| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is livF [H]
Identifier: 170747852
GI number: 170747852
Start: 1499437
End: 1500234
Strand: Reverse
Name: livF [H]
Synonym: Mrad2831_1434
Alternate gene names: 170747852
Gene position: 1500234-1499437 (Counterclockwise)
Preceding gene: 170747853
Following gene: 170747848
Centisome position: 24.68
GC content: 77.19
Gene sequence:
>798_bases ATGAGCGCCGCGCCGACCCTCCTGGAGGTCGAGGCCCTGGAGGTCGTCTACGGCGGGGCGGTGCACGCCCTGCACGGCGT CGACCTCGCGGTCCGGGCGGGGGAGATCGTCGCCCTGGTCGGCGCCAACGGCGCCGGCAAGACGACCCTTCTGCGGGCGG TGTCGAACCTGCTGCCGGCCCTGCGCGGCCGGGTCACGGCCGGGCGCCTCGCCTATGACGGGCGCGACGCGACGCGGACC CGGACCGACGCCCTCGTCCGCGCCGGTCTCGTGGGCGTGCTGGAGGGGCGCCACTGCTTCCGGGGCCTGAGCGTCCAGGA GAACCTCGTCGCGGGCGGCCTCGGGCGCGGCTCGGGCCGCGGCGGCCTGCGCGCCGATCTGGAGCGGGTCTACGGCCTGT TCCCGCGGCTCGCCGCGAAGCGGGGCGTCGCCGCCGGCCTGCTCTCGGGCGGCGAGCAGCAGATGGCGGCGATCGGTCGG GCGCTGATGGGGCGGCCGCGGCTGCTCGTCCTCGACGAGCCGTCCATGGGACTCGCCCCCCGCGTGGTGGAGGAGATCTA CCGGGTGCTCGCCGGCCTGAACCGCGCCGAGGGTCTGACCCTGCTGGTGGCCGAGCAGAATCTCCGCCTCGCCCTGCGCC ACGCCCACCACGCCGTCGTGCTGGAGAACGGCCGCAGCGCGCTCGCCGGCACCGCCGTGTCCCTGCGAGGGCGGGACGAC GTCCGGTCCCTGTATCTCGGCGGCGCCGATGAGCCCGACGCGGCGCTGCCGGAGACGCGCCGCCGCGCGCCCGCCTGA
Upstream 100 bases:
>100_bases GCACGGCATCACCCCGCGCGACTGCGCGGCGGAGGAGGCCGCGGACGCGGGCGGCAAGCACGCCGCCGCGGCGGCCCGGT GAGCGCCCGGTGAGCGCCCG
Downstream 100 bases:
>100_bases CGGCGCCGGCCTGCGTCAGGACTCCCGGTCGGCGCGGCGCAGGGACCAGAGCAGGGTGCCGTGGGCGTCGACCAGCCACA GGGCGTTCACCGCGTCGTCC
Product: ABC transporter-like protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 265; Mature: 264
Protein sequence:
>265_residues MSAAPTLLEVEALEVVYGGAVHALHGVDLAVRAGEIVALVGANGAGKTTLLRAVSNLLPALRGRVTAGRLAYDGRDATRT RTDALVRAGLVGVLEGRHCFRGLSVQENLVAGGLGRGSGRGGLRADLERVYGLFPRLAAKRGVAAGLLSGGEQQMAAIGR ALMGRPRLLVLDEPSMGLAPRVVEEIYRVLAGLNRAEGLTLLVAEQNLRLALRHAHHAVVLENGRSALAGTAVSLRGRDD VRSLYLGGADEPDAALPETRRRAPA
Sequences:
>Translated_265_residues MSAAPTLLEVEALEVVYGGAVHALHGVDLAVRAGEIVALVGANGAGKTTLLRAVSNLLPALRGRVTAGRLAYDGRDATRT RTDALVRAGLVGVLEGRHCFRGLSVQENLVAGGLGRGSGRGGLRADLERVYGLFPRLAAKRGVAAGLLSGGEQQMAAIGR ALMGRPRLLVLDEPSMGLAPRVVEEIYRVLAGLNRAEGLTLLVAEQNLRLALRHAHHAVVLENGRSALAGTAVSLRGRDD VRSLYLGGADEPDAALPETRRRAPA >Mature_264_residues SAAPTLLEVEALEVVYGGAVHALHGVDLAVRAGEIVALVGANGAGKTTLLRAVSNLLPALRGRVTAGRLAYDGRDATRTR TDALVRAGLVGVLEGRHCFRGLSVQENLVAGGLGRGSGRGGLRADLERVYGLFPRLAAKRGVAAGLLSGGEQQMAAIGRA LMGRPRLLVLDEPSMGLAPRVVEEIYRVLAGLNRAEGLTLLVAEQNLRLALRHAHHAVVLENGRSALAGTAVSLRGRDDV RSLYLGGADEPDAALPETRRRAPA
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI156105685, Length=219, Percent_Identity=35.1598173515982, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI153792144, Length=218, Percent_Identity=28.4403669724771, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI42741659, Length=221, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI255708477, Length=230, Percent_Identity=30, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI148612844, Length=230, Percent_Identity=30, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4505771, Length=221, Percent_Identity=30.316742081448, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI9961250, Length=223, Percent_Identity=30.4932735426009, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI9961252, Length=221, Percent_Identity=30.316742081448, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI105990541, Length=214, Percent_Identity=28.5046728971963, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI27477115, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI45446740, Length=234, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI47078218, Length=234, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI27436953, Length=222, Percent_Identity=27.4774774774775, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI21536376, Length=243, Percent_Identity=25.5144032921811, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI150417984, Length=230, Percent_Identity=30, Blast_Score=69, Evalue=6e-12, Organism=Escherichia coli, GI87082268, Length=230, Percent_Identity=46.0869565217391, Blast_Score=189, Evalue=1e-49, Organism=Escherichia coli, GI1787029, Length=222, Percent_Identity=31.5315315315315, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1788225, Length=234, Percent_Identity=32.4786324786325, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1790544, Length=253, Percent_Identity=30.0395256916996, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=28.4046692607004, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1789672, Length=210, Percent_Identity=28.0952380952381, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786319, Length=253, Percent_Identity=30.8300395256917, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1790190, Length=211, Percent_Identity=33.175355450237, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787089, Length=227, Percent_Identity=32.5991189427313, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789873, Length=225, Percent_Identity=30.6666666666667, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1786703, Length=219, Percent_Identity=35.6164383561644, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1790162, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1789593, Length=223, Percent_Identity=33.1838565022422, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1789963, Length=238, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787792, Length=230, Percent_Identity=28.2608695652174, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1790525, Length=235, Percent_Identity=28.5106382978723, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1788210, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1786872, Length=192, Percent_Identity=30.2083333333333, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI48995001, Length=226, Percent_Identity=30.5309734513274, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787370, Length=231, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87081834, Length=216, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787548, Length=240, Percent_Identity=30, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1788897, Length=257, Percent_Identity=30.7392996108949, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1787712, Length=243, Percent_Identity=26.7489711934156, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1788506, Length=244, Percent_Identity=29.9180327868852, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1788761, Length=212, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI87081791, Length=225, Percent_Identity=27.5555555555556, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1786253, Length=207, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=9e-14, Organism=Escherichia coli, GI1789991, Length=181, Percent_Identity=30.3867403314917, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI87082267, Length=235, Percent_Identity=28.0851063829787, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787105, Length=196, Percent_Identity=31.1224489795918, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1786563, Length=222, Percent_Identity=30.1801801801802, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI87081782, Length=193, Percent_Identity=30.5699481865285, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1788644, Length=236, Percent_Identity=28.3898305084746, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=24.8847926267281, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI48994943, Length=251, Percent_Identity=29.8804780876494, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1788472, Length=230, Percent_Identity=24.7826086956522, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1788450, Length=230, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787112, Length=224, Percent_Identity=31.6964285714286, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1790467, Length=218, Percent_Identity=27.9816513761468, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1789586, Length=242, Percent_Identity=30.1652892561983, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1786345, Length=232, Percent_Identity=28.448275862069, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1787164, Length=207, Percent_Identity=30.9178743961353, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI86563255, Length=209, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI193211015, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71996809, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17510237, Length=233, Percent_Identity=27.4678111587983, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193211017, Length=253, Percent_Identity=26.4822134387352, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193208177, Length=220, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI115533608, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193202349, Length=226, Percent_Identity=25.2212389380531, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI115533592, Length=229, Percent_Identity=27.0742358078603, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI24641565, Length=230, Percent_Identity=31.304347826087, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24659289, Length=222, Percent_Identity=30.6306306306306, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24666092, Length=226, Percent_Identity=26.9911504424779, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21357907, Length=222, Percent_Identity=30.1801801801802, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24650853, Length=207, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24650855, Length=200, Percent_Identity=29.5, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI281362751, Length=208, Percent_Identity=28.8461538461538, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24653245, Length=236, Percent_Identity=31.3559322033898, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI281363262, Length=236, Percent_Identity=31.3559322033898, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 27667; Mature: 27536
Theoretical pI: Translated: 10.85; Mature: 10.85
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSAAPTLLEVEALEVVYGGAVHALHGVDLAVRAGEIVALVGANGAGKTTLLRAVSNLLPA CCCCCCEEEHHHHHHHHCCHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH LRGRVTAGRLAYDGRDATRTRTDALVRAGLVGVLEGRHCFRGLSVQENLVAGGLGRGSGR HHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHCCCCCCCCC GGLRADLERVYGLFPRLAAKRGVAAGLLSGGEQQMAAIGRALMGRPRLLVLDEPSMGLAP CCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCH RVVEEIYRVLAGLNRAEGLTLLVAEQNLRLALRHAHHAVVLENGRSALAGTAVSLRGRDD HHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCEEEEEECCCCCHHCCEEEECCCHH VRSLYLGGADEPDAALPETRRRAPA HHHHEECCCCCCCCCCCHHHHCCCC >Mature Secondary Structure SAAPTLLEVEALEVVYGGAVHALHGVDLAVRAGEIVALVGANGAGKTTLLRAVSNLLPA CCCCCEEEHHHHHHHHCCHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH LRGRVTAGRLAYDGRDATRTRTDALVRAGLVGVLEGRHCFRGLSVQENLVAGGLGRGSGR HHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHCCCCCCCCC GGLRADLERVYGLFPRLAAKRGVAAGLLSGGEQQMAAIGRALMGRPRLLVLDEPSMGLAP CCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCH RVVEEIYRVLAGLNRAEGLTLLVAEQNLRLALRHAHHAVVLENGRSALAGTAVSLRGRDD HHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCEEEEEECCCCCHHCCEEEECCCHH VRSLYLGGADEPDAALPETRRRAPA HHHHEECCCCCCCCCCCHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]