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The map label for this gene is pabA [H]

Identifier: 170748055

GI number: 170748055

Start: 1746567

End: 1747181

Strand: Reverse

Name: pabA [H]

Synonym: Mrad2831_1637

Alternate gene names: 170748055

Gene position: 1747181-1746567 (Counterclockwise)

Preceding gene: 170748056

Following gene: 170748054

Centisome position: 28.75

GC content: 73.01

Gene sequence:

>615_bases
ATGATCCTCGTCCTCGACAATTACGACTCGTTCGTCTTCAACGTCGTCCGCTACCTGGAGGAGCTCGGCGAGACGGTCCG
GGTCGTGCGCAACGACGCGCTGGACGTCCCCGGCATCCGGGCGCTCGAACCGGAGGCCCTGGTGGTCTCGCCCGGGCCCT
GCACCCCCGCGGAGGCCGGGATCTCCCTGCCGGCGATCCGGGAGCTGTCGGGCGCGGTGCCGATCCTCGGCGTCTGCCTC
GGCCACCAGGCGATCGGCGCGGCCTTCGGCGGCACGGTCGCGCGGGCGCAGCGGCCCCTGCACGGGCAGATGACGCCGAT
CGACCACGCGGGCCAGCGCCTGTTCGCCGGGCTGCCGGCGCCGATGCCGGTGGGACGCTACCACTCGCTGGTGGTCACCC
CCGGCCCCGACATGGCGCGGCACCTCTCGGTCGACGCCGTCTCGCAGGAGGGGGAGGTGATGGCGCTGTCGCACCGGACC
CACCCGACCTACGGCATCCAGTTCCACCCGGAATCGGTCCTGACCGAGGGCGGCCACGCCCTGTTCGCCAATTTCCTGGG
ACTGGCCCGCGCGTGGCGGCAGAGACCGGAGGGGCGCCGCGATGCTGTGGCGTGA

Upstream 100 bases:

>100_bases
CGGTCCTGCAGGCCGGGGGCGGGGTGACCCTGCTGTCGGAGCCGGGCCCGGAATACGACGAGACCCTGGCCAAGGCCGCC
CGCGTCTTCGAGGCCTTCGC

Downstream 100 bases:

>100_bases
CGGGGCGCTTCTCCCCGGGACGACCGCGCCGCTGGACCACACCGACCGCGGCCTGACGCTCGGCGACGGCCTGTTCGACA
CCGCGCTGGCGCTCGGCGGC

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MILVLDNYDSFVFNVVRYLEELGETVRVVRNDALDVPGIRALEPEALVVSPGPCTPAEAGISLPAIRELSGAVPILGVCL
GHQAIGAAFGGTVARAQRPLHGQMTPIDHAGQRLFAGLPAPMPVGRYHSLVVTPGPDMARHLSVDAVSQEGEVMALSHRT
HPTYGIQFHPESVLTEGGHALFANFLGLARAWRQRPEGRRDAVA

Sequences:

>Translated_204_residues
MILVLDNYDSFVFNVVRYLEELGETVRVVRNDALDVPGIRALEPEALVVSPGPCTPAEAGISLPAIRELSGAVPILGVCL
GHQAIGAAFGGTVARAQRPLHGQMTPIDHAGQRLFAGLPAPMPVGRYHSLVVTPGPDMARHLSVDAVSQEGEVMALSHRT
HPTYGIQFHPESVLTEGGHALFANFLGLARAWRQRPEGRRDAVA
>Mature_204_residues
MILVLDNYDSFVFNVVRYLEELGETVRVVRNDALDVPGIRALEPEALVVSPGPCTPAEAGISLPAIRELSGAVPILGVCL
GHQAIGAAFGGTVARAQRPLHGQMTPIDHAGQRLFAGLPAPMPVGRYHSLVVTPGPDMARHLSVDAVSQEGEVMALSHRT
HPTYGIQFHPESVLTEGGHALFANFLGLARAWRQRPEGRRDAVA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=54.8387096774194, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1787517, Length=200, Percent_Identity=43, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322638, Length=204, Percent_Identity=39.7058823529412, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=34.2723004694836, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21817; Mature: 21817

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLDNYDSFVFNVVRYLEELGETVRVVRNDALDVPGIRALEPEALVVSPGPCTPAEAG
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCHHHCC
ISLPAIRELSGAVPILGVCLGHQAIGAAFGGTVARAQRPLHGQMTPIDHAGQRLFAGLPA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
PMPVGRYHSLVVTPGPDMARHLSVDAVSQEGEVMALSHRTHPTYGIQFHPESVLTEGGHA
CCCCCCCEEEEEECCCCHHHHHCHHHCCCCCCEEEEECCCCCCCCEEECCHHHHHCCCHH
LFANFLGLARAWRQRPEGRRDAVA
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MILVLDNYDSFVFNVVRYLEELGETVRVVRNDALDVPGIRALEPEALVVSPGPCTPAEAG
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCHHHCC
ISLPAIRELSGAVPILGVCLGHQAIGAAFGGTVARAQRPLHGQMTPIDHAGQRLFAGLPA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
PMPVGRYHSLVVTPGPDMARHLSVDAVSQEGEVMALSHRTHPTYGIQFHPESVLTEGGHA
CCCCCCCEEEEEECCCCHHHHHCHHHCCCCCCEEEEECCCCCCCCEEECCHHHHHCCCHH
LFANFLGLARAWRQRPEGRRDAVA
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673; 2403545; 11677609 [H]