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The map label for this gene is pabB [H]

Identifier: 170748056

GI number: 170748056

Start: 1747178

End: 1748551

Strand: Reverse

Name: pabB [H]

Synonym: Mrad2831_1638

Alternate gene names: 170748056

Gene position: 1748551-1747178 (Counterclockwise)

Preceding gene: 170748060

Following gene: 170748055

Centisome position: 28.77

GC content: 73.94

Gene sequence:

>1374_bases
ATGTGGACCCGAGAGATCCCCTTCATCGATCCCGTCGCGGCGGCGGCCCGGCTGCGCGCCCTGCCCGGGCTCGCCTTCCT
CGACAGCGCCATGCGGCACGACCCGCTGGGGCGGCACTCGATCGTGGCCGCCGACCCGTTCGCGCGGTTCCGCTACCGCG
ACGGGCGCGCGACCCTCGACGGGCGACCGGTGGCGGGCGGCCCGATGGCGGCGCTCCGGGCCTGCCTCGAACCCTACCGG
CTCGAGCCCGGGCCGGAACCGTTCCCCGGCGGGGCGATCGGGTACCTGGCCTACGACCTCGGCGCGGCGCTGGAGCGGGT
GGCGGCGCCGGCCCGGCGGGCGGGGCTCACCGACGACATCGCGCTGAACCTCTACGACACGGCCCTGGTCGTCGACCACG
CCGCCGGCACGGCCCGGCTGGTCGCCACGGGTTTCCCGGAGACCGCGCCGGACGCGCGGCGGGCCCGCGCGGAGGCGCGG
CTCGCCGGCTTCGCCGACCTGCTCGGCGGCGCGGAGCCGCCGGTCCCGGCCGCAGCCCGGCCGGCCCAACCGCTCGCGTG
GCGCTCGAACTTCGACCGCCAAAGCTATGAAGAGGCTGTCGAAAAAGTCCGCGCATACATTCGCGCCGGCGACATCTACC
AGGCCAATATCGCCCAGCGCTTCGTCGCCGACCTGCCGGCCGGCTTCGACCCGTTCGCCCTCTACCGGCGGCTGCGCGAG
ACCAATCCGGCGACCTTCGGGGCCTACCTGGAACAGGAGGGCCTGACCGTGGCCTCGTCATCGCCGGAGCGGTTCATCCG
CCTCGACGGCCGGCACGTGGAGACGCGCCCGATCAAGGGCACCGCCCGCCGCCTCGACGACCCGGTGGCCGACCGGGCGG
CGGCCGAGGCGCTGCAGGCCAGCGTCAAGGAGCGGGCCGAGAACGTCATGATCGTCGACCTGCTGCGCAACGACCTGTCG
CGGGTCTGCGCGCCGGGCAGCGTCGCCGTGCCGACCCTGTGCGGGCTGGAGACCTACGCCAACGTCCACCATCTGGTGTC
GGTGGTGACCGGAGACCTCCGCGACGGGCTCGACGCCCTCGACCTCCTGGAAGGGACCTTCCCGGGCGGCTCGATCACGG
GCGCCCCGAAGATCCGCGCCATGGACATCATCACCGAGATCGAGGGCGACGCGCGGGAACTCTACTGCGGCGCCATCGGC
CGGATCGGCTTCGACGGGGCGCTCGACACGTCGATCGCGATCCGCACCGTGTTCATGGACGCGCACCAGGCGGTCCTGCA
GGCCGGGGGCGGGGTGACCCTGCTGTCGGAGCCGGGCCCGGAATACGACGAGACCCTGGCCAAGGCCGCCCGCGTCTTCG
AGGCCTTCGCATGA

Upstream 100 bases:

>100_bases
GCGGCGGGGCCTGCGTGGAACTGCCGCTTCCCCCGCGGCATCGCCTGTGCGACGGCAGCGGACGACGCACAGCCCGAGGA
TAACGGCCCCGAACCCGGTC

Downstream 100 bases:

>100_bases
TCCTCGTCCTCGACAATTACGACTCGTTCGTCTTCAACGTCGTCCGCTACCTGGAGGAGCTCGGCGAGACGGTCCGGGTC
GTGCGCAACGACGCGCTGGA

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MWTREIPFIDPVAAAARLRALPGLAFLDSAMRHDPLGRHSIVAADPFARFRYRDGRATLDGRPVAGGPMAALRACLEPYR
LEPGPEPFPGGAIGYLAYDLGAALERVAAPARRAGLTDDIALNLYDTALVVDHAAGTARLVATGFPETAPDARRARAEAR
LAGFADLLGGAEPPVPAAARPAQPLAWRSNFDRQSYEEAVEKVRAYIRAGDIYQANIAQRFVADLPAGFDPFALYRRLRE
TNPATFGAYLEQEGLTVASSSPERFIRLDGRHVETRPIKGTARRLDDPVADRAAAEALQASVKERAENVMIVDLLRNDLS
RVCAPGSVAVPTLCGLETYANVHHLVSVVTGDLRDGLDALDLLEGTFPGGSITGAPKIRAMDIITEIEGDARELYCGAIG
RIGFDGALDTSIAIRTVFMDAHQAVLQAGGGVTLLSEPGPEYDETLAKAARVFEAFA

Sequences:

>Translated_457_residues
MWTREIPFIDPVAAAARLRALPGLAFLDSAMRHDPLGRHSIVAADPFARFRYRDGRATLDGRPVAGGPMAALRACLEPYR
LEPGPEPFPGGAIGYLAYDLGAALERVAAPARRAGLTDDIALNLYDTALVVDHAAGTARLVATGFPETAPDARRARAEAR
LAGFADLLGGAEPPVPAAARPAQPLAWRSNFDRQSYEEAVEKVRAYIRAGDIYQANIAQRFVADLPAGFDPFALYRRLRE
TNPATFGAYLEQEGLTVASSSPERFIRLDGRHVETRPIKGTARRLDDPVADRAAAEALQASVKERAENVMIVDLLRNDLS
RVCAPGSVAVPTLCGLETYANVHHLVSVVTGDLRDGLDALDLLEGTFPGGSITGAPKIRAMDIITEIEGDARELYCGAIG
RIGFDGALDTSIAIRTVFMDAHQAVLQAGGGVTLLSEPGPEYDETLAKAARVFEAFA
>Mature_457_residues
MWTREIPFIDPVAAAARLRALPGLAFLDSAMRHDPLGRHSIVAADPFARFRYRDGRATLDGRPVAGGPMAALRACLEPYR
LEPGPEPFPGGAIGYLAYDLGAALERVAAPARRAGLTDDIALNLYDTALVVDHAAGTARLVATGFPETAPDARRARAEAR
LAGFADLLGGAEPPVPAAARPAQPLAWRSNFDRQSYEEAVEKVRAYIRAGDIYQANIAQRFVADLPAGFDPFALYRRLRE
TNPATFGAYLEQEGLTVASSSPERFIRLDGRHVETRPIKGTARRLDDPVADRAAAEALQASVKERAENVMIVDLLRNDLS
RVCAPGSVAVPTLCGLETYANVHHLVSVVTGDLRDGLDALDLLEGTFPGGSITGAPKIRAMDIITEIEGDARELYCGAIG
RIGFDGALDTSIAIRTVFMDAHQAVLQAGGGVTLLSEPGPEYDETLAKAARVFEAFA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=450, Percent_Identity=38.8888888888889, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1787518, Length=374, Percent_Identity=35.8288770053476, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786809, Length=266, Percent_Identity=26.6917293233083, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=33.0296127562642, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324361, Length=409, Percent_Identity=26.4058679706601, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 48920; Mature: 48920

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTREIPFIDPVAAAARLRALPGLAFLDSAMRHDPLGRHSIVAADPFARFRYRDGRATLD
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCHHHHEECCCCCCCC
GRPVAGGPMAALRACLEPYRLEPGPEPFPGGAIGYLAYDLGAALERVAAPARRAGLTDDI
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ALNLYDTALVVDHAAGTARLVATGFPETAPDARRARAEARLAGFADLLGGAEPPVPAAAR
EEEEEHHEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PAQPLAWRSNFDRQSYEEAVEKVRAYIRAGDIYQANIAQRFVADLPAGFDPFALYRRLRE
CCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TNPATFGAYLEQEGLTVASSSPERFIRLDGRHVETRPIKGTARRLDDPVADRAAAEALQA
CCCCHHHHHHHHCCCEEECCCCCCEEEECCCEEECCCCCHHHHHCCCHHHHHHHHHHHHH
SVKERAENVMIVDLLRNDLSRVCAPGSVAVPTLCGLETYANVHHLVSVVTGDLRDGLDAL
HHHHHHCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DLLEGTFPGGSITGAPKIRAMDIITEIEGDARELYCGAIGRIGFDGALDTSIAIRTVFMD
HHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AHQAVLQAGGGVTLLSEPGPEYDETLAKAARVFEAFA
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWTREIPFIDPVAAAARLRALPGLAFLDSAMRHDPLGRHSIVAADPFARFRYRDGRATLD
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCHHHHEECCCCCCCC
GRPVAGGPMAALRACLEPYRLEPGPEPFPGGAIGYLAYDLGAALERVAAPARRAGLTDDI
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ALNLYDTALVVDHAAGTARLVATGFPETAPDARRARAEARLAGFADLLGGAEPPVPAAAR
EEEEEHHEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PAQPLAWRSNFDRQSYEEAVEKVRAYIRAGDIYQANIAQRFVADLPAGFDPFALYRRLRE
CCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TNPATFGAYLEQEGLTVASSSPERFIRLDGRHVETRPIKGTARRLDDPVADRAAAEALQA
CCCCHHHHHHHHCCCEEECCCCCCEEEECCCEEECCCCCHHHHHCCCHHHHHHHHHHHHH
SVKERAENVMIVDLLRNDLSRVCAPGSVAVPTLCGLETYANVHHLVSVVTGDLRDGLDAL
HHHHHHCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DLLEGTFPGGSITGAPKIRAMDIITEIEGDARELYCGAIGRIGFDGALDTSIAIRTVFMD
HHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AHQAVLQAGGGVTLLSEPGPEYDETLAKAARVFEAFA
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]