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The map label for this gene is engA

Identifier: 170762344

GI number: 170762344

Start: 440505

End: 441833

Strand: Reverse

Name: engA

Synonym: UPA3_0399

Alternate gene names: 170762344

Gene position: 441833-440505 (Counterclockwise)

Preceding gene: 170762431

Following gene: 170761995

Centisome position: 58.78

GC content: 28.22

Gene sequence:

>1329_bases
ATGCGAACTATTGCTATTGTCGGAAAGCCAAATGTTGGTAAATCATCATTATTTAATCGTATTTTAATGCGCCGTAAATC
AATTGTTGACGATCAGCCAGGAGTAACAAGAGATCGAATATATGATATTGGTAATTGATTAACGCGAAGCTTTATGTTGA
TTGATACAGGAGGTATAATTAGCTCAAAAGATACTTATCAAGATAACATCAATGAACAAGTTTTATTTGCGATTAATGAA
GCAAATACAATTATTTTTTTAGTCTCAGCAAAAGATGGAATTAATAATGATGATAAAAAAATAGCTAAAATGTTAAAAGA
AAAAGCTAAAGATAAAAAAATTATTTTAGTTATAAATAAGATCGAATCAGAAAAATATTATCTTAATGAAGGAGAACTAT
ATTCGTTTGGGTTTGGTAAATTTTTTAAAATCTCAGCTGAGCATGGAATAGGAATGGGTGATCTTTTAGATGAATTAGTA
AAAGATATGCCTATACAAAATAATTTAGAAAAACAAGAACGCTTTAAATTTTGCATTATTGGAAGACCAAATGTTGGTAA
AAGTTCACTAACAAATACCATCTTAGGTGAGCAAAGAGTAATTGTTAATGCTGAAGCAGGTTCAACACGTGATTCAATCG
ATAATGATTTTAATTACTATAATAAAAAATATACAATCATTGACACTGCAGGAATACGACGAAAAGGTAAAATTGTCGAA
TCTGTTGAAAAATATGCTGTATTACGAACTAAAAAAGCAATTGAAAGATCCCAATTAATTTTATTAGTACTTGATGGATC
TGAACCTTTTAAAGAACAAGATGAAGTTGTTGGTGGTTTAGCATATAATGCAAATATTCCAACAATTATTATTGTTAATA
AATGAGATAATATTATTAACAAAAATAGTCATACAATGGAAATGGTAAAAAAACAGATTCGTTCACAATTTAAGTATTTA
TCATGAGCACCAATTGTTTTTGTTAGTGCTTTAGACAATAAAAGAATTCACACTATTTTTGAAGCAATTGAATTCGTTCG
TGAGCAAGCAATGCGCAAAATTGCAACTTCATTATTAAATGATGTTGTTATTAAAGCAAATGCTTTTCAAGAACCACCAC
CATTTAAAGGAGGGAGAATCAGTATTTCATATATCGTTCAAGTACAATCACAAATCCCTACTTTTGTTTTAAAATGTAAT
AACCCTAAATTTTTGCACTTTAGCTATGCTCGATATATTGAAAATGAAATTCGTAAAGCTTTTGGATTTGATAGTGTACC
AATAACATTATATTGACAAGATAAAAATAAAAAATTACGAGGAGAATAA

Upstream 100 bases:

>100_bases
GAAATAATTTATATTCAAAATATGAAAGCTTAATCAAACATTATTAAATTGTTTTTTATTATAATTACATATAATGTTTG
TGATTAAAAAGGAATAATCT

Downstream 100 bases:

>100_bases
AATAATAATGAGTAAAATTTTAATTGTTGGAAGCGGAGCTTTTGGAAGTGCTTTAACACAAGTTTTAGTTTCAAATTCTC
ATATTGTTGATGTTTATGGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDIGNWLTRSFMLIDTGGIISSKDTYQDNINEQVLFAINE
ANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKIILVINKIESEKYYLNEGELYSFGFGKFFKISAEHGIGMGDLLDELV
KDMPIQNNLEKQERFKFCIIGRPNVGKSSLTNTILGEQRVIVNAEAGSTRDSIDNDFNYYNKKYTIIDTAGIRRKGKIVE
SVEKYAVLRTKKAIERSQLILLVLDGSEPFKEQDEVVGGLAYNANIPTIIIVNKWDNIINKNSHTMEMVKKQIRSQFKYL
SWAPIVFVSALDNKRIHTIFEAIEFVREQAMRKIATSLLNDVVIKANAFQEPPPFKGGRISISYIVQVQSQIPTFVLKCN
NPKFLHFSYARYIENEIRKAFGFDSVPITLYWQDKNKKLRGE

