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The map label for this gene is mcp4 [H]

Identifier: 170748184

GI number: 170748184

Start: 1875786

End: 1877513

Strand: Reverse

Name: mcp4 [H]

Synonym: Mrad2831_1766

Alternate gene names: 170748184

Gene position: 1877513-1875786 (Counterclockwise)

Preceding gene: 170748185

Following gene: 170748183

Centisome position: 30.89

GC content: 75.52

Gene sequence:

>1728_bases
ATGCACCCCGCGTCGGACGCGGCGGCCCTGCGCCGCGACGCCCGGATTCCCATGACCCTGCGCATCGGCACCCGTCTCCA
GTTGATCACCGCGATGGCCCTGCTCGGCATGGCGGTGCTGATCGGGCTGGCGGCCTGGGACCTGTCCCGGGTAATCGGCG
ACGCGCGCGCGCTGCAGACCCGCAACCTCGTCGAGGCGGCGCACGGGGCGCTGGCCTACTTCGAGGGCGAGGAGCGGGCG
GGGCGGATGAGCCGCGCGGCCGCCCAGGCCGCCGCGATCGCGGAGATCCGCGGCCTGCACTACGCCGGCAGCGAGTATTT
CTGGATCCAGGACATGCAGCCGCGGATGCTGCTGCATCCGAAGGACGCGCTGATCGGTCAGGATGTCGGCGGCCTCACCG
ATCCGGCCGGCAAGCACCTCTTCGTCGCGATGGTGGAGCAGGTTCGCCGGGCGGGGGCGGGGTTCGTCGCCTATAGCTGG
CCGAAACCGGGCCTCGACCGGCCCGTGCCCAAGATCTCCTACGTGAAGGGTTTCGCGCCCTGGGGCTGGATCATCGGGAC
CGGGATCTACGCGGACGACACCGCCGATCAGGTGCGCCCGGCCCTCCAACGCCTCCTCGCCGGCGCCGCCCTCGCCGCGC
TGGTGATCGCCGGCCTGGCGACGCTGATCGGCCGGGGCGTTGCCCGCCCGATCCGGGCGCTGACCGACACGATGGACGGC
CTCGCCGGGGGAGACCTCGAGCGGGCGGTGCCCCGCTCCGGCGGTACCGAGGAGATCGGCCGGATGGCCGCCGCCGTGCA
GGTGTTCAAGGACAACCTGATCCGCACCCGGCAGCTCGAGGCGGAGACGGCGCGGGCCCGCGCCTCGGCCGAGGCGCAGC
GCCGTGCCGGCATGCGCCAGATGGCGGACGGTTTCGAGGCCGCGGTCGGGGGCATCATCGGGCAGGTCTCGGCCGCGGCC
ACCGAGCTGCAGGCCACCGCCGGTTCCATGTCGGGCTTGGCCGGCCAGACCTCGATCCAGTCCCGCACGGTCGCGGCGGC
GGCCGAGGAAGCGGCCGCCAACGTCGGCACGGTCGCGGCGGCCGCCGAGGAACTGGGCGCTTCGGTGCAGGAGATCGGCC
GGCAGGTCCAGGGCTCGGCCGGCCTCGCCCAGGCGGCGGTCGGCGAGGCCGACCGGACCGGCGCGCTGGTGCAGGAGCTC
AGCGCGGCCGTGACGCGGATCGGCGACGTCGCCGGGCTGATCGCCGCGATCGCCGGCCAGACGAACCTGCTCGCGCTCAA
CGCCGCCATCGAGGCGGCCCGTGCCGGCACGGCCGGGCGCGGCTTCGCGGTCGTGGCCTCCGAGGTGAAGGCCCTGGCCG
AGCAGACCGCCAGGGCGACGGCGGAGATCTCGGGGCAGATCGCGCGGGTTCAGGGCGTGACCGGGCAGGCGGTCGGCGCG
GTCGGCGCGATCACGGCGCGCATCCGCGAGATCGACGCCGTGGCGACCTCGATCGCGGCCGCCGTGGAGCAGCAGGGCGC
GGCCACCCAGGAGATCGTGCGCAACGTCGGGGAGGCCGCGCAGGGGACCGGGGCGGTGACCGGCACGATCGCGCGCGTGG
CGGGTGCCGCCGGGGAGACGGGCGCGGCGGCGGGGCAGGTGCTCGGCGCGGCCTCCGCGCTGTCGCGTCAGTCCGAGCAC
CTCGCCGCCGAGGTCGGGCGCTTCCTCGCGACGGTGCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
TAACTTCTTATTACCTGTGATGACATAAGCCGCCTTCGCCGACCGAACTGCGTTCCGGCCTGCCGCTTATAGCCTCCACG
AAGCTCTCCCCCTCTCGCGC

Downstream 100 bases:

>100_bases
GCCGCGGGCGCGGCCCCGCGCGGGACCGCGCCCGGGGTTTTGCACGCCGAAATTTTCGTCTCCCGCGGGCGCGGCGGCCA
GCAGCAACGATCCCGGCCGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MHPASDAAALRRDARIPMTLRIGTRLQLITAMALLGMAVLIGLAAWDLSRVIGDARALQTRNLVEAAHGALAYFEGEERA
GRMSRAAAQAAAIAEIRGLHYAGSEYFWIQDMQPRMLLHPKDALIGQDVGGLTDPAGKHLFVAMVEQVRRAGAGFVAYSW
PKPGLDRPVPKISYVKGFAPWGWIIGTGIYADDTADQVRPALQRLLAGAALAALVIAGLATLIGRGVARPIRALTDTMDG
LAGGDLERAVPRSGGTEEIGRMAAAVQVFKDNLIRTRQLEAETARARASAEAQRRAGMRQMADGFEAAVGGIIGQVSAAA
TELQATAGSMSGLAGQTSIQSRTVAAAAEEAAANVGTVAAAAEELGASVQEIGRQVQGSAGLAQAAVGEADRTGALVQEL
SAAVTRIGDVAGLIAAIAGQTNLLALNAAIEAARAGTAGRGFAVVASEVKALAEQTARATAEISGQIARVQGVTGQAVGA
VGAITARIREIDAVATSIAAAVEQQGAATQEIVRNVGEAAQGTGAVTGTIARVAGAAGETGAAAGQVLGAASALSRQSEH
LAAEVGRFLATVRAA

Sequences:

>Translated_575_residues
MHPASDAAALRRDARIPMTLRIGTRLQLITAMALLGMAVLIGLAAWDLSRVIGDARALQTRNLVEAAHGALAYFEGEERA
GRMSRAAAQAAAIAEIRGLHYAGSEYFWIQDMQPRMLLHPKDALIGQDVGGLTDPAGKHLFVAMVEQVRRAGAGFVAYSW
PKPGLDRPVPKISYVKGFAPWGWIIGTGIYADDTADQVRPALQRLLAGAALAALVIAGLATLIGRGVARPIRALTDTMDG
LAGGDLERAVPRSGGTEEIGRMAAAVQVFKDNLIRTRQLEAETARARASAEAQRRAGMRQMADGFEAAVGGIIGQVSAAA
TELQATAGSMSGLAGQTSIQSRTVAAAAEEAAANVGTVAAAAEELGASVQEIGRQVQGSAGLAQAAVGEADRTGALVQEL
SAAVTRIGDVAGLIAAIAGQTNLLALNAAIEAARAGTAGRGFAVVASEVKALAEQTARATAEISGQIARVQGVTGQAVGA
VGAITARIREIDAVATSIAAAVEQQGAATQEIVRNVGEAAQGTGAVTGTIARVAGAAGETGAAAGQVLGAASALSRQSEH
LAAEVGRFLATVRAA
>Mature_575_residues
MHPASDAAALRRDARIPMTLRIGTRLQLITAMALLGMAVLIGLAAWDLSRVIGDARALQTRNLVEAAHGALAYFEGEERA
GRMSRAAAQAAAIAEIRGLHYAGSEYFWIQDMQPRMLLHPKDALIGQDVGGLTDPAGKHLFVAMVEQVRRAGAGFVAYSW
PKPGLDRPVPKISYVKGFAPWGWIIGTGIYADDTADQVRPALQRLLAGAALAALVIAGLATLIGRGVARPIRALTDTMDG
LAGGDLERAVPRSGGTEEIGRMAAAVQVFKDNLIRTRQLEAETARARASAEAQRRAGMRQMADGFEAAVGGIIGQVSAAA
TELQATAGSMSGLAGQTSIQSRTVAAAAEEAAANVGTVAAAAEELGASVQEIGRQVQGSAGLAQAAVGEADRTGALVQEL
SAAVTRIGDVAGLIAAIAGQTNLLALNAAIEAARAGTAGRGFAVVASEVKALAEQTARATAEISGQIARVQGVTGQAVGA
VGAITARIREIDAVATSIAAAVEQQGAATQEIVRNVGEAAQGTGAVTGTIARVAGAAGETGAAAGQVLGAASALSRQSEH
LAAEVGRFLATVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=458, Percent_Identity=26.6375545851528, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788194, Length=250, Percent_Identity=33.2, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI2367378, Length=271, Percent_Identity=30.6273062730627, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788195, Length=148, Percent_Identity=41.2162162162162, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=185, Percent_Identity=34.5945945945946, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58445; Mature: 58445

