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The map label for this gene is queF [H]

Identifier: 170747416

GI number: 170747416

Start: 1039667

End: 1040155

Strand: Reverse

Name: queF [H]

Synonym: Mrad2831_0983

Alternate gene names: 170747416

Gene position: 1040155-1039667 (Counterclockwise)

Preceding gene: 170747418

Following gene: 170747414

Centisome position: 17.11

GC content: 69.94

Gene sequence:

>489_bases
ATGCGCGCGGGGCCGGCAGGCTCTATATGGCCGGCCATGACCTCCACCGACGATCTCCAGCTCGGCCAGCCGACACCCTT
CCCCACCTCGCCCGAGGAGGCGCGGCTCGACCGGGTCCCGAACCCGCACGCGGACACCGACTACGTCGCCCGGTTCACCG
CGCCCGAATTCACCTCGATCTGCCCGGTCACCGGGCAGCCGGACTTCGCGATCCTCGTGATCGACTACGTGCCCGGCGAC
TGGCTCGTGGAGTCGAAGTCGCTGAAGCTCTACCTCGGGTCGTTCCGCAACCACGGCGCGTTCCACGAGGATTGCACGGT
GGCGATCGGCAAGCGGCTCCGCGACCTCTTGGAGCCGCGCTACCTGCGCATCGGCGGCTTCTGGTATCCCCGCGGCGGCA
TCCCGATCGACGTGTTCTGGCAGACGGGCGAGCTGCCGAAGAACGCGTGGCTGCCGGACCCGGGCGTCCCGCCCTACCGC
GGACGCTGA

Upstream 100 bases:

>100_bases
GCATCGCGGCGGCTTATCCGTCAAGCCGCGGCCGGCGGCAAGCGCCGGGACGGGCGGCGCACAGCCGGGTTCACCCGGGA
AAGCCTCGCGGATCAGGCGG

Downstream 100 bases:

>100_bases
CCGGACAGACGAAAAGGGCGACCCGCTCGCGCCGGTCGCCCCCGATCCTCGTCGGATCTCCGATCTCAGTAGCCGTAGCC
GTAGTAGCCGTAGCCCGGGG

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRAGPAGSIWPAMTSTDDLQLGQPTPFPTSPEEARLDRVPNPHADTDYVARFTAPEFTSICPVTGQPDFAILVIDYVPGD
WLVESKSLKLYLGSFRNHGAFHEDCTVAIGKRLRDLLEPRYLRIGGFWYPRGGIPIDVFWQTGELPKNAWLPDPGVPPYR
GR

Sequences:

>Translated_162_residues
MRAGPAGSIWPAMTSTDDLQLGQPTPFPTSPEEARLDRVPNPHADTDYVARFTAPEFTSICPVTGQPDFAILVIDYVPGD
WLVESKSLKLYLGSFRNHGAFHEDCTVAIGKRLRDLLEPRYLRIGGFWYPRGGIPIDVFWQTGELPKNAWLPDPGVPPYR
GR
>Mature_162_residues
MRAGPAGSIWPAMTSTDDLQLGQPTPFPTSPEEARLDRVPNPHADTDYVARFTAPEFTSICPVTGQPDFAILVIDYVPGD
WLVESKSLKLYLGSFRNHGAFHEDCTVAIGKRLRDLLEPRYLRIGGFWYPRGGIPIDVFWQTGELPKNAWLPDPGVPPYR
GR

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 18095; Mature: 18095

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGPAGSIWPAMTSTDDLQLGQPTPFPTSPEEARLDRVPNPHADTDYVARFTAPEFTSI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCEE
CPVTGQPDFAILVIDYVPGDWLVESKSLKLYLGSFRNHGAFHEDCTVAIGKRLRDLLEPR
CCCCCCCCEEEEEEEECCCCEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
YLRIGGFWYPRGGIPIDVFWQTGELPKNAWLPDPGVPPYRGR
EEEECCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRAGPAGSIWPAMTSTDDLQLGQPTPFPTSPEEARLDRVPNPHADTDYVARFTAPEFTSI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCEE
CPVTGQPDFAILVIDYVPGDWLVESKSLKLYLGSFRNHGAFHEDCTVAIGKRLRDLLEPR
CCCCCCCCEEEEEEEECCCCEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
YLRIGGFWYPRGGIPIDVFWQTGELPKNAWLPDPGVPPYRGR
EEEECCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA