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The map label for this gene is fhuA [H]

Identifier: 170748198

GI number: 170748198

Start: 1896341

End: 1898521

Strand: Reverse

Name: fhuA [H]

Synonym: Mrad2831_1780

Alternate gene names: 170748198

Gene position: 1898521-1896341 (Counterclockwise)

Preceding gene: 170748199

Following gene: 170748191

Centisome position: 31.24

GC content: 68.87

Gene sequence:

>2181_bases
ATGTCTGCCGCCCGGATCGACGTCGTCGATCGCATCAAATACTGCCGGTCGCGCCTGAATTTCTGCAGCACTGGGCTCGC
GACGTCGCTCCTTCTGCTCGCGCCGACAGAGATCCGCGCGCAATCCGAGCCGGTCGCCGACGAGGTCGTTCTCTCCGAAC
TCAGTGTTGCGGGCACGGGCCCCGTCAGCGAGCGGGCCGACGGTCCCGTCGTCGGCTACCGGGCGACGCGCTCCGCGACC
GCCACGCGCACCGACACGCCGGTGCGCGACTCGCCGCAATCGATCAACGTCGTGCCCCGTTCGGTGATCACCGACCAGCA
GGACCTGCGGCTGACCGATGCCGTGACCAACGTCAGCAACGTGGTTCTCGGCAGCACGGTGCAGGGACGGTCGCAGAACT
ACCTGATCCGCGGCTTCTCCACGCAGGTCTTCGCCGTCGACGGCGTGCTGGTCGATCCGGCCATCAACTTCTACCCGGTG
ACGCGCGACCTCGTGGATGCGGAGCGCGTCGAGGTGATCAAGGGACCGGCCTCGGTGCTGTTCGGGCGGGGAGATCCCGG
CGGCGTCATCAACATCGTGACCCGCCGGCCGACATTCGAGCCCACGGCCGACGCGAGTGTTCAGGGTGGCAGCTTCGGCT
TCCGGCGCTTCCAGGGCTCCGTGTCGAGCGCGCTGCCCGCCGTCGAAGGACTCGCCGCGCGCCTGAGCTTCGCCGCCCAG
GAGGATCCGACCTTCCGCAATTACGGCGGCGACACCAACCGGCGCGTCTTCGTGGCGCCGGCCTTCAGCTGGACGCCGAG
CGCCGACACCCGGGTCTACGTGAACTCGGAATTCACCAACCAGCACACCCAGTACGACGAGGGGCTGGTGGCCTTCCGCG
GCCGCGTCCCGCTCGACAACATCGGCCGGTTCTACGGTGAGCCGTCCTCGCGCTACTTCGGCGCCTTCAACACGATCACC
ATGCGGGCCGAGCACGACGTCAACGAGAACCTGACGCTCCGGCAGGTCATCGCCGGGCAATGGGGCACGTTCGACGTGTT
CGCGGCCCGTGCCCTATCGGTCAACAATGCCGGCACGCTGCTGAGCCGGCGCGAAGCCACGGTCAACTCGCGCTTCGCCG
CGGTCGACAGCCAGACCGAGGCCGTGATGAAGTTCGACACCTTCGGCTTCGCCCATACGGCGCTCCTCGGGCTCGAGTAC
TCGAACGGCTTCCGCCACGCCTTCTCCCAGCAGGGCAACCTCGCCCCGGTCAGCTTCCTCAACCCGATGTTCGGCGCGGC
CTTCCAGCCGCTCCAGTTCCAGGCCGACCTGAAGCAGAAGCTGGAGGTGTTCGGGCTCTACGCCCAGGACCAGATCGTGC
TCGCGCCGGGCTTGCAGCTCGTCGTCGGGGCCCGGTTCGATCTCGGCAGCCAGTACTATTTCAACCGCCAGCCGGCCTCG
CGGACCCAGCCGCCCGAGCAGACCCTGTTCGGCGCCTCGCCGCGGGTCGGACTGATCTACCGGCCGTTCGAGCCGCTGAC
CTTCTACGCGAGCTACGCCACGTCGTTCCTGCCGCAGACCGCCAGCGTGCTGAACGTGGCGAGCCCCCCGCCCAGCACGG
GCGAGCAGGTCGAGGCCGGCACCCGGGTCGATCTCACGCCCGGCCTGACCCTGAGCGCGGCCGCCTTCCAGATCGTCCGG
GACAACGTCGCGGCCACCGACCCGCGCAATCCCACCTTCTCGGTCATCACCGGCCAGCAGCGGTCGCGGGGTGTCGAGGC
CGATCTCGCCGGTGAGATCCTGCCCGGGTGGAGCATCATCGGCAGCGTCGGCCTGATCGACGCGCGGATCACCAAGGACA
CGACCTTCGCGGTCGGCAACCGGCTCGCCGGCGTGCCGGTGTTCAGCGGCAGCCTGTGGACGACCTACGCGTTCCAGGAC
GGCCCGCTGCGCGGGCTCGGGCTCGGGCTCGGCGTCACCCATGTCGGCCGACGCTACGGCGACCTCGACAACAGCTTCAC
CGTGGGCGCCTACAACCGGCTCGACGCGCTCGTGTACTACGATTTCGACGCCCACTGGCGCCTGTCGGTGAACATGCGCA
ACCTGACGAACGCGCGCTACATCGAGGCGCCGACCAACGCGACCAACAACACCCCCGGGGCGCCGTTCACGGTGCTGGCG
ACGATCACCGCCCGGCTCTGA

Upstream 100 bases:

>100_bases
CACCCGCGGCTTTCCCGATCGGCGTTGAGAAAAGACGGCGTATGCAATCTAGAAATACCGCATCGCGTCGATACGTCGCT
CTTGAGAACGATTTTAAAGC

Downstream 100 bases:

>100_bases
CGGGCCGAAACCTGCGCGGGGCGGGCCCCATCGAACGATGGCCCACCGGAGGCTGCCGTCAGGGGCTCGCCGTTCGGACG
GCGCCCGCCGGCGCCCCGGC

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSAARIDVVDRIKYCRSRLNFCSTGLATSLLLLAPTEIRAQSEPVADEVVLSELSVAGTGPVSERADGPVVGYRATRSAT
ATRTDTPVRDSPQSINVVPRSVITDQQDLRLTDAVTNVSNVVLGSTVQGRSQNYLIRGFSTQVFAVDGVLVDPAINFYPV
TRDLVDAERVEVIKGPASVLFGRGDPGGVINIVTRRPTFEPTADASVQGGSFGFRRFQGSVSSALPAVEGLAARLSFAAQ
EDPTFRNYGGDTNRRVFVAPAFSWTPSADTRVYVNSEFTNQHTQYDEGLVAFRGRVPLDNIGRFYGEPSSRYFGAFNTIT
MRAEHDVNENLTLRQVIAGQWGTFDVFAARALSVNNAGTLLSRREATVNSRFAAVDSQTEAVMKFDTFGFAHTALLGLEY
SNGFRHAFSQQGNLAPVSFLNPMFGAAFQPLQFQADLKQKLEVFGLYAQDQIVLAPGLQLVVGARFDLGSQYYFNRQPAS
RTQPPEQTLFGASPRVGLIYRPFEPLTFYASYATSFLPQTASVLNVASPPPSTGEQVEAGTRVDLTPGLTLSAAAFQIVR
DNVAATDPRNPTFSVITGQQRSRGVEADLAGEILPGWSIIGSVGLIDARITKDTTFAVGNRLAGVPVFSGSLWTTYAFQD
GPLRGLGLGLGVTHVGRRYGDLDNSFTVGAYNRLDALVYYDFDAHWRLSVNMRNLTNARYIEAPTNATNNTPGAPFTVLA
TITARL

Sequences:

>Translated_726_residues
MSAARIDVVDRIKYCRSRLNFCSTGLATSLLLLAPTEIRAQSEPVADEVVLSELSVAGTGPVSERADGPVVGYRATRSAT
ATRTDTPVRDSPQSINVVPRSVITDQQDLRLTDAVTNVSNVVLGSTVQGRSQNYLIRGFSTQVFAVDGVLVDPAINFYPV
TRDLVDAERVEVIKGPASVLFGRGDPGGVINIVTRRPTFEPTADASVQGGSFGFRRFQGSVSSALPAVEGLAARLSFAAQ
EDPTFRNYGGDTNRRVFVAPAFSWTPSADTRVYVNSEFTNQHTQYDEGLVAFRGRVPLDNIGRFYGEPSSRYFGAFNTIT
MRAEHDVNENLTLRQVIAGQWGTFDVFAARALSVNNAGTLLSRREATVNSRFAAVDSQTEAVMKFDTFGFAHTALLGLEY
SNGFRHAFSQQGNLAPVSFLNPMFGAAFQPLQFQADLKQKLEVFGLYAQDQIVLAPGLQLVVGARFDLGSQYYFNRQPAS
RTQPPEQTLFGASPRVGLIYRPFEPLTFYASYATSFLPQTASVLNVASPPPSTGEQVEAGTRVDLTPGLTLSAAAFQIVR
DNVAATDPRNPTFSVITGQQRSRGVEADLAGEILPGWSIIGSVGLIDARITKDTTFAVGNRLAGVPVFSGSLWTTYAFQD
GPLRGLGLGLGVTHVGRRYGDLDNSFTVGAYNRLDALVYYDFDAHWRLSVNMRNLTNARYIEAPTNATNNTPGAPFTVLA
TITARL
>Mature_725_residues
SAARIDVVDRIKYCRSRLNFCSTGLATSLLLLAPTEIRAQSEPVADEVVLSELSVAGTGPVSERADGPVVGYRATRSATA
TRTDTPVRDSPQSINVVPRSVITDQQDLRLTDAVTNVSNVVLGSTVQGRSQNYLIRGFSTQVFAVDGVLVDPAINFYPVT
RDLVDAERVEVIKGPASVLFGRGDPGGVINIVTRRPTFEPTADASVQGGSFGFRRFQGSVSSALPAVEGLAARLSFAAQE
DPTFRNYGGDTNRRVFVAPAFSWTPSADTRVYVNSEFTNQHTQYDEGLVAFRGRVPLDNIGRFYGEPSSRYFGAFNTITM
RAEHDVNENLTLRQVIAGQWGTFDVFAARALSVNNAGTLLSRREATVNSRFAAVDSQTEAVMKFDTFGFAHTALLGLEYS
NGFRHAFSQQGNLAPVSFLNPMFGAAFQPLQFQADLKQKLEVFGLYAQDQIVLAPGLQLVVGARFDLGSQYYFNRQPASR
TQPPEQTLFGASPRVGLIYRPFEPLTFYASYATSFLPQTASVLNVASPPPSTGEQVEAGTRVDLTPGLTLSAAAFQIVRD
NVAATDPRNPTFSVITGQQRSRGVEADLAGEILPGWSIIGSVGLIDARITKDTTFAVGNRLAGVPVFSGSLWTTYAFQDG
PLRGLGLGLGVTHVGRRYGDLDNSFTVGAYNRLDALVYYDFDAHWRLSVNMRNLTNARYIEAPTNATNNTPGAPFTVLAT
ITARL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=736, Percent_Identity=29.6195652173913, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787024, Length=719, Percent_Identity=25.7301808066759, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1787344, Length=728, Percent_Identity=24.8626373626374, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78627; Mature: 78496

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAARIDVVDRIKYCRSRLNFCSTGLATSLLLLAPTEIRAQSEPVADEVVLSELSVAGTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCCCHHHHHHHHHCCCCCC
PVSERADGPVVGYRATRSATATRTDTPVRDSPQSINVVPRSVITDQQDLRLTDAVTNVSN
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHCCCHHCCHHHHHHHHHH
VVLGSTVQGRSQNYLIRGFSTQVFAVDGVLVDPAINFYPVTRDLVDAERVEVIKGPASVL
EEECCCCCCCCCCEEEEECCEEEEEECCEEECCCCCEEECCHHHHCHHHHHEEECCCCEE
FGRGDPGGVINIVTRRPTFEPTADASVQGGSFGFRRFQGSVSSALPAVEGLAARLSFAAQ
EECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCC
EDPTFRNYGGDTNRRVFVAPAFSWTPSADTRVYVNSEFTNQHTQYDEGLVAFRGRVPLDN
CCCCHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHH
IGRFYGEPSSRYFGAFNTITMRAEHDVNENLTLRQVIAGQWGTFDVFAARALSVNNAGTL
HHHHHCCCCCCEEECEEEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHEEECCCCCCH
LSRREATVNSRFAAVDSQTEAVMKFDTFGFAHTALLGLEYSNGFRHAFSQQGNLAPVSFL
HHHHHHHHCCEEEECCCCCHHEEEEECCCHHEEEEEEEECCCCHHHHHHCCCCCCCHHHH
NPMFGAAFQPLQFQADLKQKLEVFGLYAQDQIVLAPGLQLVVGARFDLGSQYYFNRQPAS
CHHHHHCCCCCEEHHHHHHHHHHEEEEECCCEEECCCCEEEEEECCCCCCCEEECCCCCC
RTQPPEQTLFGASPRVGLIYRPFEPLTFYASYATSFLPQTASVLNVASPPPSTGEQVEAG
CCCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHEECCCCCCCCCCCCCCC
TRVDLTPGLTLSAAAFQIVRDNVAATDPRNPTFSVITGQQRSRGVEADLAGEILPGWSII
CEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCHHHH
GSVGLIDARITKDTTFAVGNRLAGVPVFSGSLWTTYAFQDGPLRGLGLGLGVTHVGRRYG
CCCCEEEEEECCCCEEECCCCCCCCEEECCCEEEEEEECCCCCCEEEECCCHHHHHHHHC
DLDNSFTVGAYNRLDALVYYDFDAHWRLSVNMRNLTNARYIEAPTNATNNTPGAPFTVLA
CCCCCEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCEEEEE
TITARL
EEECCC
>Mature Secondary Structure 
SAARIDVVDRIKYCRSRLNFCSTGLATSLLLLAPTEIRAQSEPVADEVVLSELSVAGTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCCCHHHHHHHHHCCCCCC
PVSERADGPVVGYRATRSATATRTDTPVRDSPQSINVVPRSVITDQQDLRLTDAVTNVSN
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHCCCHHCCHHHHHHHHHH
VVLGSTVQGRSQNYLIRGFSTQVFAVDGVLVDPAINFYPVTRDLVDAERVEVIKGPASVL
EEECCCCCCCCCCEEEEECCEEEEEECCEEECCCCCEEECCHHHHCHHHHHEEECCCCEE
FGRGDPGGVINIVTRRPTFEPTADASVQGGSFGFRRFQGSVSSALPAVEGLAARLSFAAQ
EECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCC
EDPTFRNYGGDTNRRVFVAPAFSWTPSADTRVYVNSEFTNQHTQYDEGLVAFRGRVPLDN
CCCCHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHH
IGRFYGEPSSRYFGAFNTITMRAEHDVNENLTLRQVIAGQWGTFDVFAARALSVNNAGTL
HHHHHCCCCCCEEECEEEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHEEECCCCCCH
LSRREATVNSRFAAVDSQTEAVMKFDTFGFAHTALLGLEYSNGFRHAFSQQGNLAPVSFL
HHHHHHHHCCEEEECCCCCHHEEEEECCCHHEEEEEEEECCCCHHHHHHCCCCCCCHHHH
NPMFGAAFQPLQFQADLKQKLEVFGLYAQDQIVLAPGLQLVVGARFDLGSQYYFNRQPAS
CHHHHHCCCCCEEHHHHHHHHHHEEEEECCCEEECCCCEEEEEECCCCCCCEEECCCCCC
RTQPPEQTLFGASPRVGLIYRPFEPLTFYASYATSFLPQTASVLNVASPPPSTGEQVEAG
CCCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHEECCCCCCCCCCCCCCC
TRVDLTPGLTLSAAAFQIVRDNVAATDPRNPTFSVITGQQRSRGVEADLAGEILPGWSII
CEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCCCCHHHH
GSVGLIDARITKDTTFAVGNRLAGVPVFSGSLWTTYAFQDGPLRGLGLGLGVTHVGRRYG
CCCCEEEEEECCCCEEECCCCCCCCEEECCCEEEEEEECCCCCCEEEECCCHHHHHHHHC
DLDNSFTVGAYNRLDALVYYDFDAHWRLSVNMRNLTNARYIEAPTNATNNTPGAPFTVLA
CCCCCEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCEEEEE
TITARL
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]