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The map label for this gene is yfdZ [H]

Identifier: 170683338

GI number: 170683338

Start: 2587863

End: 2589101

Strand: Reverse

Name: yfdZ [H]

Synonym: EcSMS35_2531

Alternate gene names: 170683338

Gene position: 2589101-2587863 (Counterclockwise)

Preceding gene: 170679733

Following gene: 170683405

Centisome position: 51.08

GC content: 55.04

Gene sequence:

>1239_bases
ATGGCTGACACTCGCCCTGAACGTCGCTTTACGCGTATTGATCGTCTCCCGCCCTACGTTTTTAATATTACCGCTGAACT
GAAAATGGCTGCGCGTCGGCGCGGCGAAGATATTATCGATTTCAGTATGGGTAACCCGGACGGTGCGACTCCGCCGCATA
TCGTCGAAAAATTATGTACGGTGGCCCAGCGCCCGGACACGCATGGTTACTCCACGTCGCGCGGCATTCCGCGGTTACGT
CGCGCCATTTCCCGCTGGTATCAGGATCGCTACGGCGTTGAGATCGACCCGGAATCAGAAGCTATCGTCACCATTGGTTC
GAAAGAGGGACTGGCGCATCTGATGCTGGCGACGCTGGATCATGGTGACACTGTACTGGTGCCTAATCCAAGCTACCCGA
TTCATATTTACGGCGCGGTGATTGCCGGGGCGCAGGTACGCTCAGTGCCGCTGGTGGAAGGTGTCGATTTCTTCAACGAA
CTGGAACGCGCCATTCGCGAAAGTTATCCGAAACCGAAGATGATGATCCTCGGCTTCCCGTCGAACCCAACCGCGCAATG
CGTGGAGCTGGAATTCTTTGAGAAGGTTGTGGCGCTGGCGAAACGCTACGATGTGCTGGTGGTCCATGACCTGGCCTATG
CCGATATCGTCTACGATGGCTGGAAAGCGCCGTCAATCATGCAGGTGCCAGGTGCACGCGATGTGGCGGTCGAGTTCTTT
ACGCTGTCGAAAAGTTACAACATGGCGGGCTGGCGTATCGGCTTTATGGTCGGTAACAAAACGCTGGTCAGCGCGTTGGC
ACGTATTAAAAGCTATCACGATTACGGCACCTTTACGCCGTTGCAGGTGGCAGCGATTGCGGCGCTGGAGGGCGATCAAC
AGTGCGTGCGCGACATTGCTGAACAGTACAAACGCCGCCGTGATGTACTGGTAAAAGGGCTGCATGAAGCGGGCTGGATG
GTCGAAATGCCGAAGGCTTCGATGTATGTCTGGGCGAAAATCCCGGAACCATATGCGGCCATGGGTTCACTGGAATTTGC
CAAGAAGCTGCTTAACGAAGCGAAGGTCTGTGTCTCTCCAGGGATTGGCTTTGGCGACTACGGCGACACCCATGTTCGCT
TTGCACTGATTGAAAACCGCGATCGTATTCGCCAGGCGATTCGTGGAATTAAAGCGATGTTCCGTGCCGACGGTTTACTA
CCCGCCAGCAGCAAACATATTCACGAAAACGCGGAATAA

Upstream 100 bases:

>100_bases
CGCTGGACAGACAGAAATTAATCAGGCTATTTTCAAAACAGCCACCATCGTGGCAGCGTCGCTCGGACGGTCCGGGCGCT
AACGTTAATCTGAGGAAATT

Downstream 100 bases:

>100_bases
ACACCATCGCCAGAAATGCAAACAGGAGCCAGATGGCTCCTGTTTTTCATTGCACAGTTTGCTTTTAGATCATCAGGGCA
AAAGTACCGGCCCAAACGAT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISRWYQDRYGVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLL
PASSKHIHENAE

Sequences:

>Translated_412_residues
MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISRWYQDRYGVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLL
PASSKHIHENAE
>Mature_411_residues
ADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRR
AISRWYQDRYGVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNEL
ERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFFT
LSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMV
EMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLLP
ASSKHIHENAE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=421, Percent_Identity=25.41567695962, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI56713256, Length=421, Percent_Identity=25.41567695962, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI95147551, Length=417, Percent_Identity=22.7817745803357, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI169881279, Length=417, Percent_Identity=22.7817745803357, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=21.6101694915254, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788722, Length=412, Percent_Identity=99.7572815533981, Blast_Score=850, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=337, Percent_Identity=25.5192878338279, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788627, Length=376, Percent_Identity=26.063829787234, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787710, Length=312, Percent_Identity=26.6025641025641, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788332, Length=269, Percent_Identity=27.1375464684015, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=24.3718592964824, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=365, Percent_Identity=24.3835616438356, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=367, Percent_Identity=24.5231607629428, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=24.2857142857143, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=21.1195928753181, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28573069, Length=340, Percent_Identity=27.3529411764706, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24646114, Length=340, Percent_Identity=27.3529411764706, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573067, Length=340, Percent_Identity=27.3529411764706, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573065, Length=340, Percent_Identity=27.3529411764706, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24641770, Length=387, Percent_Identity=25.3229974160207, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641760, Length=387, Percent_Identity=25.3229974160207, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641768, Length=387, Percent_Identity=25.3229974160207, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641766, Length=387, Percent_Identity=25.3229974160207, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641764, Length=387, Percent_Identity=25.3229974160207, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551451, Length=387, Percent_Identity=25.3229974160207, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 46159; Mature: 46028

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCT
CCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQRPDTHGYSTSRGIPRLRRAISRWYQDRYGVEIDPESEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
CCCCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCHHEEEEE
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCEEECC
GIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLLPASSKHIHENAE
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCT
CCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQRPDTHGYSTSRGIPRLRRAISRWYQDRYGVEIDPESEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
CCCCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCHHEEEEE
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCEEECC
GIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLLPASSKHIHENAE
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]