Click here to switch to the map view.

The map label for this gene is ybhR

Identifier: 170683835

GI number: 170683835

Start: 816698

End: 817804

Strand: Reverse

Name: ybhR

Synonym: EcSMS35_0814

Alternate gene names: 170683835

Gene position: 817804-816698 (Counterclockwise)

Preceding gene: 170679866

Following gene: 170684095

Centisome position: 16.14

GC content: 52.3

Gene sequence:

>1107_bases
ATGTTTCATCGCTTATGGACGTTAATCCGCAAAGAGTTGCAGTCGCTGCTGCGCGAACCGCAAACCCGCGCAATTCTGAT
TTTACCCGTGCTGATTCAGGTGATCCTGTTCCCGTTCGCCGCCACGCTGGAAGTGACCAACGCCACCATCGCCATCTACG
ATGAAGATAACGGCGAGCATTCGGTGGAACTTACTCAACGTTTTGCCCGCGCCAGCGCCTTTACCCATGTGCTGCTGCTG
AAAAGCCCGCAGGAGATCCGCCCGACCATCGACACACAAAAGGCGTTACTCCTGGTGCGTTTCCCGGCTGACTTCTCGCG
CAAACTGGATACCTTCCAGACCGCGCCGTTACAGTTGATCCTAGACGGGCGTAACTCCAACAGTGCGCAAATTGCCGCCA
ACTACCTGCAACAGATCGTCAAAAATTATCAGCAGGAGCTGCTGGAAGGAAAACCGAAACCCAACAACAGCGAGCTGGTG
GTACGCAACTGGTATAACCCGAATCTCGACTACAAATGGTTTGTGGTGCCGTCGCTGATCGCCATGATCACCACTATCGG
CGTAATGATCGTCACGTCACTTTCCGTCGCCCGCGAACGTGAACAAGGTACGCTCGATCAGTTACTGGTTTCGCCGCTCA
CCACCTGGCAGATATTTATCGGCAAAGCCGTACCTGCGTTAATTGTCGCCACGTTTCAGGCCACCATTGTGCTGGCGATT
GGTATCTGGGCGTATCAAATCCCCTTCGCCGGATCGCTGGCGCTGTTCTACTTTACGATGGTGATTTACGGTTTATCGCT
GGTGGGATTCGGTCTGTTGATTTCATCACTCTGTTCAACACAACAACAGGCGTTTATCGGCGTGTTTGTCTTTATGATGC
CCGCCATTCTTCTTTCCGGTTACGTTTCGCCGGTGGAAAACATGCCAGTATGGCTGCAAAACCTGACGTGGATTAACCCT
ATTCGCCACTTTACGGACATTACCAAGCAGATTTATTTGAAGGATGCGAGTCTGGATATTGTGTGGAATAGTTTGTGGCC
GCTACTGGTGATAACGGCCACGACAGGGTCAGCGGCGTACGCGATGTTTAGACGCAAGGTGATGTAA

Upstream 100 bases:

>100_bases
GTACTGGTGGTGAACGTGCTGTTTTTGATCGCTTCGGCGGTGATGTTTATCGGCCTGACGTGGCTGAAAACCAAACGTCG
GCTGGATTAGGGAGAAGAGC

Downstream 100 bases:

>100_bases
TTTTTTATCTTTCGCCAGCAAAGACACTACCGCCGGGCCAGCAAGGATTGCCAGCCCTGCAATTGCCAGCAAAAAGTTGT
TTTCCAGTACACGGGACAAC

Product: ABC-2 type transporter, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLL
KSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAI
GIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINP
IRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM

Sequences:

>Translated_368_residues
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLL
KSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAI
GIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINP
IRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM
>Mature_368_residues
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLL
KSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAI
GIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINP
IRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM

Specific function: Unknown

COG id: COG0842

COG function: function code V; ABC-type multidrug transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain

Homologues:

Organism=Escherichia coli, GI1787010, Length=368, Percent_Identity=100, Blast_Score=746, Evalue=0.0,
Organism=Escherichia coli, GI1787011, Length=335, Percent_Identity=26.5671641791045, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI48994943, Length=354, Percent_Identity=22.5988700564972, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI226510979, Length=374, Percent_Identity=24.331550802139, Blast_Score=108, Evalue=4e-25,
Organism=Drosophila melanogaster, GI85725260, Length=382, Percent_Identity=22.2513089005236, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI85725262, Length=382, Percent_Identity=22.2513089005236, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650853, Length=226, Percent_Identity=24.7787610619469, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650855, Length=226, Percent_Identity=24.7787610619469, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBHR_ECO57 (P0AFQ0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F90737
- RefSeq:   NP_286555.1
- RefSeq:   NP_308897.1
- ProteinModelPortal:   P0AFQ0
- EnsemblBacteria:   EBESCT00000028035
- EnsemblBacteria:   EBESCT00000057798
- GeneID:   917635
- GeneID:   958016
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1012
- KEGG:   ecs:ECs0870
- GeneTree:   EBGT00050000008883
- HOGENOM:   HBG471594
- OMA:   ENMPEWL
- ProtClustDB:   CLSK879768
- BioCyc:   ECOL83334:ECS0870-MONOMER
- InterPro:   IPR000412
- InterPro:   IPR013526
- InterPro:   IPR013525
- PRINTS:   PR00164

Pfam domain/function: PF01061 ABC2_membrane

EC number: NA

Molecular weight: Translated: 41566; Mature: 41566

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x179875bc)-; HASH(0x18016004)-; HASH(0x17173f90)-; HASH(0x18130424)-; HASH(0x17fc316c)-; HASH(0x171d5614)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEH
CHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHEEEECEEEEEEECCCCCH
SVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLI
HHHHHHHHHHHHHHHHHEEECCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEE
LDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELVVRNWYNPNLDYKWFVVPSLI
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEHHHHHH
AMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSPVENMPVWLQNLTWINPIRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAY
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCEEEEEECCCHHHH
AMFRRKVM
HHHHHHCH
>Mature Secondary Structure
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEH
CHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHEEEECEEEEEEECCCCCH
SVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLI
HHHHHHHHHHHHHHHHHEEECCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEE
LDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELVVRNWYNPNLDYKWFVVPSLI
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEHHHHHH
AMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSPVENMPVWLQNLTWINPIRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAY
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCEEEEEECCCHHHH
AMFRRKVM
HHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796