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPASDAAALRRDARIPMTLRIGTRLQLITAMALLGMAVLIGLAAWDLSRVIGDARALQT
CCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNLVEAAHGALAYFEGEERAGRMSRAAAQAAAIAEIRGLHYAGSEYFWIQDMQPRMLLHP
HHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCEEECC
KDALIGQDVGGLTDPAGKHLFVAMVEQVRRAGAGFVAYSWPKPGLDRPVPKISYVKGFAP
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHCCCC
WGWIIGTGIYADDTADQVRPALQRLLAGAALAALVIAGLATLIGRGVARPIRALTDTMDG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAGGDLERAVPRSGGTEEIGRMAAAVQVFKDNLIRTRQLEAETARARASAEAQRRAGMRQ
CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADGFEAAVGGIIGQVSAAATELQATAGSMSGLAGQTSIQSRTVAAAAEEAAANVGTVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAEELGASVQEIGRQVQGSAGLAQAAVGEADRTGALVQELSAAVTRIGDVAGLIAAIAGQ
HHHHHCCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNLLALNAAIEAARAGTAGRGFAVVASEVKALAEQTARATAEISGQIARVQGVTGQAVGA
CCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHH
VGAITARIREIDAVATSIAAAVEQQGAATQEIVRNVGEAAQGTGAVTGTIARVAGAAGET
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
GAAAGQVLGAASALSRQSEHLAAEVGRFLATVRAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPASDAAALRRDARIPMTLRIGTRLQLITAMALLGMAVLIGLAAWDLSRVIGDARALQT
CCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNLVEAAHGALAYFEGEERAGRMSRAAAQAAAIAEIRGLHYAGSEYFWIQDMQPRMLLHP
HHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCEEECC
KDALIGQDVGGLTDPAGKHLFVAMVEQVRRAGAGFVAYSWPKPGLDRPVPKISYVKGFAP
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHCCCC
WGWIIGTGIYADDTADQVRPALQRLLAGAALAALVIAGLATLIGRGVARPIRALTDTMDG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAGGDLERAVPRSGGTEEIGRMAAAVQVFKDNLIRTRQLEAETARARASAEAQRRAGMRQ
CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADGFEAAVGGIIGQVSAAATELQATAGSMSGLAGQTSIQSRTVAAAAEEAAANVGTVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAEELGASVQEIGRQVQGSAGLAQAAVGEADRTGALVQELSAAVTRIGDVAGLIAAIAGQ
HHHHHCCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNLLALNAAIEAARAGTAGRGFAVVASEVKALAEQTARATAEISGQIARVQGVTGQAVGA
CCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHH
VGAITARIREIDAVATSIAAAVEQQGAATQEIVRNVGEAAQGTGAVTGTIARVAGAAGET
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
GAAAGQVLGAASALSRQSEHLAAEVGRFLATVRAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]