Sequences:

>Translated_442_residues
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDIGN*LTRSFMLIDTGGIISSKDTYQDNINEQVLFAINE
ANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKIILVINKIESEKYYLNEGELYSFGFGKFFKISAEHGIGMGDLLDELV
KDMPIQNNLEKQERFKFCIIGRPNVGKSSLTNTILGEQRVIVNAEAGSTRDSIDNDFNYYNKKYTIIDTAGIRRKGKIVE
SVEKYAVLRTKKAIERSQLILLVLDGSEPFKEQDEVVGGLAYNANIPTIIIVNK*DNIINKNSHTMEMVKKQIRSQFKYL
S*APIVFVSALDNKRIHTIFEAIEFVREQAMRKIATSLLNDVVIKANAFQEPPPFKGGRISISYIVQVQSQIPTFVLKCN
NPKFLHFSYARYIENEIRKAFGFDSVPITLY*QDKNKKLRGE
>Mature_442_residues
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDIGN*LTRSFMLIDTGGIISSKDTYQDNINEQVLFAINE
ANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKIILVINKIESEKYYLNEGELYSFGFGKFFKISAEHGIGMGDLLDELV
KDMPIQNNLEKQERFKFCIIGRPNVGKSSLTNTILGEQRVIVNAEAGSTRDSIDNDFNYYNKKYTIIDTAGIRRKGKIVE
SVEKYAVLRTKKAIERSQLILLVLDGSEPFKEQDEVVGGLAYNANIPTIIIVNK*DNIINKNSHTMEMVKKQIRSQFKYL
S*APIVFVSALDNKRIHTIFEAIEFVREQAMRKIATSLLNDVVIKANAFQEPPPFKGGRISISYIVQVQSQIPTFVLKCN
NPKFLHFSYARYIENEIRKAFGFDSVPITLY*QDKNKKLRGE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=34.7252747252747, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI2367268, Length=135, Percent_Identity=32.5925925925926, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=33.5260115606936, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49731; Mature: 49731

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDIGNLTRSFMLIDTGGIIS
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCC
SKDTYQDNINEQVLFAINEANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKIILVINKI
CCCCHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEC
ESEKYYLNEGELYSFGFGKFFKISAEHGIGMGDLLDELVKDMPIQNNLEKQERFKFCIIG
CCCEEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHCCEEEEEE
RPNVGKSSLTNTILGEQRVIVNAEAGSTRDSIDNDFNYYNKKYTIIDTAGIRRKGKIVES
CCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEEEECCCCCCCCHHHHH
VEKYAVLRTKKAIERSQLILLVLDGSEPFKEQDEVVGGLAYNANIPTIIIVNKDNIINKN
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCCCCC
SHTMEMVKKQIRSQFKYLSAPIVFVSALDNKRIHTIFEAIEFVREQAMRKIATSLLNDVV
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IKANAFQEPPPFKGGRISISYIVQVQSQIPTFVLKCNNPKFLHFSYARYIENEIRKAFGF
EEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCC
DSVPITLYQDKNKKLRGE
CCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDIGNLTRSFMLIDTGGIIS
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCC
SKDTYQDNINEQVLFAINEANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKIILVINKI
CCCCHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEC
ESEKYYLNEGELYSFGFGKFFKISAEHGIGMGDLLDELVKDMPIQNNLEKQERFKFCIIG
CCCEEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHCCEEEEEE
RPNVGKSSLTNTILGEQRVIVNAEAGSTRDSIDNDFNYYNKKYTIIDTAGIRRKGKIVES
CCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHCCCEEEEEECCCCCCCCHHHHH
VEKYAVLRTKKAIERSQLILLVLDGSEPFKEQDEVVGGLAYNANIPTIIIVNKDNIINKN
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCCCCC
SHTMEMVKKQIRSQFKYLSAPIVFVSALDNKRIHTIFEAIEFVREQAMRKIATSLLNDVV
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IKANAFQEPPPFKGGRISISYIVQVQSQIPTFVLKCNNPKFLHFSYARYIENEIRKAFGF
EEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCC
DSVPITLYQDKNKKLRGE
CCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA