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The map label for this gene is ilvE [H]

Identifier: 170748054

GI number: 170748054

Start: 1745729

End: 1746580

Strand: Reverse

Name: ilvE [H]

Synonym: Mrad2831_1636

Alternate gene names: 170748054

Gene position: 1746580-1745729 (Counterclockwise)

Preceding gene: 170748055

Following gene: 170748053

Centisome position: 28.74

GC content: 77.11

Gene sequence:

>852_bases
ATGCTGTGGCGTGACGGGGCGCTTCTCCCCGGGACGACCGCGCCGCTGGACCACACCGACCGCGGCCTGACGCTCGGCGA
CGGCCTGTTCGACACCGCGCTGGCGCTCGGCGGCCGCGTGGCCTTCGAGGACGCCCACATCGCCCGGCTCGTGGCCTCCG
CCGACACGCTCGGGATCCCGGCCGACGCCGAGCGCATCCGTGGGGCCATGCGGGCGCTGGCCGGGCAGGGGGAGCGGCTC
GCGATCCGCACCACCCTCACCCGCGGCTCCGGCCCGCGGGGACTGAAGCCGCCGGACGCCCCGAACCCGACGCTCTTCGC
CACCGCGGCCGTGAGCACCAGGGCCGCGTCCTTCGCGCCCCTGCGCCTCTGGCCGACCGCCATCGCCCGCAACGACACCT
CCCCCGCCAGCCGCCTGAAGACGCTGGGCTATGGCGACGCGGTGCTGGCCGCCCGGGAGGCCGCCGCCGCGGGCTGCGAC
GAGGCGCTGTTCCGCAACACGCGGGGGCGCGTCGCCTGCGCGGGCACCGGCAACCTGTTCGCCCTGCTCGGCACCACCCT
GGTCACGCCGCCGCTCGGAGACGGCGTGCTCGCCGGCATCGTGCGGGCGGAGGTGCTGGGCCTCGCCGCCGGATGCGGGC
TGCGGGCCGAGGAACGGTCGCTCGGCCTGCCCGATCTCCTCGGCGCGGAGGCCGTGTTCCTGACCAATTCCCTGCGGCTC
CTGGCCCCCGTGACCGCCATCGGCGACACCGCCCTGGCCAGTGACGGCCACCCGGCGGTGGGCCGCCTCAAGGCGGCCTT
GCGCGCCCGCGCCGCCCAATCCTGCGGCGTCACGGAGGACGCTGTCGCGTGA

Upstream 100 bases:

>100_bases
TTCCACCCGGAATCGGTCCTGACCGAGGGCGGCCACGCCCTGTTCGCCAATTTCCTGGGACTGGCCCGCGCGTGGCGGCA
GAGACCGGAGGGGCGCCGCG

Downstream 100 bases:

>100_bases
CCGAGCAGGCGATCGAGACCGGGCGGCGCCGGCTGCGCTACGGGCTCGCGGCGATCTACCTGTTCATCGGCGCGGTCCAC
CTCGTGGCGACCGACGCGAT

Product: class IV aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLWRDGALLPGTTAPLDHTDRGLTLGDGLFDTALALGGRVAFEDAHIARLVASADTLGIPADAERIRGAMRALAGQGERL
AIRTTLTRGSGPRGLKPPDAPNPTLFATAAVSTRAASFAPLRLWPTAIARNDTSPASRLKTLGYGDAVLAAREAAAAGCD
EALFRNTRGRVACAGTGNLFALLGTTLVTPPLGDGVLAGIVRAEVLGLAAGCGLRAEERSLGLPDLLGAEAVFLTNSLRL
LAPVTAIGDTALASDGHPAVGRLKAALRARAAQSCGVTEDAVA

Sequences:

>Translated_283_residues
MLWRDGALLPGTTAPLDHTDRGLTLGDGLFDTALALGGRVAFEDAHIARLVASADTLGIPADAERIRGAMRALAGQGERL
AIRTTLTRGSGPRGLKPPDAPNPTLFATAAVSTRAASFAPLRLWPTAIARNDTSPASRLKTLGYGDAVLAAREAAAAGCD
EALFRNTRGRVACAGTGNLFALLGTTLVTPPLGDGVLAGIVRAEVLGLAAGCGLRAEERSLGLPDLLGAEAVFLTNSLRL
LAPVTAIGDTALASDGHPAVGRLKAALRARAAQSCGVTEDAVA
>Mature_283_residues
MLWRDGALLPGTTAPLDHTDRGLTLGDGLFDTALALGGRVAFEDAHIARLVASADTLGIPADAERIRGAMRALAGQGERL
AIRTTLTRGSGPRGLKPPDAPNPTLFATAAVSTRAASFAPLRLWPTAIARNDTSPASRLKTLGYGDAVLAAREAAAAGCD
EALFRNTRGRVACAGTGNLFALLGTTLVTPPLGDGVLAGIVRAEVLGLAAGCGLRAEERSLGLPDLLGAEAVFLTNSLRL
LAPVTAIGDTALASDGHPAVGRLKAALRARAAQSCGVTEDAVA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=244, Percent_Identity=28.6885245901639, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 28766; Mature: 28766

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWRDGALLPGTTAPLDHTDRGLTLGDGLFDTALALGGRVAFEDAHIARLVASADTLGIP
CCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCEEEECHHHHHHHHHHCCCCCCC
ADAERIRGAMRALAGQGERLAIRTTLTRGSGPRGLKPPDAPNPTLFATAAVSTRAASFAP
CCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCC
LRLWPTAIARNDTSPASRLKTLGYGDAVLAAREAAAAGCDEALFRNTRGRVACAGTGNLF
CEECHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCH
ALLGTTLVTPPLGDGVLAGIVRAEVLGLAAGCGLRAEERSLGLPDLLGAEAVFLTNSLRL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCEEEHCCCHHH
LAPVTAIGDTALASDGHPAVGRLKAALRARAAQSCGVTEDAVA
HHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MLWRDGALLPGTTAPLDHTDRGLTLGDGLFDTALALGGRVAFEDAHIARLVASADTLGIP
CCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCEEEECHHHHHHHHHHCCCCCCC
ADAERIRGAMRALAGQGERLAIRTTLTRGSGPRGLKPPDAPNPTLFATAAVSTRAASFAP
CCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCC
LRLWPTAIARNDTSPASRLKTLGYGDAVLAAREAAAAGCDEALFRNTRGRVACAGTGNLF
CEECHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCH
ALLGTTLVTPPLGDGVLAGIVRAEVLGLAAGCGLRAEERSLGLPDLLGAEAVFLTNSLRL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCEEEHCCCHHH
LAPVTAIGDTALASDGHPAVGRLKAALRARAAQSCGVTEDAVA
HHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]