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The map label for this gene is flhA [H]

Identifier: 170748118

GI number: 170748118

Start: 1808252

End: 1810342

Strand: Reverse

Name: flhA [H]

Synonym: Mrad2831_1700

Alternate gene names: 170748118

Gene position: 1810342-1808252 (Counterclockwise)

Preceding gene: 170748119

Following gene: 170748117

Centisome position: 29.79

GC content: 68.44

Gene sequence:

>2091_bases
GTGGCAGCGGCCGTACAAGCGCTCGCGCCGGAGGGCAGAGTTCGGCGGGATATCTGGTTCGCGGTCGGGATCATCGCGAT
CCTCGCGGTCCTGTTCCTGCCTGTGCCGGCGGTGCTGATCGACATCGGACTGGCGCTGTCCATCGCCCTGTCCGTGCTGA
TCCTGATGGTGGCGCTCTGGATCCAGAAGCCGCTCGAGTTCTCGTCGTTCCCGACGATCCTGCTGATCGCGACCCTCCTG
CGCCTGGCGCTGGGGATCGCGACGACCCGGCTGATCCTGTCGAACGGCGATGCCGGCATCGACGCCGCCGGCCACGTCAT
CCAGGGCTTCTCGCAGTTCGTCATGAGCGGCGACTTCGTGATCGGCCTGGTGGTCTTCGCCATCCTGATCACCGTGAACT
TCCTGGTGATCACCAAGGGCGCGACCCGCATCGCCGAGGTCGGCGCCCGCTTCACCCTGGACGCGATCCCGGGCAAGCAG
ATGGCGATCGACGCGGATCTCTCGGCCGGCCTCATCGACGACAAGGAGGCGCAGCGGCGGCGGCGCGAGCTCGAGGAGGA
GAGCGCGTTCTTCGGCTCCATGGACGGCGCCTCGAAATTCGTGCGCGGCGAGGCGATCGCGAGCCTGATCGTCATCGCGG
TCAACATCTTCGGCGGCATCATCATCGGCGTCACCCGCCACGGCCTGCCGCTGGCCAAGGCGGCCGACGTCTTCACCAAG
CTCTCGGTCGGCGACGGTCTGGTCTCGCAGATCCCCGCGCTGATCGTGTCGCTCGCCGCGGGCCTGCTGGTCTCCAAGGG
GGGCACCCGCGGCACGGCCGAGCAGGCGGTCCTCGGGCAGCTCGGCGCCTATCCGCGGGCGCTGTTCGTGGCCGCCGGGC
TGATGCTGGTCTTCGCGATCCTGCCCGGGATGCCGTTCGTGCCCTTCGCGGTCCTGAGCGCCCTGATGGGCACGATCGCC
TACCTGATTCCCCGGCGCCTCGCCGAGGTGCAGTCGAAGGCCGACGCCGAGGCGCGGGCGAAGGAGCGGCAGCTCCTCCT
GGAACGCCAGGACAGCGAGGCCGTGAAGGAATCGCTGAAGACCGCCGAGATCGAGCTCCGCCTCGGCAAGCACTTGGCGG
TGCAGATGCAGCCCGCACAGCAGGAGCTCGCCCACCGGGTCGGCCGGATGCGGCGGAAATTCGCCCAGCAATACGGGTTC
GTGGTTCCGGAGATCCGGCTCGTCGAGTCGGCCACCGTCCCGAGCAAGAGCTACGAGATCGCGATCCACGGGACCGTCAT
CGCCGCGCAGCAGGTCCGTCCCGGCGAGATGATGATCGTCGTGGGCGACGGGCCGCTGCCGACCGTGACCGGCGAGGAGG
TGCGCGAGCCGGCCTTCGGCATGCGGGCCGTGTGGGTGCCGGACGCCTACGCGCCGGAGGCCCGGCGCGAGGGCTTCAGC
CCGATCGACTGGCACGCCGTCATGCTGACCCATGTCAGCGAGGTCATCCGCAACAACCTGCCGCAGCTGCTCTCCTACAA
AGATATGCGGATGCTCATCGACCGCCTGGATGCCGAGTACAAGCGGCTGGTCGACGAGATCTGTCCGTCGCAGATCTCGT
ATTCGGGCCTGCAGGCCGTGCTCAAGCTGCTGCTCGCCGAGCGGGTCTCGATCCGGAACCTGCACCTGATCATCGAGGCC
GTCGCCGAGATCGTCCCGCACGCGCGGCGGGCGGAGCAGATCGCCGAGCATGTCCGCCTGCGGATCGCCCAGCAGATCTG
CGGCGATCTCGCCGAGAACGGGGTCCTCCACGTCCTGCGGCTCGGCAGCCGCTGGGATCTCACCTTCCATCAGGGACTCA
AGCGCGACGCCAAGGGCGACGTGGTCGAGGTGGATATCGATCCGCGCCTGATCGAGCAGTTCGGCGTCGAGGCCTCGGAG
GCGATCCGCACCCACATGAAGACGGCGCACCGATTCGCCCTGGTCACCGCGCCGGAGGTCCGCAGCTACGTGCGGATGAT
CATCGAGCGGCTGTTCCCGACGGTCGCGGTCCTGTCGCACGTGGAGATCGCGCGCGGGGTCGAGATCAAGTCGCTCGGCA
CGATCTCCTGA

Upstream 100 bases:

>100_bases
AGCCGGCGGAGCCCGACGGCGAGCGCCCGCCACGGCCGGCGCAATCCAGGCGCAAGCTTGGTGATCCAGAAGCACAGGCG
ATACGGAGAGGGGTGAGAGC

Downstream 100 bases:

>100_bases
CAGCCGATGAGTCCCGACACGATCCTGGGCGTCTTCGTCATCTTCTGCCGTGTCGGCGGCTGCCTGCTGGTCGCTCCGGG
ACTCTCCAGCGCGCGGGTGG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MAAAVQALAPEGRVRRDIWFAVGIIAILAVLFLPVPAVLIDIGLALSIALSVLILMVALWIQKPLEFSSFPTILLIATLL
RLALGIATTRLILSNGDAGIDAAGHVIQGFSQFVMSGDFVIGLVVFAILITVNFLVITKGATRIAEVGARFTLDAIPGKQ
MAIDADLSAGLIDDKEAQRRRRELEEESAFFGSMDGASKFVRGEAIASLIVIAVNIFGGIIIGVTRHGLPLAKAADVFTK
LSVGDGLVSQIPALIVSLAAGLLVSKGGTRGTAEQAVLGQLGAYPRALFVAAGLMLVFAILPGMPFVPFAVLSALMGTIA
YLIPRRLAEVQSKADAEARAKERQLLLERQDSEAVKESLKTAEIELRLGKHLAVQMQPAQQELAHRVGRMRRKFAQQYGF
VVPEIRLVESATVPSKSYEIAIHGTVIAAQQVRPGEMMIVVGDGPLPTVTGEEVREPAFGMRAVWVPDAYAPEARREGFS
PIDWHAVMLTHVSEVIRNNLPQLLSYKDMRMLIDRLDAEYKRLVDEICPSQISYSGLQAVLKLLLAERVSIRNLHLIIEA
VAEIVPHARRAEQIAEHVRLRIAQQICGDLAENGVLHVLRLGSRWDLTFHQGLKRDAKGDVVEVDIDPRLIEQFGVEASE
AIRTHMKTAHRFALVTAPEVRSYVRMIIERLFPTVAVLSHVEIARGVEIKSLGTIS

Sequences:

>Translated_696_residues
MAAAVQALAPEGRVRRDIWFAVGIIAILAVLFLPVPAVLIDIGLALSIALSVLILMVALWIQKPLEFSSFPTILLIATLL
RLALGIATTRLILSNGDAGIDAAGHVIQGFSQFVMSGDFVIGLVVFAILITVNFLVITKGATRIAEVGARFTLDAIPGKQ
MAIDADLSAGLIDDKEAQRRRRELEEESAFFGSMDGASKFVRGEAIASLIVIAVNIFGGIIIGVTRHGLPLAKAADVFTK
LSVGDGLVSQIPALIVSLAAGLLVSKGGTRGTAEQAVLGQLGAYPRALFVAAGLMLVFAILPGMPFVPFAVLSALMGTIA
YLIPRRLAEVQSKADAEARAKERQLLLERQDSEAVKESLKTAEIELRLGKHLAVQMQPAQQELAHRVGRMRRKFAQQYGF
VVPEIRLVESATVPSKSYEIAIHGTVIAAQQVRPGEMMIVVGDGPLPTVTGEEVREPAFGMRAVWVPDAYAPEARREGFS
PIDWHAVMLTHVSEVIRNNLPQLLSYKDMRMLIDRLDAEYKRLVDEICPSQISYSGLQAVLKLLLAERVSIRNLHLIIEA
VAEIVPHARRAEQIAEHVRLRIAQQICGDLAENGVLHVLRLGSRWDLTFHQGLKRDAKGDVVEVDIDPRLIEQFGVEASE
AIRTHMKTAHRFALVTAPEVRSYVRMIIERLFPTVAVLSHVEIARGVEIKSLGTIS
>Mature_695_residues
AAAVQALAPEGRVRRDIWFAVGIIAILAVLFLPVPAVLIDIGLALSIALSVLILMVALWIQKPLEFSSFPTILLIATLLR
LALGIATTRLILSNGDAGIDAAGHVIQGFSQFVMSGDFVIGLVVFAILITVNFLVITKGATRIAEVGARFTLDAIPGKQM
AIDADLSAGLIDDKEAQRRRRELEEESAFFGSMDGASKFVRGEAIASLIVIAVNIFGGIIIGVTRHGLPLAKAADVFTKL
SVGDGLVSQIPALIVSLAAGLLVSKGGTRGTAEQAVLGQLGAYPRALFVAAGLMLVFAILPGMPFVPFAVLSALMGTIAY
LIPRRLAEVQSKADAEARAKERQLLLERQDSEAVKESLKTAEIELRLGKHLAVQMQPAQQELAHRVGRMRRKFAQQYGFV
VPEIRLVESATVPSKSYEIAIHGTVIAAQQVRPGEMMIVVGDGPLPTVTGEEVREPAFGMRAVWVPDAYAPEARREGFSP
IDWHAVMLTHVSEVIRNNLPQLLSYKDMRMLIDRLDAEYKRLVDEICPSQISYSGLQAVLKLLLAERVSIRNLHLIIEAV
AEIVPHARRAEQIAEHVRLRIAQQICGDLAENGVLHVLRLGSRWDLTFHQGLKRDAKGDVVEVDIDPRLIEQFGVEASEA
IRTHMKTAHRFALVTAPEVRSYVRMIIERLFPTVAVLSHVEIARGVEIKSLGTIS

Specific function: Required for formation of the rod structure of the flagellar apparatus. May constitute the export apparatus of flagellin. The flagellum is required to cause a persistent disease in a murine model of infection [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=679, Percent_Identity=35.7879234167894, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75717; Mature: 75586

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAVQALAPEGRVRRDIWFAVGIIAILAVLFLPVPAVLIDIGLALSIALSVLILMVALW
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQKPLEFSSFPTILLIATLLRLALGIATTRLILSNGDAGIDAAGHVIQGFSQFVMSGDFV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHH
IGLVVFAILITVNFLVITKGATRIAEVGARFTLDAIPGKQMAIDADLSAGLIDDKEAQRR
HHHHHHHHHHHHHHHHEECCHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCHHHHHH
RRELEEESAFFGSMDGASKFVRGEAIASLIVIAVNIFGGIIIGVTRHGLPLAKAADVFTK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LSVGDGLVSQIPALIVSLAAGLLVSKGGTRGTAEQAVLGQLGAYPRALFVAAGLMLVFAI
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LPGMPFVPFAVLSALMGTIAYLIPRRLAEVQSKADAEARAKERQLLLERQDSEAVKESLK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
TAEIELRLGKHLAVQMQPAQQELAHRVGRMRRKFAQQYGFVVPEIRLVESATVPSKSYEI
HHHHHEEECCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEE
AIHGTVIAAQQVRPGEMMIVVGDGPLPTVTGEEVREPAFGMRAVWVPDAYAPEARREGFS
EEEEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCEEEECCCCCCCHHHHCCCC
PIDWHAVMLTHVSEVIRNNLPQLLSYKDMRMLIDRLDAEYKRLVDEICPSQISYSGLQAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHH
LKLLLAERVSIRNLHLIIEAVAEIVPHARRAEQIAEHVRLRIAQQICGDLAENGVLHVLR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHC
LGSRWDLTFHQGLKRDAKGDVVEVDIDPRLIEQFGVEASEAIRTHMKTAHRFALVTAPEV
CCCCCCCHHHHCCCCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHEEEEECHHH
RSYVRMIIERLFPTVAVLSHVEIARGVEIKSLGTIS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AAAVQALAPEGRVRRDIWFAVGIIAILAVLFLPVPAVLIDIGLALSIALSVLILMVALW
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQKPLEFSSFPTILLIATLLRLALGIATTRLILSNGDAGIDAAGHVIQGFSQFVMSGDFV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHH
IGLVVFAILITVNFLVITKGATRIAEVGARFTLDAIPGKQMAIDADLSAGLIDDKEAQRR
HHHHHHHHHHHHHHHHEECCHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCHHHHHH
RRELEEESAFFGSMDGASKFVRGEAIASLIVIAVNIFGGIIIGVTRHGLPLAKAADVFTK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LSVGDGLVSQIPALIVSLAAGLLVSKGGTRGTAEQAVLGQLGAYPRALFVAAGLMLVFAI
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LPGMPFVPFAVLSALMGTIAYLIPRRLAEVQSKADAEARAKERQLLLERQDSEAVKESLK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
TAEIELRLGKHLAVQMQPAQQELAHRVGRMRRKFAQQYGFVVPEIRLVESATVPSKSYEI
HHHHHEEECCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEE
AIHGTVIAAQQVRPGEMMIVVGDGPLPTVTGEEVREPAFGMRAVWVPDAYAPEARREGFS
EEEEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCEEEECCCCCCCHHHHCCCC
PIDWHAVMLTHVSEVIRNNLPQLLSYKDMRMLIDRLDAEYKRLVDEICPSQISYSGLQAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHH
LKLLLAERVSIRNLHLIIEAVAEIVPHARRAEQIAEHVRLRIAQQICGDLAENGVLHVLR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHC
LGSRWDLTFHQGLKRDAKGDVVEVDIDPRLIEQFGVEASEAIRTHMKTAHRFALVTAPEV
CCCCCCCHHHHCCCCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHEEEEECHHH
RSYVRMIIERLFPTVAVLSHVEIARGVEIKSLGTIS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]