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The map label for this gene is ackA [H]

Identifier: 170749019

GI number: 170749019

Start: 2768763

End: 2769878

Strand: Reverse

Name: ackA [H]

Synonym: Mrad2831_2610

Alternate gene names: 170749019

Gene position: 2769878-2768763 (Counterclockwise)

Preceding gene: 170749020

Following gene: 170749011

Centisome position: 45.57

GC content: 72.22

Gene sequence:

>1116_bases
ATGATCCTCGTCCTCAACGCCGGATCGTCCAGCCTGCGTTGCGCCCTGTTCCGGCCCGGCGTCGACGCACCGGTCTGGCG
CGCCCACGTCGCCGGCACCGGGACGGACCCGAAGCTGTCGGTAGATGGCGAGCCGGTGGTCGGCGAACTACCACCGCAGG
GTGACCACGCGACCGTCGCCCGCTGGCTATTCGAGCGACTGCCCTACAAGCCGATGGCGGCCGGCCACCGCGTCGTCCAT
GGCGGCCTGCGCCACGCGGCGCCGGTCCGTCTCGATGCGGACGTCATGGTCACGTTGGAGGGACTGGTGCCGCTCGCACC
GGCGCACCAGCCGCAGGCTCTGGCCTGCATCCGGGCGGTCGGGGAGACGTGGCCGCACCTGCCGCAGGTCGCCTGCTTCG
ACACGGCCTTCCACAGGACGCAGGATCGGCCGGCCCAACTCTACCCGCTGCCGCGCGCCCTCATCGACGAGGGGCTGGTG
CGCTTCGGCTTCCACGGGCTGTCCTACGCTCATCTCGCCCGAAGCTACCCGACAGGGCGGGTACTGGCCGCCCATCTCGG
GCACGGGGCGAGCCTGTGCGCGATCCGGGACGGGCGCAGCGTCGCCACGACGATGGGTTTCACCACGCTCGACGGGCTGA
TGATGGGCACCCGCAGCGGGGCCGTCGACCCCGGCCTCGTGCTGCACCTGATCCGCGAGCGTGGCCTGTCGCCCGACGCG
GTGGCCGAGCTCCTGAACGAGCGGTCGGGCCTTCTCGGCGTCTCCGGCATCAGCGACGACGTGCGGGTCCTGGAGGCGAG
CGATGCGCCGGGAGCGCGTGAGGCCCTTGACCTGTTCGCTTACCGGATCGTGCGGGAAGCGGGCTCGCTCATCGCCGCAC
TCGGCGGGGTCGACGCCCTCGTCTTCACCGGCGGCATCGGCGAGCATGCCGCGCAGGTCCGCGTCGGGGTCTGTCGCGGG
CTTGCATTCGCGGGCGTCGCGCTCGACGACGTGGCCAATGCCGGCGGCGAGGCGAGGATCGAGGCGCCCGGCTCGGCGGT
CACGATCCGAATCGCGCCCGCGAACGAGGAGCGCGAGATCGCCCTGTCGATGACCGAAGCGCTCGCCCTGACGTGA

Upstream 100 bases:

>100_bases
GATCGAGGGCGACATCATGCAGTGCGGCCCGACCGACGCGGACGGGCCCGGCCGGTCGGGGACCGTGGACGGTTGTACGG
TTGTCACCTGAGGCCGCACG

Downstream 100 bases:

>100_bases
GCGCGCCTGTCGCCGAACAAGCCACTGCGAGACTTCCCGGTCAGGGCGCCGGTCGTTCGAGCTGCAGGTAAGCGGGATCG
AACTCGGCGACCTCGGCCAG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MILVLNAGSSSLRCALFRPGVDAPVWRAHVAGTGTDPKLSVDGEPVVGELPPQGDHATVARWLFERLPYKPMAAGHRVVH
GGLRHAAPVRLDADVMVTLEGLVPLAPAHQPQALACIRAVGETWPHLPQVACFDTAFHRTQDRPAQLYPLPRALIDEGLV
RFGFHGLSYAHLARSYPTGRVLAAHLGHGASLCAIRDGRSVATTMGFTTLDGLMMGTRSGAVDPGLVLHLIRERGLSPDA
VAELLNERSGLLGVSGISDDVRVLEASDAPGAREALDLFAYRIVREAGSLIAALGGVDALVFTGGIGEHAAQVRVGVCRG
LAFAGVALDDVANAGGEARIEAPGSAVTIRIAPANEEREIALSMTEALALT

Sequences:

>Translated_371_residues
MILVLNAGSSSLRCALFRPGVDAPVWRAHVAGTGTDPKLSVDGEPVVGELPPQGDHATVARWLFERLPYKPMAAGHRVVH
GGLRHAAPVRLDADVMVTLEGLVPLAPAHQPQALACIRAVGETWPHLPQVACFDTAFHRTQDRPAQLYPLPRALIDEGLV
RFGFHGLSYAHLARSYPTGRVLAAHLGHGASLCAIRDGRSVATTMGFTTLDGLMMGTRSGAVDPGLVLHLIRERGLSPDA
VAELLNERSGLLGVSGISDDVRVLEASDAPGAREALDLFAYRIVREAGSLIAALGGVDALVFTGGIGEHAAQVRVGVCRG
LAFAGVALDDVANAGGEARIEAPGSAVTIRIAPANEEREIALSMTEALALT
>Mature_371_residues
MILVLNAGSSSLRCALFRPGVDAPVWRAHVAGTGTDPKLSVDGEPVVGELPPQGDHATVARWLFERLPYKPMAAGHRVVH
GGLRHAAPVRLDADVMVTLEGLVPLAPAHQPQALACIRAVGETWPHLPQVACFDTAFHRTQDRPAQLYPLPRALIDEGLV
RFGFHGLSYAHLARSYPTGRVLAAHLGHGASLCAIRDGRSVATTMGFTTLDGLMMGTRSGAVDPGLVLHLIRERGLSPDA
VAELLNERSGLLGVSGISDDVRVLEASDAPGAREALDLFAYRIVREAGSLIAALGGVDALVFTGGIGEHAAQVRVGVCRG
LAFAGVALDDVANAGGEARIEAPGSAVTIRIAPANEEREIALSMTEALALT

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=387, Percent_Identity=36.1757105943152, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1788633, Length=393, Percent_Identity=35.3689567430025, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 38884; Mature: 38884

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLNAGSSSLRCALFRPGVDAPVWRAHVAGTGTDPKLSVDGEPVVGELPPQGDHATVA
CEEEEECCCCCEEEEEECCCCCCCHHEEEECCCCCCCEEECCCCCCCCCCCCCCCHHHHH
RWLFERLPYKPMAAGHRVVHGGLRHAAPVRLDADVMVTLEGLVPLAPAHQPQALACIRAV
HHHHHHCCCCCCCCCCHHHHCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHH
GETWPHLPQVACFDTAFHRTQDRPAQLYPLPRALIDEGLVRFGFHGLSYAHLARSYPTGR
HHCCCCCCCHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
VLAAHLGHGASLCAIRDGRSVATTMGFTTLDGLMMGTRSGAVDPGLVLHLIRERGLSPDA
CCEECCCCCCEEEEEECCCCEEHHHCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHH
VAELLNERSGLLGVSGISDDVRVLEASDAPGAREALDLFAYRIVREAGSLIAALGGVDAL
HHHHHHHCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VFTGGIGEHAAQVRVGVCRGLAFAGVALDDVANAGGEARIEAPGSAVTIRIAPANEEREI
EEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCEE
ALSMTEALALT
EEEHHHHHHCC
>Mature Secondary Structure
MILVLNAGSSSLRCALFRPGVDAPVWRAHVAGTGTDPKLSVDGEPVVGELPPQGDHATVA
CEEEEECCCCCEEEEEECCCCCCCHHEEEECCCCCCCEEECCCCCCCCCCCCCCCHHHHH
RWLFERLPYKPMAAGHRVVHGGLRHAAPVRLDADVMVTLEGLVPLAPAHQPQALACIRAV
HHHHHHCCCCCCCCCCHHHHCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHH
GETWPHLPQVACFDTAFHRTQDRPAQLYPLPRALIDEGLVRFGFHGLSYAHLARSYPTGR
HHCCCCCCCHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
VLAAHLGHGASLCAIRDGRSVATTMGFTTLDGLMMGTRSGAVDPGLVLHLIRERGLSPDA
CCEECCCCCCEEEEEECCCCEEHHHCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHH
VAELLNERSGLLGVSGISDDVRVLEASDAPGAREALDLFAYRIVREAGSLIAALGGVDAL
HHHHHHHCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VFTGGIGEHAAQVRVGVCRGLAFAGVALDDVANAGGEARIEAPGSAVTIRIAPANEEREI
EEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCEE
ALSMTEALALT
EEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA