| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is penA [H]
Identifier: 170748781
GI number: 170748781
Start: 2502445
End: 2504337
Strand: Reverse
Name: penA [H]
Synonym: Mrad2831_2363
Alternate gene names: 170748781
Gene position: 2504337-2502445 (Counterclockwise)
Preceding gene: 170748782
Following gene: 170748780
Centisome position: 41.2
GC content: 68.62
Gene sequence:
>1893_bases GTGTCCGATGACGCCGACCAGACCCTAGACCCGGCGGTCGAGCCCGCCGTGTCGGACCACGAGGCGGGGCTGCTCGAAGC CGCCGCGCTGGCGCATGCCGCCGGCGCGCCACGCCCCCTGGAAGAGGAGGCGCGCGTGCCCGAGCCGCGCGCCGAGCGCG CCAAGGCGCTCCTGCGCAGCATGTTCCGGCTGGCGATCGAGCGCTCGCACATGCGCGTCGCGATGGTCGGGCTGGTCTTC GTCGGCGTGTTCGGGACGATCTCGGCCAAACTCCTGATGATGGCGATCTTCGGGGAGCCGCCCAGCCAGGAGCACCGGGT CGCGGCGGCGTCCTCGACCGCCTTCCGGCCCGACATCATCGACCGCAACGGCGAGATCCTGGCCACCGACATCCGTACGG TCTCGGTCTTCGCCGAGCCGGGCAACATCTACGACAAGGACGAGGCGGTCGAGCTGCTCACCGCCGTCCTGCCGGAACTC AACGCGTCCGAGCTGCGCGCGAAGCTGACGCAACGCAAGGACAAGAAGGGCGCGGGCTTCGTCTGGGTGAAGCGCGAGCT CACGCCGAAGCAGCAGGCCGAGGTTCACCGGCTCGGCATCCCGGGTATCGGCTTCCTGCCCGACCACAAGCGGGTCTACC CGAACGGCGTCGCCGCCGCCCACATCCTGGGCGCGACGAACCTCGACGGCGTCGGCATCGCCGGCATGGAGAAGTACATC GACTCCACCGGCCTGCAGGCCCTCAACAGCTTCGGGCTGATCAACAAGCAGGCCGACCTGAAGCCGGTGCAGCTGTCGAT CGACCTGCGGGCGCAGTTCGCCGTGCGCGACGAGCTGGCCTGGGGCATCGACCACTTCAAGGCCAAGGCCGGCGCCTCGA TGATCCTCGACGTGAAGACCGGCGAAGTCATCGCCCTCGTCTCCATGCCGGATTTCGACCCGAACGATCCGAAGGACGCG CTCTCGCCCGACCGGATCAACCGGATGAATGTCGGCGTCTACGAGATGGGCTCGACCTTCAAGGCGATGACCCTCGCCAT GGCGCTCGATTCGGGCAAGTACAACGTCAACTCGACCTTCGACACCCGGGGCGGCGTGCTGAACTGGGGCCGGCAGAAGA TCCACGAGTACCACGGCACCAACCGCGTCATCACCATGCCGGAGGTCTTCACGCACTCCTCCAACATCGGCTCCGCCAAG ATGGCGCTCGGCGTCGGCGTGCCCGGCCACAAGGCCTTCCTGAAGAAGATGGGCCTGCTCGACCGGCTGCGCACCGAGCT GCCCGAGAGCGCGGCGCCGATCGTCCCGTCGCGCTGGACCGAGATCAACACCATCACCATCGCGTTCGGCCACGGCATCG CGGTGGCGCCGATCCAGGCGGCGGCCGCGGTGGCGGCCATCGCCAACGGCGGCGACCTGATGACGCCGACCTTCCTCAAG ACGACGCCCGAGGCGGCGAAGGCCCGCGCCGCGCACGTGCTCTCCGGCCAGACCTCCGAGGCGATGCGCTACATCATGCG GCTCAACGCCTCCGAGGGGTCGGCCAAGAAGGCGGCGATCCCGTACTACTTCGTCGGCGGCAAGACCGGCACCGCCGAGA AGGTCATCGGCGGCCGCTACATCCACAACCGCCTGTTCACGACCTTCATGGCGGCCGCGCCGATGAACGATCCGAAGTAC CTGTTCGTCACGATCATGGACGAGCCGCAGGGCCTGCCGGAATCGGGCGGCTACGCCACGGCGGCCTGGAATTCCGGCGT GGTGACCGGCAAGGTGATCGAGCGCGTGGCGCCGATCCTCGGCCTGCCGCCGCAATTCGAGCCGCCGGTGAGGCCGTTCC CGCAGATGGTCAAGCTCAATGCCTACCACGTCAACCAGCTCGGCGGCCCGTGA
Upstream 100 bases:
>100_bases GCCCAAGGACAAGGGTGCGATCGAGCCGCGCACGACCGGTTCGATCACCCGCACCGTCACCACGACCCGCACCCCGACGA CGGCTTCGAGGTAAATCCCC
Downstream 100 bases:
>100_bases GATTGGATCGATGAGGGTGGATCGATGAGCGCGCGGCTCGCCGACCTCTTCCCCGAGGCCGCCGGCCCCGCCGCGGACCT GACCGTCTCGGACCTCACGG
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: PBP-2 [H]
Number of amino acids: Translated: 630; Mature: 629
Protein sequence:
>630_residues MSDDADQTLDPAVEPAVSDHEAGLLEAAALAHAAGAPRPLEEEARVPEPRAERAKALLRSMFRLAIERSHMRVAMVGLVF VGVFGTISAKLLMMAIFGEPPSQEHRVAAASSTAFRPDIIDRNGEILATDIRTVSVFAEPGNIYDKDEAVELLTAVLPEL NASELRAKLTQRKDKKGAGFVWVKRELTPKQQAEVHRLGIPGIGFLPDHKRVYPNGVAAAHILGATNLDGVGIAGMEKYI DSTGLQALNSFGLINKQADLKPVQLSIDLRAQFAVRDELAWGIDHFKAKAGASMILDVKTGEVIALVSMPDFDPNDPKDA LSPDRINRMNVGVYEMGSTFKAMTLAMALDSGKYNVNSTFDTRGGVLNWGRQKIHEYHGTNRVITMPEVFTHSSNIGSAK MALGVGVPGHKAFLKKMGLLDRLRTELPESAAPIVPSRWTEINTITIAFGHGIAVAPIQAAAAVAAIANGGDLMTPTFLK TTPEAAKARAAHVLSGQTSEAMRYIMRLNASEGSAKKAAIPYYFVGGKTGTAEKVIGGRYIHNRLFTTFMAAAPMNDPKY LFVTIMDEPQGLPESGGYATAAWNSGVVTGKVIERVAPILGLPPQFEPPVRPFPQMVKLNAYHVNQLGGP
Sequences:
>Translated_630_residues MSDDADQTLDPAVEPAVSDHEAGLLEAAALAHAAGAPRPLEEEARVPEPRAERAKALLRSMFRLAIERSHMRVAMVGLVF VGVFGTISAKLLMMAIFGEPPSQEHRVAAASSTAFRPDIIDRNGEILATDIRTVSVFAEPGNIYDKDEAVELLTAVLPEL NASELRAKLTQRKDKKGAGFVWVKRELTPKQQAEVHRLGIPGIGFLPDHKRVYPNGVAAAHILGATNLDGVGIAGMEKYI DSTGLQALNSFGLINKQADLKPVQLSIDLRAQFAVRDELAWGIDHFKAKAGASMILDVKTGEVIALVSMPDFDPNDPKDA LSPDRINRMNVGVYEMGSTFKAMTLAMALDSGKYNVNSTFDTRGGVLNWGRQKIHEYHGTNRVITMPEVFTHSSNIGSAK MALGVGVPGHKAFLKKMGLLDRLRTELPESAAPIVPSRWTEINTITIAFGHGIAVAPIQAAAAVAAIANGGDLMTPTFLK TTPEAAKARAAHVLSGQTSEAMRYIMRLNASEGSAKKAAIPYYFVGGKTGTAEKVIGGRYIHNRLFTTFMAAAPMNDPKY LFVTIMDEPQGLPESGGYATAAWNSGVVTGKVIERVAPILGLPPQFEPPVRPFPQMVKLNAYHVNQLGGP >Mature_629_residues SDDADQTLDPAVEPAVSDHEAGLLEAAALAHAAGAPRPLEEEARVPEPRAERAKALLRSMFRLAIERSHMRVAMVGLVFV GVFGTISAKLLMMAIFGEPPSQEHRVAAASSTAFRPDIIDRNGEILATDIRTVSVFAEPGNIYDKDEAVELLTAVLPELN ASELRAKLTQRKDKKGAGFVWVKRELTPKQQAEVHRLGIPGIGFLPDHKRVYPNGVAAAHILGATNLDGVGIAGMEKYID STGLQALNSFGLINKQADLKPVQLSIDLRAQFAVRDELAWGIDHFKAKAGASMILDVKTGEVIALVSMPDFDPNDPKDAL SPDRINRMNVGVYEMGSTFKAMTLAMALDSGKYNVNSTFDTRGGVLNWGRQKIHEYHGTNRVITMPEVFTHSSNIGSAKM ALGVGVPGHKAFLKKMGLLDRLRTELPESAAPIVPSRWTEINTITIAFGHGIAVAPIQAAAAVAAIANGGDLMTPTFLKT TPEAAKARAAHVLSGQTSEAMRYIMRLNASEGSAKKAAIPYYFVGGKTGTAEKVIGGRYIHNRLFTTFMAAAPMNDPKYL FVTIMDEPQGLPESGGYATAAWNSGVVTGKVIERVAPILGLPPQFEPPVRPFPQMVKLNAYHVNQLGGP
Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=518, Percent_Identity=30.1158301158301, Blast_Score=171, Evalue=1e-43, Organism=Escherichia coli, GI1786854, Length=614, Percent_Identity=24.2671009771987, Blast_Score=97, Evalue=5e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: NA
Molecular weight: Translated: 67774; Mature: 67643
Theoretical pI: Translated: 8.61; Mature: 8.61
Prosite motif: PS00146 BETA_LACTAMASE_A
