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The map label for this gene is aroC [H]

Identifier: 170749164

GI number: 170749164

Start: 2894317

End: 2895417

Strand: Reverse

Name: aroC [H]

Synonym: Mrad2831_2757

Alternate gene names: 170749164

Gene position: 2895417-2894317 (Counterclockwise)

Preceding gene: 170749165

Following gene: 170749163

Centisome position: 47.64

GC content: 71.3

Gene sequence:

>1101_bases
ATGTCGCACAACACCTTCGGCCACCTGTTCCGCGTCACGACCTTCGGCGAGAGCCACGGAGTCGCGCTCGGCTGCGTCGT
CGACGGCTGCCCCCCAGGCCTGCCCCTGGAGGCCGAGGAGATCCAGGCCGAGCTGGATCGCCGGAAGCCCGGCCAGTCGC
GCTTCACGACCCAGCGCCGCGAACCCGATCAGGTGAAGATCCTGTCCGGCGTGTTCGCGGACGACCGCACCGGCGGCCGC
CAGCTCACCACCGGCACGCCGATCGCGCTGATGATCGAGAACACGGATCAGCGCTCGAAGGACTATTCGGAGATCCGCGA
CAGCTACCGTCCCGGCCACGCCGACTACACCTACGACGTGAAGTACGGCATCCGTGACTATCGCGGCGGCGGCCGGTCCT
CGGCGCGGGAGACCGCCGCGCGGGTCGCGGCCGGCGCCGTGGCGCGCAAGGTCATCCCGGGCGTGACCATCCGGGCGGCC
CTGGTGCAGATGGGCCCGCACGCCATCGACCGATCCCGCTGGGACTGGGACGCGGTCGGCAACAACCCGTTCTTCTGCCC
CGATGCCGAGAGGGCTTCCTTCTACGAGACCTATCTCGACGGGCTCCGGAAGGACGGCTCGTCGGTCGGCGCCGTCATCG
AGGTCGTGGCCGAGGGCGTGCCGCCCGGCCTCGGCGCGCCGGTCTACGGCAAGCTGGACGCGGACCTCGCCGCCGCGATG
ATGTCGATCAACGCCGTGAAGGGCGTGGAGATCGGCGACGGCTTCGCCGCGGCAACCCTGCGCGGCGAGGACAACGCGGA
CGAGATGCGCGCCGGGAACGGCGGCCGGCCGCGCTTCCTGGCGAACCACGCGGGCGGCATCCTGGGCGGCATCTCCAACG
GCGAGCCGGTCGTGGTGCGCTTCGCCGTCAAGCCGACCTCCTCGATCCTGACGCCGCGCCGCTCGGTCACGCGCGACGGC
GCCGAGGTGGATCTCGTCACCAAGGGCCGGCACGATCCCTGTGTCGGCATCCGCGCCGTGCCGGTCGCGGAGGCCATGAT
GGCCTGCGTGCTGGCCGATCACTATCTGCGCCATCGCGGACAGACAGCGGGTGGAGGCTGA

Upstream 100 bases:

>100_bases
CGGCCCGTCGCCGAGCGCGGCAGCCTTCGCGCGTCTGCCCGGCCGCCCTGCACGGACCGCGTTTGTGCCCCCGGCGCTCC
CGCGCTAAGGCAGCCGCGCC

Downstream 100 bases:

>100_bases
AATGAACAGTGCGTTATACAAGACACCCGCTATCTCGCCTTCGTTGATTGATTCTTACGAGCGCGACGCAAAGGTTCTGG
CCAGCTACGAGTCGCCTGAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSHNTFGHLFRVTTFGESHGVALGCVVDGCPPGLPLEAEEIQAELDRRKPGQSRFTTQRREPDQVKILSGVFADDRTGGR
QLTTGTPIALMIENTDQRSKDYSEIRDSYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAVARKVIPGVTIRAA
LVQMGPHAIDRSRWDWDAVGNNPFFCPDAERASFYETYLDGLRKDGSSVGAVIEVVAEGVPPGLGAPVYGKLDADLAAAM
MSINAVKGVEIGDGFAAATLRGEDNADEMRAGNGGRPRFLANHAGGILGGISNGEPVVVRFAVKPTSSILTPRRSVTRDG
AEVDLVTKGRHDPCVGIRAVPVAEAMMACVLADHYLRHRGQTAGGG

Sequences:

>Translated_366_residues
MSHNTFGHLFRVTTFGESHGVALGCVVDGCPPGLPLEAEEIQAELDRRKPGQSRFTTQRREPDQVKILSGVFADDRTGGR
QLTTGTPIALMIENTDQRSKDYSEIRDSYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAVARKVIPGVTIRAA
LVQMGPHAIDRSRWDWDAVGNNPFFCPDAERASFYETYLDGLRKDGSSVGAVIEVVAEGVPPGLGAPVYGKLDADLAAAM
MSINAVKGVEIGDGFAAATLRGEDNADEMRAGNGGRPRFLANHAGGILGGISNGEPVVVRFAVKPTSSILTPRRSVTRDG
AEVDLVTKGRHDPCVGIRAVPVAEAMMACVLADHYLRHRGQTAGGG
>Mature_365_residues
SHNTFGHLFRVTTFGESHGVALGCVVDGCPPGLPLEAEEIQAELDRRKPGQSRFTTQRREPDQVKILSGVFADDRTGGRQ
LTTGTPIALMIENTDQRSKDYSEIRDSYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAVARKVIPGVTIRAAL
VQMGPHAIDRSRWDWDAVGNNPFFCPDAERASFYETYLDGLRKDGSSVGAVIEVVAEGVPPGLGAPVYGKLDADLAAAMM
SINAVKGVEIGDGFAAATLRGEDNADEMRAGNGGRPRFLANHAGGILGGISNGEPVVVRFAVKPTSSILTPRRSVTRDGA
EVDLVTKGRHDPCVGIRAVPVAEAMMACVLADHYLRHRGQTAGGG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=366, Percent_Identity=61.4754098360656, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321290, Length=376, Percent_Identity=43.6170212765958, Blast_Score=286, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39031; Mature: 38900

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTFGESHGVALGCVVDGCPPGLPLEAEEIQAELDRRKPGQSRFTTQRR
CCCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCC
EPDQVKILSGVFADDRTGGRQLTTGTPIALMIENTDQRSKDYSEIRDSYRPGHADYTYDV
CCCCEEEEHHCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEE
KYGIRDYRGGGRSSARETAARVAAGAVARKVIPGVTIRAALVQMGPHAIDRSRWDWDAVG
EECCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCCCCCC
NNPFFCPDAERASFYETYLDGLRKDGSSVGAVIEVVAEGVPPGLGAPVYGKLDADLAAAM
CCCEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
MSINAVKGVEIGDGFAAATLRGEDNADEMRAGNGGRPRFLANHAGGILGGISNGEPVVVR
HHHHHHCCCEECCCEEEEEECCCCCHHHHHCCCCCCCCEEECCCCCEEECCCCCCEEEEE
FAVKPTSSILTPRRSVTRDGAEVDLVTKGRHDPCVGIRAVPVAEAMMACVLADHYLRHRG
EEECCCHHHCCCCHHHCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCC
QTAGGG
CCCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTFGESHGVALGCVVDGCPPGLPLEAEEIQAELDRRKPGQSRFTTQRR
CCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCC
EPDQVKILSGVFADDRTGGRQLTTGTPIALMIENTDQRSKDYSEIRDSYRPGHADYTYDV
CCCCEEEEHHCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEE
KYGIRDYRGGGRSSARETAARVAAGAVARKVIPGVTIRAALVQMGPHAIDRSRWDWDAVG
EECCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCCCCCC
NNPFFCPDAERASFYETYLDGLRKDGSSVGAVIEVVAEGVPPGLGAPVYGKLDADLAAAM
CCCEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
MSINAVKGVEIGDGFAAATLRGEDNADEMRAGNGGRPRFLANHAGGILGGISNGEPVVVR
HHHHHHCCCEECCCEEEEEECCCCCHHHHHCCCCCCCCEEECCCCCEEECCCCCCEEEEE
FAVKPTSSILTPRRSVTRDGAEVDLVTKGRHDPCVGIRAVPVAEAMMACVLADHYLRHRG
EEECCCHHHCCCCHHHCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCC
QTAGGG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA