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The map label for this gene is purP [H]

Identifier: 170683636

GI number: 170683636

Start: 4171940

End: 4173277

Strand: Reverse

Name: purP [H]

Synonym: EcSMS35_4081

Alternate gene names: 170683636

Gene position: 4173277-4171940 (Counterclockwise)

Preceding gene: 170682228

Following gene: 170680934

Centisome position: 82.34

GC content: 53.59

Gene sequence:

>1338_bases
ATGAGTCAACAACACACAACCCAGGCTTCTGGCCAGGGGATGCTGGAACGCGTGTTTAAACTGCGCGAACATGGCACGAC
GGCACGGACCGAAGTGATCGCCGGTTTTACCACCTTCCTGACGATGGTTTACATCGTTTTTGTTAACCCGCAAATTCTTG
GCGTTGCTGGCATGGATACCAGCGCCGTCTTCGTCACTACCTGTCTGATTGCTGCATTCGGCAGTATTATGATGGGACTG
TTTGCTAACCTGCCAGTTGCATTGGCACCCGCTATGGGCCTGAATGCGTTCTTCGCTTTTGTGGTTGTGCAGGCGATGGG
CTTGCCGTGGCAAGTCGGGATGGGCGCAATCTTCTGGGGCGCGATTGGTCTACTGTTACTGACGATTTTCCGCGTTCGCT
ACTGGATGATAGCCAACATTCCGGTAAGTCTACGTGTGGGCATCACCAGTGGTATCGGTCTGTTTATTGGCATGATGGGG
CTGAAAAACGCAGGTGTGATTGTCGCTAACCCGGAAACGCTGGTGAGCATCGGTAACCTGACTTCTCACAGCGTGCTGCT
GGGGATCCTCGGCTTCTTCATCATCGCCATTCTGGCCTCGCGCAATATTCACGCGGCGGTGCTGGTTTCCATCGTGGTGA
CAACGCTGCTGGGCTGGATGCTGGGTGATGTCCACTACAACGGCATCGTTTCTGCGCCGCCGAGCGTAATGACTGTCGTG
GGTCATGTAGATTTAGCCGGGTCGTTTAACCTCGGGCTGGCAGGGGTGATTTTCTCTTTCATGCTGGTCAACTTGTTTGA
CTCCTCCGGTACGCTGATTGGCGTGACCGATAAAGCAGGTCTGGCTGATGATAAAGGTAAATTCCCGCGCATGAAGCAGG
CGCTGTATGTCGACAGCATCTCTTCGGTGACCGGTTCGTTTATCGGTACTTCTTCTGTTACGGCGTATATTGAATCTTCT
TCCGGCGTTTCCGTTGGCGGTCGTACCGGTCTGACGGCAGTGGTTGTTGGTCTGCTGTTCCTGCTGGTTATCTTCCTGTC
GCCGCTGGCAGGGATGGTGCCAGGCTACGCTGCAGCTGGTGCGCTGATTTACGTTGGCGTGTTGATGACCTCAAGTCTTG
CTCGCGTGAACTGGCAGGATCTTACTGAATCTGTTCCGGCGTTTATTACCGCTGTGATGATGCCGTTCAGCTTCTCGATT
ACTGAAGGTATCGCGCTGGGCTTTATCTCCTACTGCGTGATGAAGATTGGTACCGGACGTCTGCGTGACCTTAGCCCGTG
CGTAATCATCGTTGCGCTGCTGTTTATCCTGAAGATTGTGTTTATCGACGCTCACTAA

Upstream 100 bases:

>100_bases
TAAGCAAATACAATGAAAAAAAGTTATCTTCAGCCGTCCATATTGTCTCATTTTGGTATACGATAGCGACGGATTTTCCC
TCCTTGTTCGGAAATAGATA

Downstream 100 bases:

>100_bases
AATCGATAGCGCGTTAAAAACCCGCCATGCATGATTGCTGGCGGGTTTTTTATTTAGATCTTAACTCGCTGAATAAACTC
ACCAAATGCGGTCAATTGCC

Product: sulfate permease family inorganic anion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADDKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH

Sequences:

>Translated_445_residues
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADDKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH
>Mature_444_residues
SQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLF
ANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGL
KNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVVG
HVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADDKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSS
GVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSIT
EGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=99.3258426966292, Blast_Score=869, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=444, Percent_Identity=74.0990990990991, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=439, Percent_Identity=35.3075170842825, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=35.8620689655172, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46813; Mature: 46682

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGNL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHEEECCC
TSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHE
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADDKGKFPRMKQALYVDSI
ECEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPGYAAAG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRDLSPCVIIVALLFILKIVFIDAH
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANPETLVSIGNL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHEEECCC
TSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHE
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADDKGKFPRMKQALYVDSI
ECEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPGYAAAG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRDLSPCVIIVALLFILKIVFIDAH
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]