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The map label for this gene is modF [H]

Identifier: 170683734

GI number: 170683734

Start: 784327

End: 785799

Strand: Reverse

Name: modF [H]

Synonym: EcSMS35_0783

Alternate gene names: 170683734

Gene position: 785799-784327 (Counterclockwise)

Preceding gene: 170680486

Following gene: 170683375

Centisome position: 15.5

GC content: 52.27

Gene sequence:

>1473_bases
ATGTCATCGTTGCAAATTTTGCAAGGCACGTTTCGTCTTGGCGACACAAAAACGCTGCAATTGCCTCGGCTAACGTTAAA
CGCGGGTGATAGTTGGGCGTTTGTCGGTTCGAATGGAAGCGGGAAATCGGCGCTGGCCCGCGCGCTGTCGGGGGAACTTC
CGCTTTTGAAAGGTGAACGGCAAAGCCAGTTTTCCCACATCACTCGTCTCTCCTTCGAGCAATTGCAAAAGCTCGTCAGC
GACGAATGGCAGCGGAATAACACCGATATGCTTAGTCCTGGCGAAGATGACACCGGGCGTACCACGGCTGAGATCATTCA
GGATGAAGTAAAGGATACTCCGCGTTGCATGCAACTGGCGCAGCAGTTCGGTATTACCGCCCTCCTCGACCGACGCTTTA
AATACCTTTCCACTGGCGAGACGCGAAAAACCCTGCTGTGTCAGGCGCTGATGTCGGAGCCTGACTTGTTGATTCTTGAT
GAGCCGTTCGATGGCCTGGATGTTGCCTCACGTCAGCAGCTGGCTGAGCTACTCGCCTCGTTACATCAGTCCGGTATTAC
TCTGGTACTGGTGCTCAATCGCTTCGATGAGATCCCAGAATTTGTCCAGTTTGCTGGCGTGCTGGCGGATTGTACGTTAG
CGGAAACTGGCGCTAAAGAGGAACTGCTCCAGCAAGCACTCGTCGCGCAACTGGCACATAGCGAACAGCTTGAAGGTGTG
CAAATGCCGGAGCCGGATGAACCTTCAGCACGTCACGCCTTACCCGCCAACGAACCGCGCATTGTGCTGAACAATGGAGT
GGTTTCTTATAACGAACGCCCCATTCTTAATAACCTTAGCTGGCAGGTGAATCCAGGCGAACACTGGCAAATTGTCGGGC
CAAATGGCGCGGGAAAATCGACGTTATTAAGCCTGATTACTGGCGATCATCCGCAAGGTTACAGCAACGATTTGACGCTT
TTCGGACGACGTCGCGGCAGCGGCGAAACCATCTGGGATATCAAAAAGCATATCGGTTACGTCAGCAGTAGTTTGCATCT
GGATTACCGGGTCAGCACTACTGTGCGTAATGTGATCCTTTCTGGCTATTTTGATTCGATTGGCATTTATCAGGCCGTAT
CGGATCGCCAGCAAAAACTGGTGCAGCAGTGGCTGGATATTCTCGGCATTGATAAACGCACGGCTGACGCTCCTTTCCAT
AGTCTTTCCTGGGGACAGCAGCGTCTGGCGCTGATCGTCCGTGCGCTAGTGAAACATCCGACATTGCTTATTCTCGATGA
ACCACTACAGGGGCTTGATCCGCTCAATCGCCAGCTTATCCGCCGTTTTGTTGATGTGCTGATTAGCGAAGGTGAAACGC
AATTGTTGTTTGTTTCGCACCACGCTGAAGATGCGCCTGCCTGTATTACCCATCGTCTGGAGTTCGTGCCGGACGGTGAC
TTTTATCGCTATGCGCTGACAAAAATAAACTGA

Upstream 100 bases:

>100_bases
GCCGACAGCGTGATTATCGCCACGCTGTGCTAAGCGTGTTGACAATTTGTTATGAAACACGTATCCCTGTCAGTAATCGC
TGCACAAAATGGGATATAAA

Downstream 100 bases:

>100_bases
GTCGGTAGTGCTGACCGTGCCGGAGGCGGCGTAAACGTGTTATCCGGCCAACGGTTTGACGCATGCAGGCATGAAACCGC
GTCTTTTTTTCAGATAAAAA

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSALARALSGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWQRNNTDMLSPGEDDTGRTTAEIIQDEVKDTPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGD
FYRYALTKIN

Sequences:

>Translated_490_residues
MSSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSALARALSGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWQRNNTDMLSPGEDDTGRTTAEIIQDEVKDTPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGD
FYRYALTKIN
>Mature_489_residues
SSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSALARALSGELPLLKGERQSQFSHITRLSFEQLQKLVSD
EWQRNNTDMLSPGEDDTGRTTAEIIQDEVKDTPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDE
PFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGVQ
MPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHS
LSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGDF
YRYALTKIN

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI1786975, Length=489, Percent_Identity=97.5460122699387, Blast_Score=976, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=379, Percent_Identity=27.9683377308707, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788897, Length=517, Percent_Identity=23.0174081237911, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789991, Length=468, Percent_Identity=24.5726495726496, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787041, Length=539, Percent_Identity=22.4489795918367, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI48995001, Length=451, Percent_Identity=23.7250554323725, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788506, Length=485, Percent_Identity=25.5670103092783, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790525, Length=480, Percent_Identity=21.875, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790190, Length=464, Percent_Identity=24.5689655172414, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787792, Length=480, Percent_Identity=23.125, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI2367384, Length=543, Percent_Identity=23.3885819521179, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.0970873786408, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI145693107, Length=496, Percent_Identity=23.3870967741935, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789593, Length=221, Percent_Identity=28.0542986425339, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788225, Length=180, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790544, Length=184, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081782, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=217, Percent_Identity=25.3456221198157, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787112, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=197, Percent_Identity=30.4568527918782, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788472, Length=470, Percent_Identity=21.7021276595745, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082268, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787500, Length=242, Percent_Identity=25.6198347107438, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786803, Length=251, Percent_Identity=24.3027888446215, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788761, Length=219, Percent_Identity=26.9406392694064, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786703, Length=204, Percent_Identity=30.3921568627451, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790739, Length=247, Percent_Identity=27.5303643724696, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=281, Percent_Identity=27.0462633451957, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320266, Length=395, Percent_Identity=29.3670886075949, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24650855, Length=237, Percent_Identity=32.0675105485232, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650853, Length=237, Percent_Identity=32.0675105485232, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362751, Length=237, Percent_Identity=32.0675105485232, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221512771, Length=202, Percent_Identity=26.2376237623762, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574744, Length=196, Percent_Identity=28.0612244897959, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24580930, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85725262, Length=214, Percent_Identity=29.9065420560748, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54629; Mature: 54498

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSALARALSGELPLLKGER
CCCHHHHHHHHCCCCCCEEEECEEEEECCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTTAEIIQDEVKDTPRCMQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGD
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCC
FYRYALTKIN
EEEEEEEECC
>Mature Secondary Structure 
SSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSALARALSGELPLLKGER
CCHHHHHHHHCCCCCCEEEECEEEEECCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTTAEIIQDEVKDTPRCMQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
QMPEPDEPSARHALPANEPRIVLNNGVVSYNERPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGD
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCC
FYRYALTKIN
EEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]