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The map label for this gene is sufS [C]

Identifier: 170747845

GI number: 170747845

Start: 1492004

End: 1493998

Strand: Reverse

Name: sufS [C]

Synonym: Mrad2831_1427

Alternate gene names: 170747845

Gene position: 1493998-1492004 (Counterclockwise)

Preceding gene: 170747846

Following gene: 170747843

Centisome position: 24.58

GC content: 75.24

Gene sequence:

>1995_bases
ATGACTACGCCTGAGGCCTTCGCCCTCGGGCTGCCCGGGGCGAGCCCGGGCGAGCTGGCCCACGCGGATCTCGTCGGGCG
CCTCGCCCGGGAGATCTACCGGCAGGGGCAGGCCGCGAGCCAGCCGTTCGCGCCGGCGATCCCCGCCGGCCCCCAGGTCC
CGCAGGCGCTCGAGGGCCTGCCCCAGGGCCCGGGCGGGGCGCCGCTGCCGGGCGCGCCCGTGGGCGTCCCCTCCGCTCCC
GCGGGCGGCCAGCCCGCCGGGCTGCAGCCCGACGCGTCGGCGCTGCCGGCGCGCTCCTTCGGGGCGCCGCCGGTCGGCCT
GCCGGGCCTCTCCGGCCCGACCCTGCCGAACCGCGCACCCGCGAGCCCGGCGTTCCCCGACGCGGCGGCGATCCCGCCTG
TCCACCCCGCGAGCCCGCGCCCCGTCCTGCCGGACTTCTCCCTCGCCGGCGCCCCGGCGCTGGCGGCCGCCCTCCCCGGC
GGTCCGGAGCTGCACCGCCAGATCGCCGCCGACCACCCCCGCGCCAACGCCTTCGCGCACGCCCTCGTCCCGGACCTCGT
GCCCGCCGACCCGTCGAAGGCCGGCCGCGATGAGGCGCCGGAGAGCCTCGCCCGGACCGGTCGGCGGTCCCGGGCGCCCG
AAGCGCCGGCTGGCGACTACTACTTCCTGCCTCTCGGCCCCGGGCCGGCCCGCGGGGCGGCGGCGAGCCCACGGGTCGAG
CCGACCCGCTATCCCGGTCCGGCGCCGCGCCTCGCCGCCCAGGGATCGAGCCCGGTGGCGGCGCCCTTCGACGTGGAGCA
GGTCCGCCGGGACTTCCCGGCCCTGCACCAGAGCGTCAACGGCCACCCGCTGGTCTGGCTCGACAACGCCGCCACCACCC
ACAAGCCCCAGGCCGTGATCGACGCGACCGCGGCGTTCTACGCCCGGCACAACTCGAACATCCACCGGGCCGCCCACACC
CTGGCCGCGCGCGCCACGGACCTGTTCGAGGGCGGCCGCGAGGCGGTGCGCCGCTTCCTCAACGCCCCGTCGAAGGACGA
CATCGTCTTCCTGCGCGGCACCACGGAGGCGATCAACCTCGTCGCCAATTCCTACGGCCGGGCCCAGATCGGCCCGGGCG
ACGAGATCATCGTCTCGACCATCGAGCACCACGCCAACATCGTGCCCTGGCAGCTGCTGGCGCAGCAGACCGGGGCGACG
CTCCGGGTGATCCCGGTGAACGACCGCGGCGAGATCATCTTCGAGCAGTACGCGGCGCTCCTGTCGGGCCGCACCAAGAT
CGTCTCGGTGACGCAGGTGGCCAACGCGCTCGGCACCGTGAACCCGGTGCGGGAGATCATCCAGCTCGCCCACGCCTACG
GGGTGCCGGTGCTGGTCGACGCGGCGCAATCCTCGCCGCACATGCCGCTGGACGTGCAGTCCCTGGACGCGGACTTCCTG
GTCTTCTCCGGCCACAAGGTGTTCGGGCCGACGGGCATCGGCGCGCTCTACGGCAAGACGCACCTGCTCGAGGCGATGCC
GCCCTGGCAGGGCGGCGGCCACATGATCGAGGACGTCACCTTCGCGAAGACCGTCTACAAGGGCGCGCCCGAGAAGTTCG
AGGCCGGCACGCCCGACATCGCCGGGGCGGTCGGTCTGGGGGCGGCGCTCGACTACCTCGCGGGCATCGGCATGCCGGCG
ATCGCCGCCTACGAGCACGACCTCCTGGACTACGCGCAGGGCGGCCTCGCCGACGTGAAGGGCCTGCGCCTGATCGGCAC
GGCCCGGGAGAAGGCGAGCGTGATGTCCTTCGTGATCGAGGGGCAGACGAACGAGGCGGTGGCGCACCACCTCGACGCGC
ACGGCATCGCGGTGCGCTCGGGCCATCACTGCGCCCTGCCGGCCCTGCGCCGGTTCGGCGTCGACCAGTCGGTGCGGGCC
TCGCTCGCCTTCTACAACACCCGCGCGGATGTCGACGCCTTCCTGAGGGCGCTGCACACCCTGCCGCGGCCTTGA

Upstream 100 bases:

>100_bases
CACTCGATCGCCTCGCACCTCGTGACCCGCTACTTCTCGGCCGCCGTGCTGGTCGAGGACGCGATCGCCCGCCTCGATAA
CGTGCTGCTGGGCAACTACC

Downstream 100 bases:

>100_bases
GCAGAGGGCGCCGGCCGCGCGCCGGCGCCCCGTTGCGGGCCGGGCTCTCTACCCCGCCTTCGGCCGCAGGTGCCGGGTCC
TCACGGTGCCGTCGATGGCC

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MTTPEAFALGLPGASPGELAHADLVGRLAREIYRQGQAASQPFAPAIPAGPQVPQALEGLPQGPGGAPLPGAPVGVPSAP
AGGQPAGLQPDASALPARSFGAPPVGLPGLSGPTLPNRAPASPAFPDAAAIPPVHPASPRPVLPDFSLAGAPALAAALPG
GPELHRQIAADHPRANAFAHALVPDLVPADPSKAGRDEAPESLARTGRRSRAPEAPAGDYYFLPLGPGPARGAAASPRVE
PTRYPGPAPRLAAQGSSPVAAPFDVEQVRRDFPALHQSVNGHPLVWLDNAATTHKPQAVIDATAAFYARHNSNIHRAAHT
LAARATDLFEGGREAVRRFLNAPSKDDIVFLRGTTEAINLVANSYGRAQIGPGDEIIVSTIEHHANIVPWQLLAQQTGAT
LRVIPVNDRGEIIFEQYAALLSGRTKIVSVTQVANALGTVNPVREIIQLAHAYGVPVLVDAAQSSPHMPLDVQSLDADFL
VFSGHKVFGPTGIGALYGKTHLLEAMPPWQGGGHMIEDVTFAKTVYKGAPEKFEAGTPDIAGAVGLGAALDYLAGIGMPA
IAAYEHDLLDYAQGGLADVKGLRLIGTAREKASVMSFVIEGQTNEAVAHHLDAHGIAVRSGHHCALPALRRFGVDQSVRA
SLAFYNTRADVDAFLRALHTLPRP

Sequences:

>Translated_664_residues
MTTPEAFALGLPGASPGELAHADLVGRLAREIYRQGQAASQPFAPAIPAGPQVPQALEGLPQGPGGAPLPGAPVGVPSAP
AGGQPAGLQPDASALPARSFGAPPVGLPGLSGPTLPNRAPASPAFPDAAAIPPVHPASPRPVLPDFSLAGAPALAAALPG
GPELHRQIAADHPRANAFAHALVPDLVPADPSKAGRDEAPESLARTGRRSRAPEAPAGDYYFLPLGPGPARGAAASPRVE
PTRYPGPAPRLAAQGSSPVAAPFDVEQVRRDFPALHQSVNGHPLVWLDNAATTHKPQAVIDATAAFYARHNSNIHRAAHT
LAARATDLFEGGREAVRRFLNAPSKDDIVFLRGTTEAINLVANSYGRAQIGPGDEIIVSTIEHHANIVPWQLLAQQTGAT
LRVIPVNDRGEIIFEQYAALLSGRTKIVSVTQVANALGTVNPVREIIQLAHAYGVPVLVDAAQSSPHMPLDVQSLDADFL
VFSGHKVFGPTGIGALYGKTHLLEAMPPWQGGGHMIEDVTFAKTVYKGAPEKFEAGTPDIAGAVGLGAALDYLAGIGMPA
IAAYEHDLLDYAQGGLADVKGLRLIGTAREKASVMSFVIEGQTNEAVAHHLDAHGIAVRSGHHCALPALRRFGVDQSVRA
SLAFYNTRADVDAFLRALHTLPRP
>Mature_663_residues
TTPEAFALGLPGASPGELAHADLVGRLAREIYRQGQAASQPFAPAIPAGPQVPQALEGLPQGPGGAPLPGAPVGVPSAPA
GGQPAGLQPDASALPARSFGAPPVGLPGLSGPTLPNRAPASPAFPDAAAIPPVHPASPRPVLPDFSLAGAPALAAALPGG
PELHRQIAADHPRANAFAHALVPDLVPADPSKAGRDEAPESLARTGRRSRAPEAPAGDYYFLPLGPGPARGAAASPRVEP
TRYPGPAPRLAAQGSSPVAAPFDVEQVRRDFPALHQSVNGHPLVWLDNAATTHKPQAVIDATAAFYARHNSNIHRAAHTL
AARATDLFEGGREAVRRFLNAPSKDDIVFLRGTTEAINLVANSYGRAQIGPGDEIIVSTIEHHANIVPWQLLAQQTGATL
RVIPVNDRGEIIFEQYAALLSGRTKIVSVTQVANALGTVNPVREIIQLAHAYGVPVLVDAAQSSPHMPLDVQSLDADFLV
FSGHKVFGPTGIGALYGKTHLLEAMPPWQGGGHMIEDVTFAKTVYKGAPEKFEAGTPDIAGAVGLGAALDYLAGIGMPAI
AAYEHDLLDYAQGGLADVKGLRLIGTAREKASVMSFVIEGQTNEAVAHHLDAHGIAVRSGHHCALPALRRFGVDQSVRAS
LAFYNTRADVDAFLRALHTLPRP

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=267, Percent_Identity=27.3408239700375, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI156713448, Length=424, Percent_Identity=26.8867924528302, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1787970, Length=402, Percent_Identity=49.2537313432836, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1789175, Length=396, Percent_Identity=44.1919191919192, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI48994898, Length=383, Percent_Identity=25.5874673629243, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25143064, Length=213, Percent_Identity=29.1079812206573, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=353, Percent_Identity=26.0623229461756, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=28.82096069869, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI20129463, Length=348, Percent_Identity=28.448275862069, Blast_Score=116, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 68958; Mature: 68827

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPEAFALGLPGASPGELAHADLVGRLAREIYRQGQAASQPFAPAIPAGPQVPQALEGL
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCC
PQGPGGAPLPGAPVGVPSAPAGGQPAGLQPDASALPARSFGAPPVGLPGLSGPTLPNRAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCCCCCCCCCCCCCCCCC
ASPAFPDAAAIPPVHPASPRPVLPDFSLAGAPALAAALPGGPELHRQIAADHPRANAFAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCCHHHHHH
ALVPDLVPADPSKAGRDEAPESLARTGRRSRAPEAPAGDYYFLPLGPGPARGAAASPRVE
HHHHHCCCCCCCCCCCCCCHHHHHHCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
PTRYPGPAPRLAAQGSSPVAAPFDVEQVRRDFPALHQSVNGHPLVWLDNAATTHKPQAVI
CCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHH
DATAAFYARHNSNIHRAAHTLAARATDLFEGGREAVRRFLNAPSKDDIVFLRGTTEAINL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHH
VANSYGRAQIGPGDEIIVSTIEHHANIVPWQLLAQQTGATLRVIPVNDRGEIIFEQYAAL
HHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHH
LSGRTKIVSVTQVANALGTVNPVREIIQLAHAYGVPVLVDAAQSSPHMPLDVQSLDADFL
HCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHCCCCEE
VFSGHKVFGPTGIGALYGKTHLLEAMPPWQGGGHMIEDVTFAKTVYKGAPEKFEAGTPDI
EEECCEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCH
AGAVGLGAALDYLAGIGMPAIAAYEHDLLDYAQGGLADVKGLRLIGTAREKASVMSFVIE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCEEEEECHHHHHHHHHHHCC
GQTNEAVAHHLDAHGIAVRSGHHCALPALRRFGVDQSVRASLAFYNTRADVDAFLRALHT
CCCCHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
LPRP
CCCC
>Mature Secondary Structure 
TTPEAFALGLPGASPGELAHADLVGRLAREIYRQGQAASQPFAPAIPAGPQVPQALEGL
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCC
PQGPGGAPLPGAPVGVPSAPAGGQPAGLQPDASALPARSFGAPPVGLPGLSGPTLPNRAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCCCCCCCCCCCCCCCCC
ASPAFPDAAAIPPVHPASPRPVLPDFSLAGAPALAAALPGGPELHRQIAADHPRANAFAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCCHHHHHH
ALVPDLVPADPSKAGRDEAPESLARTGRRSRAPEAPAGDYYFLPLGPGPARGAAASPRVE
HHHHHCCCCCCCCCCCCCCHHHHHHCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
PTRYPGPAPRLAAQGSSPVAAPFDVEQVRRDFPALHQSVNGHPLVWLDNAATTHKPQAVI
CCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHH
DATAAFYARHNSNIHRAAHTLAARATDLFEGGREAVRRFLNAPSKDDIVFLRGTTEAINL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHH
VANSYGRAQIGPGDEIIVSTIEHHANIVPWQLLAQQTGATLRVIPVNDRGEIIFEQYAAL
HHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHH
LSGRTKIVSVTQVANALGTVNPVREIIQLAHAYGVPVLVDAAQSSPHMPLDVQSLDADFL
HCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHCCCCEE
VFSGHKVFGPTGIGALYGKTHLLEAMPPWQGGGHMIEDVTFAKTVYKGAPEKFEAGTPDI
EEECCEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCH
AGAVGLGAALDYLAGIGMPAIAAYEHDLLDYAQGGLADVKGLRLIGTAREKASVMSFVIE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCEEEEECHHHHHHHHHHHCC
GQTNEAVAHHLDAHGIAVRSGHHCALPALRRFGVDQSVRASLAFYNTRADVDAFLRALHT
CCCCHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
LPRP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA