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The map label for this gene is cya1 [H]

Identifier: 170747418

GI number: 170747418

Start: 1042062

End: 1043264

Strand: Reverse

Name: cya1 [H]

Synonym: Mrad2831_0986

Alternate gene names: 170747418

Gene position: 1043264-1042062 (Counterclockwise)

Preceding gene: 170747427

Following gene: 170747416

Centisome position: 17.17

GC content: 74.15

Gene sequence:

>1203_bases
ATGGACCTGACGCATCTGGGGCGCTGGATCGCCGCGCACGCCACGGCGACCGACGACCACGACACCCTGCTCGCGGGCTT
CTGCGAGTCGCTGGTCGAGGCCGGCCTCCCCGTCTGGCGGGTCAGCGTCATGGCGCCGGCCCTGGACCCGACGCTGCGCG
GCGTCAGCCTGAACTGGCACGCGGGCGAGGGCATGTCCTTCGTCGCCAACGCCCACGGCGCCGACGAGGAGAGCGACTGG
CTCCTGAGCCCGGTCTACGCCCTGGTGGAGAAGGGCGAGACCTTCGGCCGCTGGCGCCTCGACGCGCCCGGGCTGGCGGT
GGACTTCCCGGTCCTGAACGCCCTCGGGGCGCAGGGCGGCGTCGACTACGTGCTGCACATCGCCGAGTTCGCCCCCGGCA
CCGCGCTGCGGGGCATCGCGGTCTCGTTCTGCACCCGCGCCGCCGCCGGCTTCACCGGGGCGGACCTCGCCGCGATCGCC
GATGTCCTGCCGTTCCTGACGCTGGCGATGGCCAAGATGGGCCTCGCCCACACGTTCCGGGAAGTGTCGGCCACCTATCT
CGGCCGGTCCACCGCCGAGCGCATCCTCGACGGCCAGATCCGGCGCGGCGAGGGGCGGGCCGTGCCGGCGGCGATCCTGC
TGACCGACCTCCGGGGCTTCACGGCCCTGGCCGACCGGGTGGATCCCGCCGACATGGTCACGTGGCTCAACGAGCACTTC
GACGCCCTCGGCGACCCGGTGGCGCGGCACGGCGGCGAGATCCTGAAATTCCTCGGCGACGGCTTCCTGGCGATCTTCCC
GGTCCCGGACGCCGACACCCTGCCCTGCCCGGTCTGCGGCGGCGCCCTCGACGCCGCGACCGAGGGGCTCGCCGCCAACG
CGGCGCTCAACGCCCGCCGCCGCGCCGCGGGGCTGCCCGAGCTCCCGGCCGAGTGCGTCGTCCATTTCGGGACGGTCATC
TACGGCAATGTCGGCACGGAGCGGCGCCTCGACTTCACGATCATCGGGCGGGCGGTCAACGAGGCCAGCCGGATCGAGAG
CCAGTGCGCGGCCCTCGGCCACGAGCTCCTCGTGTCGGACTCCTTCGCCGAACGGTGCGCCCGGCCGCTGGAGCCGGTCG
GGACGATCGAGCTCCGGGGCCTGTCGCGGCCGATGCGGGTCTGGACCGTGCCGGGCGAGCCGTCCGGTGCGGCGACGGCC
TGA

Upstream 100 bases:

>100_bases
CGCGGAAAGGTTAACGGTTCTTTTCGATCGCGCCGCGGTCGGGACAGGGCCGGGTCGGGGCCGGACCGCGGCCGGCACGG
ACAGGGGGCGAGCCTGAGGC

Downstream 100 bases:

>100_bases
GGAGGCGGAGATCCTCCGTCCGAGTCGAGCGGACGAGCGGGCGGATCGGCGCCGCCCTCAGAACAGCGCGCAGCTCCGCT
GCAGCACCAAGCCGACCGCG

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MDLTHLGRWIAAHATATDDHDTLLAGFCESLVEAGLPVWRVSVMAPALDPTLRGVSLNWHAGEGMSFVANAHGADEESDW
LLSPVYALVEKGETFGRWRLDAPGLAVDFPVLNALGAQGGVDYVLHIAEFAPGTALRGIAVSFCTRAAAGFTGADLAAIA
DVLPFLTLAMAKMGLAHTFREVSATYLGRSTAERILDGQIRRGEGRAVPAAILLTDLRGFTALADRVDPADMVTWLNEHF
DALGDPVARHGGEILKFLGDGFLAIFPVPDADTLPCPVCGGALDAATEGLAANAALNARRRAAGLPELPAECVVHFGTVI
YGNVGTERRLDFTIIGRAVNEASRIESQCAALGHELLVSDSFAERCARPLEPVGTIELRGLSRPMRVWTVPGEPSGAATA

Sequences:

>Translated_400_residues
MDLTHLGRWIAAHATATDDHDTLLAGFCESLVEAGLPVWRVSVMAPALDPTLRGVSLNWHAGEGMSFVANAHGADEESDW
LLSPVYALVEKGETFGRWRLDAPGLAVDFPVLNALGAQGGVDYVLHIAEFAPGTALRGIAVSFCTRAAAGFTGADLAAIA
DVLPFLTLAMAKMGLAHTFREVSATYLGRSTAERILDGQIRRGEGRAVPAAILLTDLRGFTALADRVDPADMVTWLNEHF
DALGDPVARHGGEILKFLGDGFLAIFPVPDADTLPCPVCGGALDAATEGLAANAALNARRRAAGLPELPAECVVHFGTVI
YGNVGTERRLDFTIIGRAVNEASRIESQCAALGHELLVSDSFAERCARPLEPVGTIELRGLSRPMRVWTVPGEPSGAATA
>Mature_400_residues
MDLTHLGRWIAAHATATDDHDTLLAGFCESLVEAGLPVWRVSVMAPALDPTLRGVSLNWHAGEGMSFVANAHGADEESDW
LLSPVYALVEKGETFGRWRLDAPGLAVDFPVLNALGAQGGVDYVLHIAEFAPGTALRGIAVSFCTRAAAGFTGADLAAIA
DVLPFLTLAMAKMGLAHTFREVSATYLGRSTAERILDGQIRRGEGRAVPAAILLTDLRGFTALADRVDPADMVTWLNEHF
DALGDPVARHGGEILKFLGDGFLAIFPVPDADTLPCPVCGGALDAATEGLAANAALNARRRAAGLPELPAECVVHFGTVI
YGNVGTERRLDFTIIGRAVNEASRIESQCAALGHELLVSDSFAERCARPLEPVGTIELRGLSRPMRVWTVPGEPSGAATA

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 42219; Mature: 42219

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTHLGRWIAAHATATDDHDTLLAGFCESLVEAGLPVWRVSVMAPALDPTLRGVSLNWH
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCEEEEEE
AGEGMSFVANAHGADEESDWLLSPVYALVEKGETFGRWRLDAPGLAVDFPVLNALGAQGG
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCEECHHHHHHHCCCCC
VDYVLHIAEFAPGTALRGIAVSFCTRAAAGFTGADLAAIADVLPFLTLAMAKMGLAHTFR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVSATYLGRSTAERILDGQIRRGEGRAVPAAILLTDLRGFTALADRVDPADMVTWLNEHF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DALGDPVARHGGEILKFLGDGFLAIFPVPDADTLPCPVCGGALDAATEGLAANAALNARR
HHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHH
RAAGLPELPAECVVHFGTVIYGNVGTERRLDFTIIGRAVNEASRIESQCAALGHELLVSD
HHCCCCCCCHHHHHHHHHHEECCCCCCCEEEHEEEHHHHHHHHHHHHHHHHHHHHHHHCC
SFAERCARPLEPVGTIELRGLSRPMRVWTVPGEPSGAATA
HHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MDLTHLGRWIAAHATATDDHDTLLAGFCESLVEAGLPVWRVSVMAPALDPTLRGVSLNWH
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCEEEEEE
AGEGMSFVANAHGADEESDWLLSPVYALVEKGETFGRWRLDAPGLAVDFPVLNALGAQGG
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCEECHHHHHHHCCCCC
VDYVLHIAEFAPGTALRGIAVSFCTRAAAGFTGADLAAIADVLPFLTLAMAKMGLAHTFR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVSATYLGRSTAERILDGQIRRGEGRAVPAAILLTDLRGFTALADRVDPADMVTWLNEHF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DALGDPVARHGGEILKFLGDGFLAIFPVPDADTLPCPVCGGALDAATEGLAANAALNARR
HHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHH
RAAGLPELPAECVVHFGTVIYGNVGTERRLDFTIIGRAVNEASRIESQCAALGHELLVSD
HHCCCCCCCHHHHHHHHHHEECCCCCCCEEEHEEEHHHHHHHHHHHHHHHHHHHHHHHCC
SFAERCARPLEPVGTIELRGLSRPMRVWTVPGEPSGAATA
HHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]