARLAETHGRALLDKPEAEWLPTVRETALGMM
HHHHHHHHCCCCEEHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHHCCHHHHHHHHHH
MDMIRADLAAIGIRHDVFFSERTLQESGAVKALLAELRAKGLVYEGRLPPPKGQLPEDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHH
DREQTLFRTKEFGDDSDRPLLKSDGSYTYFASDIAYHRAKYLAGATELIDVLGADHGGYV
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KRMQAAVKAVSDGKATLDVKLCQLVRLLRAGEPVKMSKRAGEFVTLRDVIDEVGRDAIRF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCEEEHHHHHHHHHHHHHHH
MMLYRKNDATLDFDLAKVVEQSKDNPVFYVQYAHARVRSVQRQAREAFPDADLSVAALAR
HHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EADLAVLSDPGEIEMMRLIAQYPRVLESAALAHEPHRIAFHLYELASALHSFWNKGKDLP
HCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
QLRFVNATDRKSTWARLALVEALRSTLAAGLAILGVTAPDEMR
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MNIFALFEARVRDAVEALTRAGHLPEGLDLGRVVVEPPRDASHGDLATNAALVLAKEARA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHCHHEEEEHHHCC
NPKALGESLAAELRADPRIVEASVAGPGFINLRLDPAIFHAVVRDALEAPEAFGRARLPG
CHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHCHHHHCCCCCCC
GPINVEYVSANPTGPMHVGHGRGAVFGDALCNLLVAAGRQVTREYYINDAGVQVDVLARS
CCCEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHH
AFQRYREALGEPFAIAEGLYPGDYLKPVGARLAETHGRALLDKPEAEWLPTVRETALGMM
HHHHHHHHCCCCEEHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHHCCHHHHHHHHHH
MDMIRADLAAIGIRHDVFFSERTLQESGAVKALLAELRAKGLVYEGRLPPPKGQLPEDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHH
DREQTLFRTKEFGDDSDRPLLKSDGSYTYFASDIAYHRAKYLAGATELIDVLGADHGGYV
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KRMQAAVKAVSDGKATLDVKLCQLVRLLRAGEPVKMSKRAGEFVTLRDVIDEVGRDAIRF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCEEEHHHHHHHHHHHHHHH
MMLYRKNDATLDFDLAKVVEQSKDNPVFYVQYAHARVRSVQRQAREAFPDADLSVAALAR
HHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EADLAVLSDPGEIEMMRLIAQYPRVLESAALAHEPHRIAFHLYELASALHSFWNKGKDLP
HCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
QLRFVNATDRKSTWARLALVEALRSTLAAGLAILGVTAPDEMR
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA