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The map label for this gene is ftsA [H]

Identifier: 170748769

GI number: 170748769

Start: 2486830

End: 2488152

Strand: Reverse

Name: ftsA [H]

Synonym: Mrad2831_2351

Alternate gene names: 170748769

Gene position: 2488152-2486830 (Counterclockwise)

Preceding gene: 170748770

Following gene: 170748768

Centisome position: 40.94

GC content: 74.15

Gene sequence:

>1323_bases
ATGCACAGCCAACACGGCCTCACGCCGCGCTTGAAGCCGCTCTCCGCCCGGCGCTCGACCACCCTCTCGGTGCTCGACAT
CGGCACGAGCAAGGTGGTCTGCCTCATCGCCGAGCTGCAGCCCGCCGAGGCGCTCACGACGCTCCGCGGCCGCACGCACC
TCGCCCGCATCATCGGCATCGGCCACCAGCGCTCCCTGGGCCTGAAGGGCGGCGCCATCGTCGATCTCGCCGCGGCCGAG
AGCGCGATCCGCCAGGCGGTGCACGCCGCCGAGCGGATGGCCAAGGTCGAGGTCCAGTCGGTCATCGTCAACATGTCGGG
CGGCCGGCTCGCCTCGCAGCATTTTCAGGCGCGGGTGAACGTCCGCTCGGGCACCGTCACGGGCAGCGACGTCGAGCGGG
TGCTCGAGACCGCGAGCGCCCACGGCGTCAGCCCCGGCCGGGCCGTGCTGCACGCCCTGCCCACCGGCTACGCCCTGGAC
GGGCAGGGCGCCGTCATCGACCCGTCGGGCATGATCGGCGAGGCGCTCAGCGTCGACCTGCACGTCGTCACCAGCGAGCT
CGCGGCCGCCCGCAACGTCATGCTGGCGGTGGAGCACTGCCACCTCGGCGTCGAGGCGGTGATCGCCACGCCCTACGCGG
CCGGCCTCTCGGCGCTGGTCGACGACGAGGCCGAGATGGGCGTCTGCGTCGTCGACATGGGCGGCGGCACCACCAGCGTC
GGCGTGTTCTCCGGCGGCCACCTCGTGCACGTGGACGCCCTGGCGGTCGGCGGCCACCACGTCACCATGGACATCGCCCG
CGGCCTCTCCACCCGCATGGCGGCGGCCGAGCGGCTGAAGACCCTCTACGGCTCGGCCCTCTCCACCCCCTCCGACGACC
GCGACATGATCGCCGTGCACGGCGTCGGCGAGGACGAGGGCGAGGCGCCGGCCCACATCCCGCGCTCGCAGCTCGTGCGG
ATCATCAAGCCGCGCGTCGAGGAGGTGGTCGAGCTGGTGCGGGACCGCCTGCGCGACGCGGGCTTCGCCGCGCAGGCCGG
GCGGCGGGTGGTCCTCACCGGCGGCGCCAGCCAGCTCGTCGGCCTGCCCGAGGTCGCCCGCCGCGTCCTCCAGGGTCAGG
TGCGGATCGGACGGCCCCTCGGCATCCGGGGCCTGCCGGAGGCCGCCAAGGGTCCGGCCTTCTCGGCGGCGGTCGGCCTG
CTCGTCTACCCGCAGGTGGCCCATGCCGAGCATTTCGAGCCGCGCGGGCACGGCGCCTTCGCGGCGACCGGGACCGACAA
CTACCTGAACCGGGTCGGCCGCTGGCTCCGGGACAGCTTCTAG

Upstream 100 bases:

>100_bases
GCCCGCGCGGAAGCCCAGAAGGCGAAGAAGAAGGGCGCGGCCAGCTGATGCCCTTCCTGTCGATCTCCGCTCGTCCCGCA
TCCCGCGCCCGGTAGCGTCA

Downstream 100 bases:

>100_bases
GTTTCACGCCCGCCCGCTCGCGCGGGGGGATCGAAGGGAATCCGGCGCCCAGGCGTCGCACGGACAGCACAGTTAGCGAG
AGGCTCGACACCATGGCCAT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MHSQHGLTPRLKPLSARRSTTLSVLDIGTSKVVCLIAELQPAEALTTLRGRTHLARIIGIGHQRSLGLKGGAIVDLAAAE
SAIRQAVHAAERMAKVEVQSVIVNMSGGRLASQHFQARVNVRSGTVTGSDVERVLETASAHGVSPGRAVLHALPTGYALD
GQGAVIDPSGMIGEALSVDLHVVTSELAAARNVMLAVEHCHLGVEAVIATPYAAGLSALVDDEAEMGVCVVDMGGGTTSV
GVFSGGHLVHVDALAVGGHHVTMDIARGLSTRMAAAERLKTLYGSALSTPSDDRDMIAVHGVGEDEGEAPAHIPRSQLVR
IIKPRVEEVVELVRDRLRDAGFAAQAGRRVVLTGGASQLVGLPEVARRVLQGQVRIGRPLGIRGLPEAAKGPAFSAAVGL
LVYPQVAHAEHFEPRGHGAFAATGTDNYLNRVGRWLRDSF

Sequences:

>Translated_440_residues
MHSQHGLTPRLKPLSARRSTTLSVLDIGTSKVVCLIAELQPAEALTTLRGRTHLARIIGIGHQRSLGLKGGAIVDLAAAE
SAIRQAVHAAERMAKVEVQSVIVNMSGGRLASQHFQARVNVRSGTVTGSDVERVLETASAHGVSPGRAVLHALPTGYALD
GQGAVIDPSGMIGEALSVDLHVVTSELAAARNVMLAVEHCHLGVEAVIATPYAAGLSALVDDEAEMGVCVVDMGGGTTSV
GVFSGGHLVHVDALAVGGHHVTMDIARGLSTRMAAAERLKTLYGSALSTPSDDRDMIAVHGVGEDEGEAPAHIPRSQLVR
IIKPRVEEVVELVRDRLRDAGFAAQAGRRVVLTGGASQLVGLPEVARRVLQGQVRIGRPLGIRGLPEAAKGPAFSAAVGL
LVYPQVAHAEHFEPRGHGAFAATGTDNYLNRVGRWLRDSF
>Mature_440_residues
MHSQHGLTPRLKPLSARRSTTLSVLDIGTSKVVCLIAELQPAEALTTLRGRTHLARIIGIGHQRSLGLKGGAIVDLAAAE
SAIRQAVHAAERMAKVEVQSVIVNMSGGRLASQHFQARVNVRSGTVTGSDVERVLETASAHGVSPGRAVLHALPTGYALD
GQGAVIDPSGMIGEALSVDLHVVTSELAAARNVMLAVEHCHLGVEAVIATPYAAGLSALVDDEAEMGVCVVDMGGGTTSV
GVFSGGHLVHVDALAVGGHHVTMDIARGLSTRMAAAERLKTLYGSALSTPSDDRDMIAVHGVGEDEGEAPAHIPRSQLVR
IIKPRVEEVVELVRDRLRDAGFAAQAGRRVVLTGGASQLVGLPEVARRVLQGQVRIGRPLGIRGLPEAAKGPAFSAAVGL
LVYPQVAHAEHFEPRGHGAFAATGTDNYLNRVGRWLRDSF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=423, Percent_Identity=35.2245862884161, Blast_Score=239, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46016; Mature: 46016

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSQHGLTPRLKPLSARRSTTLSVLDIGTSKVVCLIAELQPAEALTTLRGRTHLARIIGI
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC
GHQRSLGLKGGAIVDLAAAESAIRQAVHAAERMAKVEVQSVIVNMSGGRLASQHFQARVN
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEHHEEECCCCCHHHHHHEEEEE
VRSGTVTGSDVERVLETASAHGVSPGRAVLHALPTGYALDGQGAVIDPSGMIGEALSVDL
EECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCEECCCCCCCHHHEEEH
HVVTSELAAARNVMLAVEHCHLGVEAVIATPYAAGLSALVDDEAEMGVCVVDMGGGTTSV
HHHHHHHHHHHHHHEEEHHHHCCHHHEEECCHHHHHHHHHCCCCCCCEEEEEECCCCEEE
GVFSGGHLVHVDALAVGGHHVTMDIARGLSTRMAAAERLKTLYGSALSTPSDDRDMIAVH
EEECCCCEEEEEEEEECCEEEEHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GVGEDEGEAPAHIPRSQLVRIIKPRVEEVVELVRDRLRDAGFAAQAGRRVVLTGGASQLV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHC
GLPEVARRVLQGQVRIGRPLGIRGLPEAAKGPAFSAAVGLLVYPQVAHAEHFEPRGHGAF
CCHHHHHHHHHCCCEECCCCCCCCCCCHHCCCCHHHHHHHHCCCCHHHHCCCCCCCCCEE
AATGTDNYLNRVGRWLRDSF
EECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSQHGLTPRLKPLSARRSTTLSVLDIGTSKVVCLIAELQPAEALTTLRGRTHLARIIGI
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC
GHQRSLGLKGGAIVDLAAAESAIRQAVHAAERMAKVEVQSVIVNMSGGRLASQHFQARVN
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEHHEEECCCCCHHHHHHEEEEE
VRSGTVTGSDVERVLETASAHGVSPGRAVLHALPTGYALDGQGAVIDPSGMIGEALSVDL
EECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCEECCCCCCCHHHEEEH
HVVTSELAAARNVMLAVEHCHLGVEAVIATPYAAGLSALVDDEAEMGVCVVDMGGGTTSV
HHHHHHHHHHHHHHEEEHHHHCCHHHEEECCHHHHHHHHHCCCCCCCEEEEEECCCCEEE
GVFSGGHLVHVDALAVGGHHVTMDIARGLSTRMAAAERLKTLYGSALSTPSDDRDMIAVH
EEECCCCEEEEEEEEECCEEEEHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GVGEDEGEAPAHIPRSQLVRIIKPRVEEVVELVRDRLRDAGFAAQAGRRVVLTGGASQLV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHC
GLPEVARRVLQGQVRIGRPLGIRGLPEAAKGPAFSAAVGLLVYPQVAHAEHFEPRGHGAF
CCHHHHHHHHHCCCEECCCCCCCCCCCHHCCCCHHHHHHHHCCCCHHHHCCCCCCCCCEE
AATGTDNYLNRVGRWLRDSF
EECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]