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The map label for this gene is argE [H]

Identifier: 170747966

GI number: 170747966

Start: 1631228

End: 1632460

Strand: Reverse

Name: argE [H]

Synonym: Mrad2831_1548

Alternate gene names: 170747966

Gene position: 1632460-1631228 (Counterclockwise)

Preceding gene: 170747975

Following gene: 170747964

Centisome position: 26.86

GC content: 74.61

Gene sequence:

>1233_bases
ATGACAGAGCCCGCACAGACCGCCTCGCCGCGCCCCGGCACGCCCGATCCGGCGGCACTGCTCGCCGCGCTCGTCGCCTT
CGACACGGTGAGCGCCCGCTCGAACCTGCCGCTGATCGACTGGGCGGAGGCCTATTGCCGCGGCCACGGCGCCGCGGTCG
AGCGGGTGCCGGATCCGTCGGGCCGGAAGGCGGCGCTGCTGGTCAGCGTCGGACCGTTCGAGACCCGTCCCGGCTACGTG
CTCTCCGGCCACAGCGACGTGGTGCCGACCGACGGCCAGCCCTGGTCGTCGGACCCGTTCGCCCTGCGGGAGGAGGGCGG
GCGGCTCTACGGGCGCGGCACCTCCGACATGAAGGGGTTCCTCGCGGTCTGCCTCGCGCTCCTGCCCGAGATGGTGGCGG
CGGAGCTCGCCACCCCGATCCACCTCGCGATCTCGTACGACGAGGAGATCGGGTGCCTCGGCGTGCGCCCGCTGATCGCC
CGGATGCTCGAGCGCGTGCCGCGGCCGCTCGGCTGCTTCGTGGGCGAGCCGACCGGGATGGACGTGGTGGTCGGCCACAA
GGGCAAGGCGGCCGCCCGCCTCACCTTCCGCGGCAAGGCCAGCCACTCGGCCCTGGCGCCCCAGGGGGTCAACGCGGTCG
AGTACGCCGCCCGCTTCATCGAGCATGTCCGCCTGTCCGCGGAGGCCATCGCCCGGGACGGGGCCCGCGACCCGCTCTAC
GACGTGCCCCACACCACCGGCCTGTCGAGCGTGGTCCGGGGCGGATCGGCGCTCAACATCGTGCCCGACACCTGCAGCGT
CGAGTTCGAGTACCGGGCGATCGGCGCGGACGATGCCGCCGCGCTGGCGGCGTCCGCGATCGCCTACGCCACCGGGACGC
TGGCGCCGCTGATGCGGGCCGGCGATCCGGCCTGCGGCGTCGCGGTCGAGCCGCTGATCGACTATCCGGGCCTCGACACC
GATCCGGAGGCGGAGATCGTGACCCTGGCCAAGCGCCTCGCGGGCCGCAACGGCCACGCCAAGGTCTCGTACGGCACGGA
GGGCGGGCTGTTCGAGCGGCTCGGCGGCGTGCCGGCCGTGGTGATCGGGCCGGGCTCGATCGCGCGCGCCCACAGGGCGG
ACGAGTACGTCACCCGGGACGAACTCGAGGCCTGCGCGGGCTTCGTGCGGCGGCTGATCGGCGCCTGCGTGACCGGCCCC
GCGTCAGCGTCCCGAGGGGTGATCCCCGGCTGA

Upstream 100 bases:

>100_bases
AGACCGATTCGCGCGGGTCGGCACGCCGGCCGCGACCCGGCCAAGATCCGGCCAAGATCCGGTCACGACCTCGCCACGAC
CTCGCCACGCCATGGGATCC

Downstream 100 bases:

>100_bases
ACCGGCCTCCGCGTCGGTCGCGAGAGGCGCCGGTCCGCCGAGCGTCCGCCGCGCGGCGCGATCTCACCAGGGGATGCGGC
CGAAGCGGTCGACCAGCCGC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTEPAQTASPRPGTPDPAALLAALVAFDTVSARSNLPLIDWAEAYCRGHGAAVERVPDPSGRKAALLVSVGPFETRPGYV
LSGHSDVVPTDGQPWSSDPFALREEGGRLYGRGTSDMKGFLAVCLALLPEMVAAELATPIHLAISYDEEIGCLGVRPLIA
RMLERVPRPLGCFVGEPTGMDVVVGHKGKAAARLTFRGKASHSALAPQGVNAVEYAARFIEHVRLSAEAIARDGARDPLY
DVPHTTGLSSVVRGGSALNIVPDTCSVEFEYRAIGADDAAALAASAIAYATGTLAPLMRAGDPACGVAVEPLIDYPGLDT
DPEAEIVTLAKRLAGRNGHAKVSYGTEGGLFERLGGVPAVVIGPGSIARAHRADEYVTRDELEACAGFVRRLIGACVTGP
ASASRGVIPG

Sequences:

>Translated_410_residues
MTEPAQTASPRPGTPDPAALLAALVAFDTVSARSNLPLIDWAEAYCRGHGAAVERVPDPSGRKAALLVSVGPFETRPGYV
LSGHSDVVPTDGQPWSSDPFALREEGGRLYGRGTSDMKGFLAVCLALLPEMVAAELATPIHLAISYDEEIGCLGVRPLIA
RMLERVPRPLGCFVGEPTGMDVVVGHKGKAAARLTFRGKASHSALAPQGVNAVEYAARFIEHVRLSAEAIARDGARDPLY
DVPHTTGLSSVVRGGSALNIVPDTCSVEFEYRAIGADDAAALAASAIAYATGTLAPLMRAGDPACGVAVEPLIDYPGLDT
DPEAEIVTLAKRLAGRNGHAKVSYGTEGGLFERLGGVPAVVIGPGSIARAHRADEYVTRDELEACAGFVRRLIGACVTGP
ASASRGVIPG
>Mature_409_residues
TEPAQTASPRPGTPDPAALLAALVAFDTVSARSNLPLIDWAEAYCRGHGAAVERVPDPSGRKAALLVSVGPFETRPGYVL
SGHSDVVPTDGQPWSSDPFALREEGGRLYGRGTSDMKGFLAVCLALLPEMVAAELATPIHLAISYDEEIGCLGVRPLIAR
MLERVPRPLGCFVGEPTGMDVVVGHKGKAAARLTFRGKASHSALAPQGVNAVEYAARFIEHVRLSAEAIARDGARDPLYD
VPHTTGLSSVVRGGSALNIVPDTCSVEFEYRAIGADDAAALAASAIAYATGTLAPLMRAGDPACGVAVEPLIDYPGLDTD
PEAEIVTLAKRLAGRNGHAKVSYGTEGGLFERLGGVPAVVIGPGSIARAHRADEYVTRDELEACAGFVRRLIGACVTGPA
SASRGVIPG

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=381, Percent_Identity=29.6587926509186, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788816, Length=340, Percent_Identity=25.2941176470588, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42588; Mature: 42457

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPAQTASPRPGTPDPAALLAALVAFDTVSARSNLPLIDWAEAYCRGHGAAVERVPDPS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCC
GRKAALLVSVGPFETRPGYVLSGHSDVVPTDGQPWSSDPFALREEGGRLYGRGTSDMKGF
CCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCHHHHHH
LAVCLALLPEMVAAELATPIHLAISYDEEIGCLGVRPLIARMLERVPRPLGCFVGEPTGM
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCC
DVVVGHKGKAAARLTFRGKASHSALAPQGVNAVEYAARFIEHVRLSAEAIARDGARDPLY
EEEEECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DVPHTTGLSSVVRGGSALNIVPDTCSVEFEYRAIGADDAAALAASAIAYATGTLAPLMRA
CCCCCCCHHHHHCCCCEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GDPACGVAVEPLIDYPGLDTDPEAEIVTLAKRLAGRNGHAKVSYGTEGGLFERLGGVPAV
CCCCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCEE
VIGPGSIARAHRADEYVTRDELEACAGFVRRLIGACVTGPASASRGVIPG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPAQTASPRPGTPDPAALLAALVAFDTVSARSNLPLIDWAEAYCRGHGAAVERVPDPS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCC
GRKAALLVSVGPFETRPGYVLSGHSDVVPTDGQPWSSDPFALREEGGRLYGRGTSDMKGF
CCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCHHHHHH
LAVCLALLPEMVAAELATPIHLAISYDEEIGCLGVRPLIARMLERVPRPLGCFVGEPTGM
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCC
DVVVGHKGKAAARLTFRGKASHSALAPQGVNAVEYAARFIEHVRLSAEAIARDGARDPLY
EEEEECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DVPHTTGLSSVVRGGSALNIVPDTCSVEFEYRAIGADDAAALAASAIAYATGTLAPLMRA
CCCCCCCHHHHHCCCCEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GDPACGVAVEPLIDYPGLDTDPEAEIVTLAKRLAGRNGHAKVSYGTEGGLFERLGGVPAV
CCCCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCEE
VIGPGSIARAHRADEYVTRDELEACAGFVRRLIGACVTGPASASRGVIPG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]