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The map label for this gene is rpiA

Identifier: 170749106

GI number: 170749106

Start: 2844561

End: 2845274

Strand: Reverse

Name: rpiA

Synonym: Mrad2831_2699

Alternate gene names: 170749106

Gene position: 2845274-2844561 (Counterclockwise)

Preceding gene: 170749107

Following gene: 170749105

Centisome position: 46.81

GC content: 76.33

Gene sequence:

>714_bases
GTGAGCGGGCCGGACCTGCGGCGGGCCGCGGCCGCCCGCGCCCTCGACCTCGTCGAGCCGGGCATGCGGCTCGGCCTCGG
CACGGGCTCCACGGCGGCGGCCTTCGTGGCGCTCCTCGGCGAGCGCGTCCGTGCCGGCCTCGACATCGTCGGCGTACCGA
CCTCCGAGGCCACGCGCGCGCAGGCCGAGAGCCTGGGCATCCGCCTCGCGACCCTGGACGAGCAGCCCGAGCTCGACCTG
ACCATCGACGGCGCCGACGAGGTCGACGACCGGCTCCGCCTGATCAAGGGCGGCGGCGCGGCGCTCCTGCGCGAGAAGAT
CGTCGCCTGCGCGAGCCGCCGCATGGTGGTGATCGCCGACGCGGCCAAGCACGTGGCGCGGCTCGGCGCCTTCCCGCTCC
CGGTCGAGGTCAATCCCTTCGGCCTCAAGGCCACGCACCGCGCCGTCGAGGCGGCGGTCGCGGGGGCCGGCTGCTCCGGT
GACGTCCGGCTGCGCGCCCAGGCCGATGGCAAGCCCCTGGTCACGGACGGGGGCCATTACATCCTCGACGCGCGCCTCGG
TGCGATTCCCGATCCGGAGGCCCTCGGCGCCGCCCTCTGGGCCGTGCCGGGCGTCGTCGAGCACGGCCTGTTCCTCGGCA
TCGCCGACGCCGCGATCCTGGCGGCGGCGCGGGACGGGCAGGCCGAGGTCACCGTTCTCGGCAGCCTCACCTGA

Upstream 100 bases:

>100_bases
GGCCCGGTCCCGTGCTACGGGCCGCCCGACGCTCACGGAAAGACCGGCTGCCCATGACCCGCGCTCCCTCGCTCACCCTC
GCCGACCGGGCGGTGTCCCG

Downstream 100 bases:

>100_bases
GGCGCCGCCCTCCATCGCCGGCCATCCTCGCAAGAAAGTCCAGCATGTCCCGTCGTCCCACCGCCGTGCCAGGCCTCCTC
AGCCTCGCGCTCGGCCTCGC

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSGPDLRRAAAARALDLVEPGMRLGLGTGSTAAAFVALLGERVRAGLDIVGVPTSEATRAQAESLGIRLATLDEQPELDL
TIDGADEVDDRLRLIKGGGAALLREKIVACASRRMVVIADAAKHVARLGAFPLPVEVNPFGLKATHRAVEAAVAGAGCSG
DVRLRAQADGKPLVTDGGHYILDARLGAIPDPEALGAALWAVPGVVEHGLFLGIADAAILAAARDGQAEVTVLGSLT

Sequences:

>Translated_237_residues
MSGPDLRRAAAARALDLVEPGMRLGLGTGSTAAAFVALLGERVRAGLDIVGVPTSEATRAQAESLGIRLATLDEQPELDL
TIDGADEVDDRLRLIKGGGAALLREKIVACASRRMVVIADAAKHVARLGAFPLPVEVNPFGLKATHRAVEAAVAGAGCSG
DVRLRAQADGKPLVTDGGHYILDARLGAIPDPEALGAALWAVPGVVEHGLFLGIADAAILAAARDGQAEVTVLGSLT
>Mature_236_residues
SGPDLRRAAAARALDLVEPGMRLGLGTGSTAAAFVALLGERVRAGLDIVGVPTSEATRAQAESLGIRLATLDEQPELDLT
IDGADEVDDRLRLIKGGGAALLREKIVACASRRMVVIADAAKHVARLGAFPLPVEVNPFGLKATHRAVEAAVAGAGCSGD
VRLRAQADGKPLVTDGGHYILDARLGAIPDPEALGAALWAVPGVVEHGLFLGIADAAILAAARDGQAEVTVLGSLT

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=212, Percent_Identity=39.622641509434, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1789280, Length=212, Percent_Identity=41.5094339622642, Blast_Score=140, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17551758, Length=231, Percent_Identity=38.5281385281385, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6324669, Length=240, Percent_Identity=31.6666666666667, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281364072, Length=209, Percent_Identity=35.8851674641148, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_METRJ (B1M272)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001755366.1
- ProteinModelPortal:   B1M272
- SMR:   B1M272
- GeneID:   6138742
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_2699
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   CLSK2331068
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24181; Mature: 24050

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPDLRRAAAARALDLVEPGMRLGLGTGSTAAAFVALLGERVRAGLDIVGVPTSEATRA
CCCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHH
QAESLGIRLATLDEQPELDLTIDGADEVDDRLRLIKGGGAALLREKIVACASRRMVVIAD
HHHHHCEEEEECCCCCCEEEEECCCCCHHHHHEEEECCCHHHHHHHHHHHHCCCEEEEEH
AAKHVARLGAFPLPVEVNPFGLKATHRAVEAAVAGAGCSGDVRLRAQADGKPLVTDGGHY
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCE
ILDARLGAIPDPEALGAALWAVPGVVEHGLFLGIADAAILAAARDGQAEVTVLGSLT
EEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure 
SGPDLRRAAAARALDLVEPGMRLGLGTGSTAAAFVALLGERVRAGLDIVGVPTSEATRA
CCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHH
QAESLGIRLATLDEQPELDLTIDGADEVDDRLRLIKGGGAALLREKIVACASRRMVVIAD
HHHHHCEEEEECCCCCCEEEEECCCCCHHHHHEEEECCCHHHHHHHHHHHHCCCEEEEEH
AAKHVARLGAFPLPVEVNPFGLKATHRAVEAAVAGAGCSGDVRLRAQADGKPLVTDGGHY
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCE
ILDARLGAIPDPEALGAALWAVPGVVEHGLFLGIADAAILAAARDGQAEVTVLGSLT
EEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA