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The map label for this gene is dapA [H]

Identifier: 170748387

GI number: 170748387

Start: 2097367

End: 2098320

Strand: Reverse

Name: dapA [H]

Synonym: Mrad2831_1969

Alternate gene names: 170748387

Gene position: 2098320-2097367 (Counterclockwise)

Preceding gene: 170748388

Following gene: 170748386

Centisome position: 34.52

GC content: 72.12

Gene sequence:

>954_bases
ATGGCCTTCGATCGACACATCTTCTCCGGCACGATCCCGGCCCTGATGACGCCCTGCCGGCCGGACCGGTCGCCCGACCT
CGACGCCCTCGCGCGCAAGGGGCGGGAACTCGTCGATGCCGGCATGTCGGCGGTCGTCTACTGCGGCTCGATGGGCGACT
GGCCGCTGCTCACCGACGAGGAGCGGATGGCGGGCGTCGAGCGGCTGCTCGCCGCCGGCGTCCCGGTGATCGTCGGGACC
GGCGCGCAGAACCCGAAGCGGGCCGCGGCGCTCGCGGCGCACGCCAAGGCGGCCGGCGCCCACGGCCTGATGATCATCCC
GCGGGTCCTATCGCGCGGCAGCTCGGCCGCGGCCCAGGAGGCGCATTTCGGCGGCATCCTGGAGGCCGCCGTCGACCTGC
CGTCGGTGATCTACAACAGCCCCTACTACGGGTTCGAGACCCGGGCGGACCTGTTCTTCCGCCTGCGCGCCCGCCACCCG
CACCTCGTCGGCTTCAAGGAGTTCGGCGGCGCGGCCTCGCTCACCTACGCGGCCGAGCACATCACCGGCCAGTCGCCCGA
CATCACCCTGATGGTCGGCGTGGATACCCAGGTGGTGCACGGCTACGTCCATTGCGGCGCCCGGGGCGCCATCACGGGCA
TCGGCAACGTCCTGCCGCGGGAGGTGCTCCACCTCGTCGCCCTGTGCGAGAAGGCCGCCGCGGGCGACGTCCCGGCCCGG
CGCCGGGCCGAGGAACTCGACGCCGCCCTGGCGATCCTGTCGAGCTTCGACGAGGGGACGGATCTCGTCCTCTACTACAA
GCACCTGATGGTGCTGGAGGGGAACCCGGAATACGCGCTCCACTTCAACGCCACCGACGCGCTGAGCGCCGGTCAGCGCC
ACTACGCGGAGACGCAGCTGCGCCTGTTCAAGGCGTGGTACGCGCGCTGGTCGGAGGAGGCCGCCGGGGCCTGA

Upstream 100 bases:

>100_bases
CTTGCCAGACTCGCGCGGCGCTGCCATGGAGGGGCGTGCCGCCCCGCGAGGCCCGCAAGGCCGGCCGGGACGATCCCACC
TCCCAGCAGGCGAGCCGGCG

Downstream 100 bases:

>100_bases
TCCCCGGCCGCGGCCGAACGCAGGGCAGCCCGTCTTTGCGCGGGACCGCCCGTCGGCGCTATGGCGGGTGCGAGATCGGC
CACATCCGCGAACCCTCCCA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAFDRHIFSGTIPALMTPCRPDRSPDLDALARKGRELVDAGMSAVVYCGSMGDWPLLTDEERMAGVERLLAAGVPVIVGT
GAQNPKRAAALAAHAKAAGAHGLMIIPRVLSRGSSAAAQEAHFGGILEAAVDLPSVIYNSPYYGFETRADLFFRLRARHP
HLVGFKEFGGAASLTYAAEHITGQSPDITLMVGVDTQVVHGYVHCGARGAITGIGNVLPREVLHLVALCEKAAAGDVPAR
RRAEELDAALAILSSFDEGTDLVLYYKHLMVLEGNPEYALHFNATDALSAGQRHYAETQLRLFKAWYARWSEEAAGA

Sequences:

>Translated_317_residues
MAFDRHIFSGTIPALMTPCRPDRSPDLDALARKGRELVDAGMSAVVYCGSMGDWPLLTDEERMAGVERLLAAGVPVIVGT
GAQNPKRAAALAAHAKAAGAHGLMIIPRVLSRGSSAAAQEAHFGGILEAAVDLPSVIYNSPYYGFETRADLFFRLRARHP
HLVGFKEFGGAASLTYAAEHITGQSPDITLMVGVDTQVVHGYVHCGARGAITGIGNVLPREVLHLVALCEKAAAGDVPAR
RRAEELDAALAILSSFDEGTDLVLYYKHLMVLEGNPEYALHFNATDALSAGQRHYAETQLRLFKAWYARWSEEAAGA
>Mature_316_residues
AFDRHIFSGTIPALMTPCRPDRSPDLDALARKGRELVDAGMSAVVYCGSMGDWPLLTDEERMAGVERLLAAGVPVIVGTG
AQNPKRAAALAAHAKAAGAHGLMIIPRVLSRGSSAAAQEAHFGGILEAAVDLPSVIYNSPYYGFETRADLFFRLRARHPH
LVGFKEFGGAASLTYAAEHITGQSPDITLMVGVDTQVVHGYVHCGARGAITGIGNVLPREVLHLVALCEKAAAGDVPARR
RAEELDAALAILSSFDEGTDLVLYYKHLMVLEGNPEYALHFNATDALSAGQRHYAETQLRLFKAWYARWSEEAAGA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1786463, Length=276, Percent_Identity=27.8985507246377, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082415, Length=222, Percent_Identity=26.1261261261261, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788823, Length=233, Percent_Identity=29.1845493562232, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33961; Mature: 33830

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDRHIFSGTIPALMTPCRPDRSPDLDALARKGRELVDAGMSAVVYCGSMGDWPLLTDE
CCCCCCHHCCCHHHHHCCCCCCCCCCHHHHHHCCHHHHHCCCCEEEEECCCCCCCCCCCH
ERMAGVERLLAAGVPVIVGTGAQNPKRAAALAAHAKAAGAHGLMIIPRVLSRGSSAAAQE
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHH
AHFGGILEAAVDLPSVIYNSPYYGFETRADLFFRLRARHPHLVGFKEFGGAASLTYAAEH
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEECHHHHCCCHHHHHHHHH
ITGQSPDITLMVGVDTQVVHGYVHCGARGAITGIGNVLPREVLHLVALCEKAAAGDVPAR
HCCCCCCEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RRAEELDAALAILSSFDEGTDLVLYYKHLMVLEGNPEYALHFNATDALSAGQRHYAETQL
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
RLFKAWYARWSEEAAGA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFDRHIFSGTIPALMTPCRPDRSPDLDALARKGRELVDAGMSAVVYCGSMGDWPLLTDE
CCCCCHHCCCHHHHHCCCCCCCCCCHHHHHHCCHHHHHCCCCEEEEECCCCCCCCCCCH
ERMAGVERLLAAGVPVIVGTGAQNPKRAAALAAHAKAAGAHGLMIIPRVLSRGSSAAAQE
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHH
AHFGGILEAAVDLPSVIYNSPYYGFETRADLFFRLRARHPHLVGFKEFGGAASLTYAAEH
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEECHHHHCCCHHHHHHHHH
ITGQSPDITLMVGVDTQVVHGYVHCGARGAITGIGNVLPREVLHLVALCEKAAAGDVPAR
HCCCCCCEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RRAEELDAALAILSSFDEGTDLVLYYKHLMVLEGNPEYALHFNATDALSAGQRHYAETQL
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
RLFKAWYARWSEEAAGA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]