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The map label for this gene is rhtA [H]

Identifier: 170684270

GI number: 170684270

Start: 840889

End: 841776

Strand: Reverse

Name: rhtA [H]

Synonym: EcSMS35_0837

Alternate gene names: 170684270

Gene position: 841776-840889 (Counterclockwise)

Preceding gene: 170680896

Following gene: 170682007

Centisome position: 16.61

GC content: 53.6

Gene sequence:

>888_bases
ATGCCTGGTTCATTACGTAAAATGCCGGTCTGGTTACCAATAGTCATATTGCTCGTTGCCATGGCGTCTATTCAGGGTGG
AGCCTCGTTAGCTAAGTCACTTTTTCCTCTGGTGGGCGCACCGGGGGTCACTGCGCTGCGTCTGGCATTAGGCACGCTGA
TCCTCATCGCGTTCTTTAAGCCATGGCGACTGCGCTTTGCCAAAGAGCAGCGGTTACTGCTGTTGTTTTACGGCGTTTCG
CTGGGGGGGATGAATTATCTTTTTTATCTTTCTATTCAGACGGTACCGCTGGGTATTGCGGTGGCGCTGGAGTTCACCGG
ACCACTGGCGGTGGCGCTGTTCTCTTCTCGTCGCCCGGTAGATTTCGTCTGGGTTGTTCTGGCGGTTCTTGGTCTGTGGT
TCCTGCTACCGCTGGGGCAAGACGTTTCCCATGTCGATTTAACCGGCTGTGCGCTGGCTCTGGGGGCCGGGGCTTGTTGG
GCTATTTACATTTTAAGTGGGCAACGCGCAGGAGCGGAACATGGCCCTGCGACGGTGGCAATTGGTTCGTTGATTGCAGC
GTTAATTTTCGTGCCAATTGGAGTGCTTCAGGCTGGTGAAGCACTCTGGCACTGGTCGGTTATTCCATTGGGTCTGGCGG
TCGCTATTCTCTCGACCGCTCTGCCTTATTCGCTGGAAATGATTGCCCTCACCCGTTTGCCAACACGCACATTTGGTACG
CTAATGAGCATGGAACCTGCGCTGGCTGCCGTTTCCGGGATGATTTTCCTCGGAGAAACACTGACACCCATACAGCTGCT
GGCGCTCGGCGCTATCATCGCCGCTTCAATGGGTTCTACGCTGACAGTACGCAAAGAGAGCAAAATAAAAGAATTAGACA
TAAATTAA

Upstream 100 bases:

>100_bases
CAAAACGGGGGAAAATTTTTTCAACAAATGCTCAACCAGCATTGGGTATATCCAGTACACTCCACGCTTTACTTAGGTTT
AGATATTTGTGGGAGAAAGG

Downstream 100 bases:

>100_bases
ATTTACATTTCTGCATGGTTATGCATAACCATGCAGATTTTCTCGCTACTTTTCCTCTACACCGTCTTTATATATCGAAT
TATGCAAAAGCATATTTATT

Product: threonine and homoserine efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVTALRLALGTLILIAFFKPWRLRFAKEQRLLLLFYGVS
LGGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGVLQAGEALWHWSVIPLGLAVAILSTALPYSLEMIALTRLPTRTFGT
LMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAASMGSTLTVRKESKIKELDIN

Sequences:

>Translated_295_residues
MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVTALRLALGTLILIAFFKPWRLRFAKEQRLLLLFYGVS
LGGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGVLQAGEALWHWSVIPLGLAVAILSTALPYSLEMIALTRLPTRTFGT
LMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAASMGSTLTVRKESKIKELDIN
>Mature_294_residues
PGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVTALRLALGTLILIAFFKPWRLRFAKEQRLLLLFYGVSL
GGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACWA
IYILSGQRAGAEHGPATVAIGSLIAALIFVPIGVLQAGEALWHWSVIPLGLAVAILSTALPYSLEMIALTRLPTRTFGTL
MSMEPALAAVSGMIFLGETLTPIQLLALGAIIAASMGSTLTVRKESKIKELDIN

Specific function: Unknown

COG id: COG5006

COG function: function code R; Predicted permease, DMT superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI1787033, Length=295, Percent_Identity=99.3220338983051, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31213; Mature: 31082

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVTALRLALGTLILIAFFK
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PWRLRFAKEQRLLLLFYGVSLGGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPV
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEECEEEEEEEEECCCEEEEHHCCCCCH
DFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACWAIYILSGQRAGAEHGPATVA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHH
IGSLIAALIFVPIGVLQAGEALWHWSVIPLGLAVAILSTALPYSLEMIALTRLPTRTFGT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHH
LMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAASMGSTLTVRKESKIKELDIN
HHHCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
PGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVTALRLALGTLILIAFFK
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PWRLRFAKEQRLLLLFYGVSLGGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPV
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEECEEEEEEEEECCCEEEEHHCCCCCH
DFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACWAIYILSGQRAGAEHGPATVA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHH
IGSLIAALIFVPIGVLQAGEALWHWSVIPLGLAVAILSTALPYSLEMIALTRLPTRTFGT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHH
LMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAASMGSTLTVRKESKIKELDIN
HHHCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]