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The map label for this gene is feaR [H]

Identifier: 170747930

GI number: 170747930

Start: 1583260

End: 1584234

Strand: Reverse

Name: feaR [H]

Synonym: Mrad2831_1512

Alternate gene names: 170747930

Gene position: 1584234-1583260 (Counterclockwise)

Preceding gene: 170747931

Following gene: 170747921

Centisome position: 26.07

GC content: 73.33

Gene sequence:

>975_bases
ATGCGCCGGGTCTTCTCGACGGCCGGGATCCATCCCCGGACGCGCTTCAAGCTCTGGCAGGAGGTCGTCGCCGACCGGAT
CGGGCCGGTCGAGCAGCGCCGCCGCGCCGACGGGCCGTTCGCGGGCGAGATCGAGATCGGCGCCGTCGGTCCGCTGACAT
TCAGCCGGATCACCCAGGGCGCCATCACGACCACGATCACCGCCGACACGGTCCGGCGCCGGCCGGACGGGCTCATCCGC
GTGAATTTCCGCCTCGCCGGGTCGTCGACCTTCCAGCAGCACGGTCGCGAGGCGCTGCAGGGCGCCGGAGACTTCACCGT
CGTCGACCATCACCCGGGCGTGCTGGACGCGCGCACGGATGGCCAGACCCTGGTCATGGCCCTGCCGCGGGAGCGCCTCG
AGGGCGTGCTCGGGCCGGCTCGGCTGTTCGCGGCCCTGACGATGACCGCCGAATCGGCGACGACCCGGCTGGTGACGACC
TTCTTCGGGGATCTGCTCCGGGTGAACCGGCGGCTCTCTCCCGAGACGGCCGAGCGCATGGCGGCCATCGGCGTCGATCT
GATCGTGGCCGCCCTCGCCGAGCGGATGGCCCGGGAGGTGCCGCGTACCCTGCACGGCAGCGTCGTCGTCCAGCGCGCCA
AGGCCCATGTCGAGGCGAATCTCGGCGATCCGTCCCTCGATCCGCCCCGGCTCGCCGCCGCGATGGGCGTGTCCCTGCGC
CGGCTCCAGGAGCTGTTCCACGAGCGCGGCCAGCACATCTCTGACTGGATCTGGGAGCGCCGCCTCGCGGCCGCGGCCAG
GCGCCTCTCCGATCCGGTCAGCCTGCACCGCCCGATCGGCGTCGTGGCCTACGAGTGCGGCTTCGCGAGCCAGGCCCATT
TCGCGCGGCGCTTCAAGGACCGCCACGGCCTGTCGCCCCGCGCCTACCGGGAGGCCGCCGCCCTGCGCCTGTCCGGCAGC
CGGCCGGATCCGTGA

Upstream 100 bases:

>100_bases
AATCCAATACCGGTCCTCGGATCGCCCTTCAGGGCGGCCGGTTCCGTCCGGCGGACAGGCCCTCCGCGAGCCGCGCGGCA
GCCGCTCCCCGAGTCCCTTG

Downstream 100 bases:

>100_bases
GGCGCCGCGATGTCGGTGCCCGTCGCGGGCGGCCGGGGCGCGGCGGCGGGACGAGGGGCGCCCCGGGGGCGGCCCTCGGG
GCCGCGGCCCCCCGCCGCCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRRVFSTAGIHPRTRFKLWQEVVADRIGPVEQRRRADGPFAGEIEIGAVGPLTFSRITQGAITTTITADTVRRRPDGLIR
VNFRLAGSSTFQQHGREALQGAGDFTVVDHHPGVLDARTDGQTLVMALPRERLEGVLGPARLFAALTMTAESATTRLVTT
FFGDLLRVNRRLSPETAERMAAIGVDLIVAALAERMAREVPRTLHGSVVVQRAKAHVEANLGDPSLDPPRLAAAMGVSLR
RLQELFHERGQHISDWIWERRLAAAARRLSDPVSLHRPIGVVAYECGFASQAHFARRFKDRHGLSPRAYREAAALRLSGS
RPDP

Sequences:

>Translated_324_residues
MRRVFSTAGIHPRTRFKLWQEVVADRIGPVEQRRRADGPFAGEIEIGAVGPLTFSRITQGAITTTITADTVRRRPDGLIR
VNFRLAGSSTFQQHGREALQGAGDFTVVDHHPGVLDARTDGQTLVMALPRERLEGVLGPARLFAALTMTAESATTRLVTT
FFGDLLRVNRRLSPETAERMAAIGVDLIVAALAERMAREVPRTLHGSVVVQRAKAHVEANLGDPSLDPPRLAAAMGVSLR
RLQELFHERGQHISDWIWERRLAAAARRLSDPVSLHRPIGVVAYECGFASQAHFARRFKDRHGLSPRAYREAAALRLSGS
RPDP
>Mature_324_residues
MRRVFSTAGIHPRTRFKLWQEVVADRIGPVEQRRRADGPFAGEIEIGAVGPLTFSRITQGAITTTITADTVRRRPDGLIR
VNFRLAGSSTFQQHGREALQGAGDFTVVDHHPGVLDARTDGQTLVMALPRERLEGVLGPARLFAALTMTAESATTRLVTT
FFGDLLRVNRRLSPETAERMAAIGVDLIVAALAERMAREVPRTLHGSVVVQRAKAHVEANLGDPSLDPPRLAAAMGVSLR
RLQELFHERGQHISDWIWERRLAAAARRLSDPVSLHRPIGVVAYECGFASQAHFARRFKDRHGLSPRAYREAAALRLSGS
RPDP

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=272, Percent_Identity=24.2647058823529, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35727; Mature: 35727

Theoretical pI: Translated: 11.73; Mature: 11.73

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVFSTAGIHPRTRFKLWQEVVADRIGPVEQRRRADGPFAGEIEIGAVGPLTFSRITQG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHCC
AITTTITADTVRRRPDGLIRVNFRLAGSSTFQQHGREALQGAGDFTVVDHHPGVLDARTD
CCEEEEEHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEECCCC
GQTLVMALPRERLEGVLGPARLFAALTMTAESATTRLVTTFFGDLLRVNRRLSPETAERM
CCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AAIGVDLIVAALAERMAREVPRTLHGSVVVQRAKAHVEANLGDPSLDPPRLAAAMGVSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
RLQELFHERGQHISDWIWERRLAAAARRLSDPVSLHRPIGVVAYECGFASQAHFARRFKD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHHH
RHGLSPRAYREAAALRLSGSRPDP
HCCCCHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MRRVFSTAGIHPRTRFKLWQEVVADRIGPVEQRRRADGPFAGEIEIGAVGPLTFSRITQG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHCC
AITTTITADTVRRRPDGLIRVNFRLAGSSTFQQHGREALQGAGDFTVVDHHPGVLDARTD
CCEEEEEHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEECCCC
GQTLVMALPRERLEGVLGPARLFAALTMTAESATTRLVTTFFGDLLRVNRRLSPETAERM
CCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AAIGVDLIVAALAERMAREVPRTLHGSVVVQRAKAHVEANLGDPSLDPPRLAAAMGVSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
RLQELFHERGQHISDWIWERRLAAAARRLSDPVSLHRPIGVVAYECGFASQAHFARRFKD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHHH
RHGLSPRAYREAAALRLSGSRPDP
HCCCCHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]