Click here to switch to the map view.

The map label for this gene is lysK [H]

Identifier: 170748043

GI number: 170748043

Start: 1735047

End: 1736753

Strand: Reverse

Name: lysK [H]

Synonym: Mrad2831_1625

Alternate gene names: 170748043

Gene position: 1736753-1735047 (Counterclockwise)

Preceding gene: 170748044

Following gene: 170748042

Centisome position: 28.58

GC content: 70.88

Gene sequence:

>1707_bases
ATGCCCGCCGCTCCGCCTGCCCTGACCCTCGACGCCGACATCATCGAGGCCGCCGCCAACGCCGCCGCCTGGCCCTTCGA
GGAGGCGCGCAAGCTCGTGGCCCGGCTGGAGAAATCCGGCAAGACCGAGATCCTGTTCGAGACCGGCTACGGCCCCTCGG
GCCTGCCGCATATCGGCACGTTCGGCGAGGTCGCCCGGACCTCCATGGTGCGCCACGCCTTCCGGGTGCTCACCCGGGAC
GCGGTGCCGACCCGGCTGATCGCCTTCTCGGACGACATGGACGGGCTGCGCAAGGTTCCCGACAACGTCCCGAACCGGGA
GATGCTGGCCGCGCACCTCAACCAGCCGCTCACCCGCGTGCCGGACCCGTTCGGGACCCATGACAGCTTCGGGGCGCACA
ACAACGCCGAGCTGCGCCGCTTCCTCGACGCGTTCGGGTTCGCCTACGAGTTCCGCTCGGCGACCGAGTGCTACCGCTCG
GGCGTGTTCGACGCGACGCTGCTGCGCGTGCTGGAGCGCTACGACGCCGTGATGGAGATCATGCTGCCGTCGCTGCGGGC
CGAGCGCTCGGCGAGCTACTCGCCGTTCCTGCCGCTCCACCCGGTCACCGGCCACGTGATGCAGGTGCCGATCGACGAGG
TGAAGGCGCAGAGCGGCACGATCGTGTGGCGCGATCCCGCCACGGGCGAGCGCTACGAGACCCCGGTGACCGGCGGCCAC
GCCAAGCTGCAGTGGAAGCCCGACTGGGCGATGCGCTGGGTGGCGCTCGGCGTCGATTACGAGATGGCCGGCAAGGACCT
GATCGACTCGGTCAAGCTCTCCGCCAAGATCGCCCGGGCGCTCGGCGGCGAGCCGCCGGAGGGCTTCAATTACGAGCTGT
TCCTGGACGAGAAGGGCCAGAAGATCTCGAAGTCGAAGGGCAACGGCCTGACGATCGACGCGTGGCTCACCTACGGCACG
CCGGAATCGCTGGCCCTGTTCATGTACAACAAGCCGCGCGAGGCCAAGCGCCTGTTCTTCGACGTGATCCCCCGGCACGT
CGACGAGTATATCGGCTTCCTCGACCGCTACGCCGGCCAGGACGCGAAGCTGCGCCTCGGCAACCCGGTCTGGCACCTCC
ACGCCGGCAACCCGCCGGAGCCCGAGCGGGTCGAGGGCGCGAGCCTGACCTTCGCGATGCTGCTCAACCTCGCGGCGGTC
GCCAACACCGAGGATCCGGCGGTGCTGTGGGGCTTCATCCGCCGCTACGCGCCGCGGACCGGTCCGGAGACCCATCCGGG
CCTCGACCGGCTGGTGAAGCACGCGCTGAAGTACTTCTCGGACTTCGTGCGGCCGGCCAAGACCTACCGGGCGCCGACGC
CCGAGGAGCGGGCGGCCCTGGAGGACCTCGCGGAGACCCTCACGGAACATGCCGGCTCCACCGATCCGGAGGCGCTGCAG
GCGGCGGTCTACGAGGTCGGCCGGCGCCACTTCCCCGACACGTCCGGCAAGGCCAAGAGCCCGGACGGGCGGCCCGGCGT
GTCGCAGGCGTGGTTCACGAGCCTCTACAACGTGCTGTTCGGCGAGGCGCGCGGACCCCGGTTCGGCTCCTTCGTGGCCC
TCTACGGCGTCGACGAGACCCGCGGCCTGATCGCCGCGGCCCTGTCGGGGGCGCTCGTGGCCGAGCACGCAGCCTTCGCG
GCCGGCAAGGCGGCCCCGGTCGCGTGA

Upstream 100 bases:

>100_bases
GAACCCCGCAATGCACCGCCGGGCGTTCCGCTCCGATGCGAACCGCTCTAGGGTGCGCGCGCCCTACCCGCGTTCAGCCC
CGAAGATCACCCCCGACGAC

Downstream 100 bases:

>100_bases
GGGCGCGATGATCGTCGACGATCTCGCCGCCCTGGAGGCGATCTACAGCGCGCCCCTGGCGCCCGCCTCCACGGTGAAGG
TGGTGGCCGCGATCACGCCG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MPAAPPALTLDADIIEAAANAAAWPFEEARKLVARLEKSGKTEILFETGYGPSGLPHIGTFGEVARTSMVRHAFRVLTRD
AVPTRLIAFSDDMDGLRKVPDNVPNREMLAAHLNQPLTRVPDPFGTHDSFGAHNNAELRRFLDAFGFAYEFRSATECYRS
GVFDATLLRVLERYDAVMEIMLPSLRAERSASYSPFLPLHPVTGHVMQVPIDEVKAQSGTIVWRDPATGERYETPVTGGH
AKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSAKIARALGGEPPEGFNYELFLDEKGQKISKSKGNGLTIDAWLTYGT
PESLALFMYNKPREAKRLFFDVIPRHVDEYIGFLDRYAGQDAKLRLGNPVWHLHAGNPPEPERVEGASLTFAMLLNLAAV
ANTEDPAVLWGFIRRYAPRTGPETHPGLDRLVKHALKYFSDFVRPAKTYRAPTPEERAALEDLAETLTEHAGSTDPEALQ
AAVYEVGRRHFPDTSGKAKSPDGRPGVSQAWFTSLYNVLFGEARGPRFGSFVALYGVDETRGLIAAALSGALVAEHAAFA
AGKAAPVA

Sequences:

>Translated_568_residues
MPAAPPALTLDADIIEAAANAAAWPFEEARKLVARLEKSGKTEILFETGYGPSGLPHIGTFGEVARTSMVRHAFRVLTRD
AVPTRLIAFSDDMDGLRKVPDNVPNREMLAAHLNQPLTRVPDPFGTHDSFGAHNNAELRRFLDAFGFAYEFRSATECYRS
GVFDATLLRVLERYDAVMEIMLPSLRAERSASYSPFLPLHPVTGHVMQVPIDEVKAQSGTIVWRDPATGERYETPVTGGH
AKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSAKIARALGGEPPEGFNYELFLDEKGQKISKSKGNGLTIDAWLTYGT
PESLALFMYNKPREAKRLFFDVIPRHVDEYIGFLDRYAGQDAKLRLGNPVWHLHAGNPPEPERVEGASLTFAMLLNLAAV
ANTEDPAVLWGFIRRYAPRTGPETHPGLDRLVKHALKYFSDFVRPAKTYRAPTPEERAALEDLAETLTEHAGSTDPEALQ
AAVYEVGRRHFPDTSGKAKSPDGRPGVSQAWFTSLYNVLFGEARGPRFGSFVALYGVDETRGLIAAALSGALVAEHAAFA
AGKAAPVA
>Mature_567_residues
PAAPPALTLDADIIEAAANAAAWPFEEARKLVARLEKSGKTEILFETGYGPSGLPHIGTFGEVARTSMVRHAFRVLTRDA
VPTRLIAFSDDMDGLRKVPDNVPNREMLAAHLNQPLTRVPDPFGTHDSFGAHNNAELRRFLDAFGFAYEFRSATECYRSG
VFDATLLRVLERYDAVMEIMLPSLRAERSASYSPFLPLHPVTGHVMQVPIDEVKAQSGTIVWRDPATGERYETPVTGGHA
KLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSAKIARALGGEPPEGFNYELFLDEKGQKISKSKGNGLTIDAWLTYGTP
ESLALFMYNKPREAKRLFFDVIPRHVDEYIGFLDRYAGQDAKLRLGNPVWHLHAGNPPEPERVEGASLTFAMLLNLAAVA
NTEDPAVLWGFIRRYAPRTGPETHPGLDRLVKHALKYFSDFVRPAKTYRAPTPEERAALEDLAETLTEHAGSTDPEALQA
AVYEVGRRHFPDTSGKAKSPDGRPGVSQAWFTSLYNVLFGEARGPRFGSFVALYGVDETRGLIAAALSGALVAEHAAFAA
GKAAPVA

