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The map label for this gene is galE [H]

Identifier: 170747653

GI number: 170747653

Start: 1290057

End: 1290989

Strand: Reverse

Name: galE [H]

Synonym: Mrad2831_1226

Alternate gene names: 170747653

Gene position: 1290989-1290057 (Counterclockwise)

Preceding gene: 170747654

Following gene: 170747652

Centisome position: 21.24

GC content: 66.13

Gene sequence:

>933_bases
ATGCGAATTCTGATCACCGGCGGCGCGGGTTACATCGGGACGATCCTGGTGCCCATGCTTCTGGAGCGCGGGCATAACGT
TACGGTGCTCGACACGTTCAAGTCCGGCGCCCCGGACCTGTTCTCGGCCTGCCAGTACGACACGTTCGAGCCGATCAAGG
GTGACGCGCGCGACACGCGTATCCTGGACGAGCTGATCCCGAAGCACGACGTGCTCATCCCCCTCGCCGCCCTGGTCGGC
GCGCCTCTGTGCAAGGAGGACGCGATCGGCGCCACGACGCTCAACCGCGACGCCGTGGTCGCGCTGGCGCAGCGCGCGGG
CGGCGACCAGAGGATCGTCTACCCGACGACCAACTCGGGCTACGGCGTCGGCGAGGCCGGCAAGTTCTGCACCGAGGACT
CGCCCCTGCGGCCGATCTCGCTCTACGGCACCACCAAGGTCGAGGCCGAGAAGGCCGTGCTCGACAGCGGGCGCGGCGTC
AGCCTGCGGCTCGCGACGGTGTTCGGCATGGCGCCGCGCATGCGGCTCGACCTCCTCGTCAACGACTTCACCCACCGGGC
CGTGACCGACCGGGCGCTCCTGGTCTTCGAGGGCCACTTCAAGCGCAACTACATCCACATCCGTGACGTCGCCAAAGGGT
TCATCCACGCGATGGACAATTACGACCAGATGCGCGGAGAGGCGTACAATCTCGGCCTGTCGAGCGCCAACCTGTCGAAG
CTGGAGCTCTGCGAGCGCATCAAGGCGCACGTTCCGAACTTCGTCTACGTCGAGGCCCCGATCGGCGAGGACCCGGACAA
GCGCGACTACATCGTGTCCAACGAGAAGCTGGAGGCGACTGGCTGGTTCCCCGATTTCGACCTCGACCGGGGCATCAAGG
AGCTGATCAAGGGCTTCCGGATGATCCGCAACTCGCGGTTCGCCAACGTCTGA

Upstream 100 bases:

>100_bases
GGGTCCACCCTGATCTATCGCCAGACGCGCTGAGTGGCGTCCTCACAGGCCCCAGCCCGGCCGCAGCCGGGCCGCGGACC
CATCGCGACGAGAGGCAACG

Downstream 100 bases:

>100_bases
TCGGGATGGGCGGAGCCTGCAGCGAACGCGCCGCCGGTCGGCCCTACACGGCGGCCGGCGCGGGAACGGACCGAGGTTAT
CATGAGCGCGATCGTCGATT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRILITGGAGYIGTILVPMLLERGHNVTVLDTFKSGAPDLFSACQYDTFEPIKGDARDTRILDELIPKHDVLIPLAALVG
APLCKEDAIGATTLNRDAVVALAQRAGGDQRIVYPTTNSGYGVGEAGKFCTEDSPLRPISLYGTTKVEAEKAVLDSGRGV
SLRLATVFGMAPRMRLDLLVNDFTHRAVTDRALLVFEGHFKRNYIHIRDVAKGFIHAMDNYDQMRGEAYNLGLSSANLSK
LELCERIKAHVPNFVYVEAPIGEDPDKRDYIVSNEKLEATGWFPDFDLDRGIKELIKGFRMIRNSRFANV

Sequences:

>Translated_310_residues
MRILITGGAGYIGTILVPMLLERGHNVTVLDTFKSGAPDLFSACQYDTFEPIKGDARDTRILDELIPKHDVLIPLAALVG
APLCKEDAIGATTLNRDAVVALAQRAGGDQRIVYPTTNSGYGVGEAGKFCTEDSPLRPISLYGTTKVEAEKAVLDSGRGV
SLRLATVFGMAPRMRLDLLVNDFTHRAVTDRALLVFEGHFKRNYIHIRDVAKGFIHAMDNYDQMRGEAYNLGLSSANLSK
LELCERIKAHVPNFVYVEAPIGEDPDKRDYIVSNEKLEATGWFPDFDLDRGIKELIKGFRMIRNSRFANV
>Mature_310_residues
MRILITGGAGYIGTILVPMLLERGHNVTVLDTFKSGAPDLFSACQYDTFEPIKGDARDTRILDELIPKHDVLIPLAALVG
APLCKEDAIGATTLNRDAVVALAQRAGGDQRIVYPTTNSGYGVGEAGKFCTEDSPLRPISLYGTTKVEAEKAVLDSGRGV
SLRLATVFGMAPRMRLDLLVNDFTHRAVTDRALLVFEGHFKRNYIHIRDVAKGFIHAMDNYDQMRGEAYNLGLSSANLSK
LELCERIKAHVPNFVYVEAPIGEDPDKRDYIVSNEKLEATGWFPDFDLDRGIKELIKGFRMIRNSRFANV

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=320, Percent_Identity=28.125, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356223, Length=325, Percent_Identity=26.4615384615385, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34261; Mature: 34261

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILITGGAGYIGTILVPMLLERGHNVTVLDTFKSGAPDLFSACQYDTFEPIKGDARDTR
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCCHHHH
ILDELIPKHDVLIPLAALVGAPLCKEDAIGATTLNRDAVVALAQRAGGDQRIVYPTTNSG
HHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEECCCCC
YGVGEAGKFCTEDSPLRPISLYGTTKVEAEKAVLDSGRGVSLRLATVFGMAPRMRLDLLV
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHH
NDFTHRAVTDRALLVFEGHFKRNYIHIRDVAKGFIHAMDNYDQMRGEAYNLGLSSANLSK
HHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCHH
LELCERIKAHVPNFVYVEAPIGEDPDKRDYIVSNEKLEATGWFPDFDLDRGIKELIKGFR
HHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHHH
MIRNSRFANV
HHHCCCCCCC
>Mature Secondary Structure
MRILITGGAGYIGTILVPMLLERGHNVTVLDTFKSGAPDLFSACQYDTFEPIKGDARDTR
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCCHHHH
ILDELIPKHDVLIPLAALVGAPLCKEDAIGATTLNRDAVVALAQRAGGDQRIVYPTTNSG
HHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEECCCCC
YGVGEAGKFCTEDSPLRPISLYGTTKVEAEKAVLDSGRGVSLRLATVFGMAPRMRLDLLV
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHH
NDFTHRAVTDRALLVFEGHFKRNYIHIRDVAKGFIHAMDNYDQMRGEAYNLGLSSANLSK
HHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCHH
LELCERIKAHVPNFVYVEAPIGEDPDKRDYIVSNEKLEATGWFPDFDLDRGIKELIKGFR
HHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHHH
MIRNSRFANV
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8921853; 12948626 [H]