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The map label for this gene is lspA [H]

Identifier: 170762336

GI number: 170762336

Start: 357863

End: 358654

Strand: Reverse

Name: lspA [H]

Synonym: UPA3_0329

Alternate gene names: 170762336

Gene position: 358654-357863 (Counterclockwise)

Preceding gene: 170762324

Following gene: 170762382

Centisome position: 47.71

GC content: 23.48

Gene sequence:

>792_bases
ATGCTTCAAAAAATCAAAAATTCAAATTTTTATATAATAATTAAAAAATTTAATCAATCACTTAGAAAAATAAATTTTTT
TGAGAAAATTATTTTAAAAATAAACAATAAAAGCATTCGTGATTACTTTTTATCAATAACATCATTAGATGTAATTTTTT
ATAAAATAATTAATTTTATTATTGTTGCTTTAATTGTGCTATTATCAGGTTTTTTGGTTCGTGAATGAGCTATTGATTTA
GTTGTCAAAACAAAAGAAACGCATCATGGTCCTATTTTTCATTTTACACTTAATAATGGGATTGCTCTTGGTAGAATTAA
TAACCATAGCGGAATTGTTTATACTTTACAATCAATCCCCATCATATTAGGATTTTTATCATTTATTTTTTTAAAAAATT
CTTGTTATTATGTTCCATTGCTTTTTCTATTATTTGGCGGTTTAGGAAATATTATTGATCGCTCAATTCCAGAATTTGAA
TTATTCAATGCTTTACCAAATATATTTCACAATAGCCTTATAAATCCTAATAGTGTTGGTGGAGGCGATGATGTTATTAA
TGGTGTTGTTGATTATTGAAAATTTGTTAATAGTATAATTAATCTTTTTGATGTTTATATTGTTGTTGGTGTTTGTGTAT
TAGTTGTTATTTTAGTTATTAGATTTATTATCAAATGAAAAAATGATAGTGATAATCAAGACATTATAAAAAAAGTTGCC
GATGAGAATGATTTAGAAATCAACGAAATTTCTAACAAACCATTCGGATATGATGACTTAAAAAAATCATAG

Upstream 100 bases:

>100_bases
ATGAAGAATGTGTTCTTTTAATGAAAGAATATGGCCATCTTAAAAAAGATGAATTTGTAACTAAAATGATGAAAGAACGT
CCAGAAAAGTACATTAAATA

Downstream 100 bases:

>100_bases
CAATGAAAATACTATATTCTTTAATGTCGTCTCAACGCATCGATAAATTTTTAGTAGAAAATACTAATTATTCACGAACA
TTAATTAAAAAAATGTTAGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLQKIKNSNFYIIIKKFNQSLRKINFFEKIILKINNKSIRDYFLSITSLDVIFYKIINFIIVALIVLLSGFLVREWAIDL
VVKTKETHHGPIFHFTLNNGIALGRINNHSGIVYTLQSIPIILGFLSFIFLKNSCYYVPLLFLLFGGLGNIIDRSIPEFE
LFNALPNIFHNSLINPNSVGGGDDVINGVVDYWKFVNSIINLFDVYIVVGVCVLVVILVIRFIIKWKNDSDNQDIIKKVA
DENDLEINEISNKPFGYDDLKKS

Sequences:

>Translated_263_residues
MLQKIKNSNFYIIIKKFNQSLRKINFFEKIILKINNKSIRDYFLSITSLDVIFYKIINFIIVALIVLLSGFLVRE*AIDL
VVKTKETHHGPIFHFTLNNGIALGRINNHSGIVYTLQSIPIILGFLSFIFLKNSCYYVPLLFLLFGGLGNIIDRSIPEFE
LFNALPNIFHNSLINPNSVGGGDDVINGVVDY*KFVNSIINLFDVYIVVGVCVLVVILVIRFIIK*KNDSDNQDIIKKVA
DENDLEINEISNKPFGYDDLKKS
>Mature_263_residues
MLQKIKNSNFYIIIKKFNQSLRKINFFEKIILKINNKSIRDYFLSITSLDVIFYKIINFIIVALIVLLSGFLVRE*AIDL
VVKTKETHHGPIFHFTLNNGIALGRINNHSGIVYTLQSIPIILGFLSFIFLKNSCYYVPLLFLLFGGLGNIIDRSIPEFE
LFNALPNIFHNSLINPNSVGGGDDVINGVVDY*KFVNSIINLFDVYIVVGVCVLVVILVIRFIIK*KNDSDNQDIIKKVA
DENDLEINEISNKPFGYDDLKKS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 29525; Mature: 29525

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKIKNSNFYIIIKKFNQSLRKINFFEKIILKINNKSIRDYFLSITSLDVIFYKIINFI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IVALIVLLSGFLVREAIDLVVKTKETHHGPIFHFTLNNGIALGRINNHSGIVYTLQSIPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCEEEEHHHHHH
ILGFLSFIFLKNSCYYVPLLFLLFGGLGNIIDRSIPEFELFNALPNIFHNSLINPNSVGG
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GDDVINGVVDYKFVNSIINLFDVYIVVGVCVLVVILVIRFIIKKNDSDNQDIIKKVADEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
DLEINEISNKPFGYDDLKKS
CCCHHHCCCCCCCCHHCCCC
>Mature Secondary Structure
MLQKIKNSNFYIIIKKFNQSLRKINFFEKIILKINNKSIRDYFLSITSLDVIFYKIINFI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IVALIVLLSGFLVREAIDLVVKTKETHHGPIFHFTLNNGIALGRINNHSGIVYTLQSIPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCEEEEHHHHHH
ILGFLSFIFLKNSCYYVPLLFLLFGGLGNIIDRSIPEFELFNALPNIFHNSLINPNSVGG
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GDDVINGVVDYKFVNSIINLFDVYIVVGVCVLVVILVIRFIIKKNDSDNQDIIKKVADEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
DLEINEISNKPFGYDDLKKS
CCCHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12466555 [H]