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDDADQTLDPAVEPAVSDHEAGLLEAAALAHAAGAPRPLEEEARVPEPRAERAKALLRS CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHH MFRLAIERSHMRVAMVGLVFVGVFGTISAKLLMMAIFGEPPSQEHRVAAASSTAFRPDII HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC DRNGEILATDIRTVSVFAEPGNIYDKDEAVELLTAVLPELNASELRAKLTQRKDKKGAGF CCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCE VWVKRELTPKQQAEVHRLGIPGIGFLPDHKRVYPNGVAAAHILGATNLDGVGIAGMEKYI EEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCCCHHHHHHH DSTGLQALNSFGLINKQADLKPVQLSIDLRAQFAVRDELAWGIDHFKAKAGASMILDVKT HHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHCCCEEEEEECC GEVIALVSMPDFDPNDPKDALSPDRINRMNVGVYEMGSTFKAMTLAMALDSGKYNVNSTF CCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCEECCCHHHHHHEEHEECCCCEECCCCC DTRGGVLNWGRQKIHEYHGTNRVITMPEVFTHSSNIGSAKMALGVGVPGHKAFLKKMGLL CCCCCCCHHHHHHHHHHCCCCCEEECCHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHH DRLRTELPESAAPIVPSRWTEINTITIAFGHGIAVAPIQAAAAVAAIANGGDLMTPTFLK HHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCEEECHHHHHHHHHHHCCCCCCCCCHHHC TTPEAAKARAAHVLSGQTSEAMRYIMRLNASEGSAKKAAIPYYFVGGKTGTAEKVIGGRY CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHCCHH IHNRLFTTFMAAAPMNDPKYLFVTIMDEPQGLPESGGYATAAWNSGVVTGKVIERVAPIL HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH GLPPQFEPPVRPFPQMVKLNAYHVNQLGGP CCCCCCCCCCCCCCHHEEECEEEECCCCCC >Mature Secondary Structure SDDADQTLDPAVEPAVSDHEAGLLEAAALAHAAGAPRPLEEEARVPEPRAERAKALLRS CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHH MFRLAIERSHMRVAMVGLVFVGVFGTISAKLLMMAIFGEPPSQEHRVAAASSTAFRPDII HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC DRNGEILATDIRTVSVFAEPGNIYDKDEAVELLTAVLPELNASELRAKLTQRKDKKGAGF CCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCE VWVKRELTPKQQAEVHRLGIPGIGFLPDHKRVYPNGVAAAHILGATNLDGVGIAGMEKYI EEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCCCHHHHHHH DSTGLQALNSFGLINKQADLKPVQLSIDLRAQFAVRDELAWGIDHFKAKAGASMILDVKT HHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHCCCEEEEEECC GEVIALVSMPDFDPNDPKDALSPDRINRMNVGVYEMGSTFKAMTLAMALDSGKYNVNSTF CCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCEECCCHHHHHHEEHEECCCCEECCCCC DTRGGVLNWGRQKIHEYHGTNRVITMPEVFTHSSNIGSAKMALGVGVPGHKAFLKKMGLL CCCCCCCHHHHHHHHHHCCCCCEEECCHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHH DRLRTELPESAAPIVPSRWTEINTITIAFGHGIAVAPIQAAAAVAAIANGGDLMTPTFLK HHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCEEECHHHHHHHHHHHCCCCCCCCCHHHC TTPEAAKARAAHVLSGQTSEAMRYIMRLNASEGSAKKAAIPYYFVGGKTGTAEKVIGGRY CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHCCHH IHNRLFTTFMAAAPMNDPKYLFVTIMDEPQGLPESGGYATAAWNSGVVTGKVIERVAPIL HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH GLPPQFEPPVRPFPQMVKLNAYHVNQLGGP CCCCCCCCCCCCCCHHEEECEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3126399 [H]