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 62440; Mature: 62309

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAPPALTLDADIIEAAANAAAWPFEEARKLVARLEKSGKTEILFETGYGPSGLPHIGT
CCCCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
FGEVARTSMVRHAFRVLTRDAVPTRLIAFSDDMDGLRKVPDNVPNREMLAAHLNQPLTRV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHCCCHHHC
PDPFGTHDSFGAHNNAELRRFLDAFGFAYEFRSATECYRSGVFDATLLRVLERYDAVMEI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MLPSLRAERSASYSPFLPLHPVTGHVMQVPIDEVKAQSGTIVWRDPATGERYETPVTGGH
HHHHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
AKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSAKIARALGGEPPEGFNYELFLDEKGQ
EEEEECCCHHEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
KISKSKGNGLTIDAWLTYGTPESLALFMYNKPREAKRLFFDVIPRHVDEYIGFLDRYAGQ
HHHCCCCCCEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAKLRLGNPVWHLHAGNPPEPERVEGASLTFAMLLNLAAVANTEDPAVLWGFIRRYAPRT
CCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
GPETHPGLDRLVKHALKYFSDFVRPAKTYRAPTPEERAALEDLAETLTEHAGSTDPEALQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AAVYEVGRRHFPDTSGKAKSPDGRPGVSQAWFTSLYNVLFGEARGPRFGSFVALYGVDET
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
RGLIAAALSGALVAEHAAFAAGKAAPVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PAAPPALTLDADIIEAAANAAAWPFEEARKLVARLEKSGKTEILFETGYGPSGLPHIGT
CCCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
FGEVARTSMVRHAFRVLTRDAVPTRLIAFSDDMDGLRKVPDNVPNREMLAAHLNQPLTRV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHCCCHHHC
PDPFGTHDSFGAHNNAELRRFLDAFGFAYEFRSATECYRSGVFDATLLRVLERYDAVMEI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
MLPSLRAERSASYSPFLPLHPVTGHVMQVPIDEVKAQSGTIVWRDPATGERYETPVTGGH
HHHHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
AKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSAKIARALGGEPPEGFNYELFLDEKGQ
EEEEECCCHHEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
KISKSKGNGLTIDAWLTYGTPESLALFMYNKPREAKRLFFDVIPRHVDEYIGFLDRYAGQ
HHHCCCCCCEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAKLRLGNPVWHLHAGNPPEPERVEGASLTFAMLLNLAAVANTEDPAVLWGFIRRYAPRT
CCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
GPETHPGLDRLVKHALKYFSDFVRPAKTYRAPTPEERAALEDLAETLTEHAGSTDPEALQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AAVYEVGRRHFPDTSGKAKSPDGRPGVSQAWFTSLYNVLFGEARGPRFGSFVALYGVDET
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
RGLIAAALSGALVAEHAAFAAGKAAPVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA