Click here to switch to the map view.

The map label for this gene is thrC [H]

Identifier: 170747959

GI number: 170747959

Start: 1624843

End: 1625982

Strand: Reverse

Name: thrC [H]

Synonym: Mrad2831_1541

Alternate gene names: 170747959

Gene position: 1625982-1624843 (Counterclockwise)

Preceding gene: 170747960

Following gene: 170747958

Centisome position: 26.75

GC content: 74.65

Gene sequence:

>1140_bases
ATGCCTCCGTCCGCCGCCTATCTCGACCCCGCCACCGGGGCGACCTACCCGATCGAGACGCCGCGCTGGCGCTCGGAGAC
GGGCGGTCCGCTGATGATCACCGACCTGCCGGGGATCGGGCGCGGCGAGATCGACACGGGCCAGCGCTCCCTCTGGCGCT
ACGCCGCCGCCCTGCCGGTGGCGGTGGCCGACCCGGTCACGCTGGGGGAGGGCTGCACGCCGCTGGTGCGCCGGCCCTGG
CGGGGCGGGCACGCGCATTTCAAGCTCGAATGGTTCGCGCCCTCGGGCAGCTTCAAGGACCGGGGCGCCTCCGTGATGCT
GTCGATCCTGCGCCAGCAGGGGATCGACGCGGTGCTGGAGGATTCCTCCGGCAATGGCGGGGCCGCGGTGGCGACCTACG
CGGCGGCGGCCGGGATGCGGGCCAAGATCCTGGTCCCGGCCTCGACCTCGCCGGCCAAGACCGTGCAGATGCGCGCCGTC
GGCGCGGAGGTCGAGCTGATCCCCGGCACCCGCCAGGACACCGCCGACGCGGCCGTCGCCCAGGCGGACTCGATCTTCTA
CGCCAGCCACAACTGGCAGGCCCACTTCCTCCAGGGCACCAAGACGCTGGCCTACGAGCTGTGGGAGGATCTGGGTTTCG
CCGCGCCCGACCATGTCATCATCCCCTGCGGCGCGGGCAGCAACATCCTCGGCTGCGACATCGGCTTCTCGGAGCTGCTG
CGCCGGGGCGCGATCGCCCGTCTGCCGCGGCTCTACGCGGTCCAGCCGGCCCACTGCGCGCCCCTGCACGCGGGCTTCGA
GGCCGGCGCGGCGGATTTCGTGCCGGTCACCCCGCGCCCGACGCTGGCCGAGGGCGCCTCGATCGCCCAGCCGGTCCGCG
GCCGGGCGGTGCTGGCGGCGCTCCGCCGCTCCGGCGGCGGCACCGTGGCGGTCTCCGAGGCAGCCATCGAGGCGGCGCTG
ATGGAGCTCGCCCGCTCGGGCCTCTACGTCGAGCCGACCTGCGCCATGGCGGCGGCGGCGCTCACCGATCTCACCGCGCG
CGGCGCGATCCGGCCCGAGGACACCACCGTGGTGGTGCTCACCGGCACCGGCATCAAGGCGACGCCGCGCATCGCCGAGC
TTCTGGGCCTCGCCCCGTAA

Upstream 100 bases:

>100_bases
CGCGCAGCACGGCGCGCTGTCCCATCCCCGAACTGGGGGGCGCGCCGTCGCAGATTATTTTGTATTCTCTTTTCCGAACC
ACCCCGGAAACCGAGCCGCG

Downstream 100 bases:

>100_bases
CCGGGCCCCGCCACGAGATCCGCACGCGATCAGGAGGACACACCATGCGCAACAACATCCCCGCCACCGTCGGGATGCCG
GTCGAGGAGGTGGACACCCC

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MPPSAAYLDPATGATYPIETPRWRSETGGPLMITDLPGIGRGEIDTGQRSLWRYAAALPVAVADPVTLGEGCTPLVRRPW
RGGHAHFKLEWFAPSGSFKDRGASVMLSILRQQGIDAVLEDSSGNGGAAVATYAAAAGMRAKILVPASTSPAKTVQMRAV
GAEVELIPGTRQDTADAAVAQADSIFYASHNWQAHFLQGTKTLAYELWEDLGFAAPDHVIIPCGAGSNILGCDIGFSELL
RRGAIARLPRLYAVQPAHCAPLHAGFEAGAADFVPVTPRPTLAEGASIAQPVRGRAVLAALRRSGGGTVAVSEAAIEAAL
MELARSGLYVEPTCAMAAAALTDLTARGAIRPEDTTVVVLTGTGIKATPRIAELLGLAP

Sequences:

>Translated_379_residues
MPPSAAYLDPATGATYPIETPRWRSETGGPLMITDLPGIGRGEIDTGQRSLWRYAAALPVAVADPVTLGEGCTPLVRRPW
RGGHAHFKLEWFAPSGSFKDRGASVMLSILRQQGIDAVLEDSSGNGGAAVATYAAAAGMRAKILVPASTSPAKTVQMRAV
GAEVELIPGTRQDTADAAVAQADSIFYASHNWQAHFLQGTKTLAYELWEDLGFAAPDHVIIPCGAGSNILGCDIGFSELL
RRGAIARLPRLYAVQPAHCAPLHAGFEAGAADFVPVTPRPTLAEGASIAQPVRGRAVLAALRRSGGGTVAVSEAAIEAAL
MELARSGLYVEPTCAMAAAALTDLTARGAIRPEDTTVVVLTGTGIKATPRIAELLGLAP
>Mature_378_residues
PPSAAYLDPATGATYPIETPRWRSETGGPLMITDLPGIGRGEIDTGQRSLWRYAAALPVAVADPVTLGEGCTPLVRRPWR
GGHAHFKLEWFAPSGSFKDRGASVMLSILRQQGIDAVLEDSSGNGGAAVATYAAAAGMRAKILVPASTSPAKTVQMRAVG
AEVELIPGTRQDTADAAVAQADSIFYASHNWQAHFLQGTKTLAYELWEDLGFAAPDHVIIPCGAGSNILGCDIGFSELLR
RGAIARLPRLYAVQPAHCAPLHAGFEAGAADFVPVTPRPTLAEGASIAQPVRGRAVLAALRRSGGGTVAVSEAAIEAALM
ELARSGLYVEPTCAMAAAALTDLTARGAIRPEDTTVVVLTGTGIKATPRIAELLGLAP

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=179, Percent_Identity=31.8435754189944, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 39387; Mature: 39256

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSAAYLDPATGATYPIETPRWRSETGGPLMITDLPGIGRGEIDTGQRSLWRYAAALPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCE
AVADPVTLGEGCTPLVRRPWRGGHAHFKLEWFAPSGSFKDRGASVMLSILRQQGIDAVLE
EECCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEE
DSSGNGGAAVATYAAAAGMRAKILVPASTSPAKTVQMRAVGAEVELIPGTRQDTADAAVA
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEECCEEEECCCCCCCHHHHHHH
QADSIFYASHNWQAHFLQGTKTLAYELWEDLGFAAPDHVIIPCGAGSNILGCDIGFSELL
HHCEEEEECCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEECCCHHHHH
RRGAIARLPRLYAVQPAHCAPLHAGFEAGAADFVPVTPRPTLAEGASIAQPVRGRAVLAA
HCCHHHHCCHHEEECCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCHHHCCCCHHHHHHH
LRRSGGGTVAVSEAAIEAALMELARSGLYVEPTCAMAAAALTDLTARGAIRPEDTTVVVL
HHHCCCCEEEEHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEE
TGTGIKATPRIAELLGLAP
ECCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
PPSAAYLDPATGATYPIETPRWRSETGGPLMITDLPGIGRGEIDTGQRSLWRYAAALPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCE
AVADPVTLGEGCTPLVRRPWRGGHAHFKLEWFAPSGSFKDRGASVMLSILRQQGIDAVLE
EECCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEE
DSSGNGGAAVATYAAAAGMRAKILVPASTSPAKTVQMRAVGAEVELIPGTRQDTADAAVA
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEECCEEEECCCCCCCHHHHHHH
QADSIFYASHNWQAHFLQGTKTLAYELWEDLGFAAPDHVIIPCGAGSNILGCDIGFSELL
HHCEEEEECCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEECCCHHHHH
RRGAIARLPRLYAVQPAHCAPLHAGFEAGAADFVPVTPRPTLAEGASIAQPVRGRAVLAA
HCCHHHHCCHHEEECCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCHHHCCCCHHHHHHH
LRRSGGGTVAVSEAAIEAALMELARSGLYVEPTCAMAAAALTDLTARGAIRPEDTTVVVL
HHHCCCCEEEEHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEE
TGTGIKATPRIAELLGLAP
ECCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]