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The map label for this gene is ycgM [C]

Identifier: 170748207

GI number: 170748207

Start: 1908118

End: 1909146

Strand: Reverse

Name: ycgM [C]

Synonym: Mrad2831_1789

Alternate gene names: 170748207

Gene position: 1909146-1908118 (Counterclockwise)

Preceding gene: 170748208

Following gene: 170748203

Centisome position: 31.41

GC content: 69.97

Gene sequence:

>1029_bases
ATGGGCAACCGACGCGAATTCCTGACCGCCACGGCCGCCGGCCTGGCCGCCGCCGCGGCGCCGGCCCGCGCCGCCGAGGA
GCAGACGGCGGCGCCGAGATCCACGCCGGCGGGGGCACCCCCCTTCGGCATGCCCCGCGACATGGTCCTCCTCAACATGC
GCCGCGGCGACGGCTACGCCCTGGGCGTGAAGACGAGGGACGGCGTCCTCGACGTCGCCGCCGCCGGCCGGGCGCTCGGG
ATGCCGGTCCCCGCCGACATGGACGACCTCCTCCAGAACGGGCGCGGCCCGGCGCTGCGGGCGCTGATCGACGCGGTCGA
GGCCGCCCCCGACGGGCGCTTCGTGCTGGCGGAATCCGGCATCGCCTACGCGCCGGTGGTCACGCGGCCCGAGAAGATCA
TCATGATGGGCTTCAACTACCGCCACCACGCGGAGGAGACCGGCACGCCGATCCCCAAGGACCCGCCGCTGTTCAACAAG
TACAACAACGCCCTGAACCACCACGGGGGCACGATCGCGCTGCCGACCCAGGCGGCGCGGGAATTCGACTACGAGACCGA
GCTGGTGATGGTGTTCGGCCGGGAATGCCGGAACGTGTCCGAGGCGGACGCCCTCGATTATCTCGCCGGCTACTGCACGG
GCAACGATTTCAGCGCCCGGGACCTCCAGACGCTGACCTCCCAGTTCATGATCGGCAAGACCTCGGACGGGTTCGCCCCG
CTCGGCCCCTACCTGGTGACCGCCGACCGGGTGAAGGACCCGAACGATCTCAAGCTGAAGACGCTGGTCAACGGCCAGGT
GCGCCAGGACTGGAGCACCAACGACATGATCTTCAACTGCCGCCAGCTCATCAGCTTCGCGTCGAAGGTGATGACGATCC
GGCCGGGCGACATCTTCTACACGGGCACGCCGCAGGGCGTGATCTTCGGCGAGAAGATCCCGCGCAAGGACCGGGCCTGG
CTGAAGCCCGGCGACGAGGTGGTCTCGGAGCTGGAAGGGCTCGGCGCGCTGCGCTTCAGGCTGGTCTGA

Upstream 100 bases:

>100_bases
CCCGGACCCCGCCGCGGGTCCTGGCGGCGCCGCCGCCGGCCGTGCAGGCTCCGCCCGGTTCACGCCCGCGACCAGACGGG
CCGACCGGAGGAGAGGCAGC

Downstream 100 bases:

>100_bases
TCCGTCGTCCGATCGGTGCGACCCGCACCGTCATCACCGACGCGACGCGCGGCCGGCCCCCTCTCCCGTGCGGGAGACGG
GGGCCCGCGCGCGAGCCGCG

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MGNRREFLTATAAGLAAAAAPARAAEEQTAAPRSTPAGAPPFGMPRDMVLLNMRRGDGYALGVKTRDGVLDVAAAGRALG
MPVPADMDDLLQNGRGPALRALIDAVEAAPDGRFVLAESGIAYAPVVTRPEKIIMMGFNYRHHAEETGTPIPKDPPLFNK
YNNALNHHGGTIALPTQAAREFDYETELVMVFGRECRNVSEADALDYLAGYCTGNDFSARDLQTLTSQFMIGKTSDGFAP
LGPYLVTADRVKDPNDLKLKTLVNGQVRQDWSTNDMIFNCRQLISFASKVMTIRPGDIFYTGTPQGVIFGEKIPRKDRAW
LKPGDEVVSELEGLGALRFRLV

Sequences:

>Translated_342_residues
MGNRREFLTATAAGLAAAAAPARAAEEQTAAPRSTPAGAPPFGMPRDMVLLNMRRGDGYALGVKTRDGVLDVAAAGRALG
MPVPADMDDLLQNGRGPALRALIDAVEAAPDGRFVLAESGIAYAPVVTRPEKIIMMGFNYRHHAEETGTPIPKDPPLFNK
YNNALNHHGGTIALPTQAAREFDYETELVMVFGRECRNVSEADALDYLAGYCTGNDFSARDLQTLTSQFMIGKTSDGFAP
LGPYLVTADRVKDPNDLKLKTLVNGQVRQDWSTNDMIFNCRQLISFASKVMTIRPGDIFYTGTPQGVIFGEKIPRKDRAW
LKPGDEVVSELEGLGALRFRLV
>Mature_341_residues
GNRREFLTATAAGLAAAAAPARAAEEQTAAPRSTPAGAPPFGMPRDMVLLNMRRGDGYALGVKTRDGVLDVAAAGRALGM
PVPADMDDLLQNGRGPALRALIDAVEAAPDGRFVLAESGIAYAPVVTRPEKIIMMGFNYRHHAEETGTPIPKDPPLFNKY
NNALNHHGGTIALPTQAAREFDYETELVMVFGRECRNVSEADALDYLAGYCTGNDFSARDLQTLTSQFMIGKTSDGFAPL
GPYLVTADRVKDPNDLKLKTLVNGQVRQDWSTNDMIFNCRQLISFASKVMTIRPGDIFYTGTPQGVIFGEKIPRKDRAWL
KPGDEVVSELEGLGALRFRLV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=312, Percent_Identity=37.5, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI40786394, Length=312, Percent_Identity=37.1794871794872, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI13654274, Length=215, Percent_Identity=33.4883720930233, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI215422413, Length=181, Percent_Identity=36.4640883977901, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI66348062, Length=181, Percent_Identity=36.4640883977901, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1787428, Length=206, Percent_Identity=31.0679611650485, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17557057, Length=180, Percent_Identity=35, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324161, Length=236, Percent_Identity=28.8135593220339, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28572127, Length=293, Percent_Identity=37.542662116041, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24663695, Length=286, Percent_Identity=31.1188811188811, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571789, Length=180, Percent_Identity=35, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 37074; Mature: 36943

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRREFLTATAAGLAAAAAPARAAEEQTAAPRSTPAGAPPFGMPRDMVLLNMRRGDGYA
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCEE
LGVKTRDGVLDVAAAGRALGMPVPADMDDLLQNGRGPALRALIDAVEAAPDGRFVLAESG
EEEECCCCEEEHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCC
IAYAPVVTRPEKIIMMGFNYRHHAEETGTPIPKDPPLFNKYNNALNHHGGTIALPTQAAR
CEECCEECCCCEEEEECCCCHHCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECHHHHH
EFDYETELVMVFGRECRNVSEADALDYLAGYCTGNDFSARDLQTLTSQFMIGKTSDGFAP
HCCCCCEEEEEECHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCCCCC
LGPYLVTADRVKDPNDLKLKTLVNGQVRQDWSTNDMIFNCRQLISFASKVMTIRPGDIFY
CCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEE
TGTPQGVIFGEKIPRKDRAWLKPGDEVVSELEGLGALRFRLV
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
GNRREFLTATAAGLAAAAAPARAAEEQTAAPRSTPAGAPPFGMPRDMVLLNMRRGDGYA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCEE
LGVKTRDGVLDVAAAGRALGMPVPADMDDLLQNGRGPALRALIDAVEAAPDGRFVLAESG
EEEECCCCEEEHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCC
IAYAPVVTRPEKIIMMGFNYRHHAEETGTPIPKDPPLFNKYNNALNHHGGTIALPTQAAR
CEECCEECCCCEEEEECCCCHHCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECHHHHH
EFDYETELVMVFGRECRNVSEADALDYLAGYCTGNDFSARDLQTLTSQFMIGKTSDGFAP
HCCCCCEEEEEECHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCCCCC
LGPYLVTADRVKDPNDLKLKTLVNGQVRQDWSTNDMIFNCRQLISFASKVMTIRPGDIFY
CCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEE
TGTPQGVIFGEKIPRKDRAWLKPGDEVVSELEGLGALRFRLV
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]