Click here to switch to the map view.

The map label for this gene is visC [H]

Identifier: 170683096

GI number: 170683096

Start: 3128893

End: 3130095

Strand: Reverse

Name: visC [H]

Synonym: EcSMS35_3040

Alternate gene names: 170683096

Gene position: 3130095-3128893 (Counterclockwise)

Preceding gene: 170680909

Following gene: 170683999

Centisome position: 61.76

GC content: 55.2

Gene sequence:

>1203_bases
ATGCAAAGTGTTGATGTAGCCATTGTTGGTGGCGGCATGGTGGGGCTGGCGGTTGCCTGCGGCTTACAGGGGAGCGGCTT
ACGCGTTGCCGTACTGGAGCAGCGCGTACCGGAACCTCTGGCGGCGGATGCACCACCACAACTGCGCGTTTCGGCTATCA
ATGCCGCCAGCGAAAAATTACTCACCCGTCTTGGCGTCTGGCAGGACATTCTCTCTCGTAGGGCCAGCTGTTATCACGGC
ATGGAAGTGTGGGATAAAGACAGCTTTGGTCACATTTCGTTTGACGATCAAAGCATGGGCTATAGCCATCTTGGGCATAT
CGTTGAAAATTCAGTGATTCACTACGCGCTGTGGAACAAAGCGCAGCAGTCGTCAGATATCACTCTGTTGGCCCCCGCAG
AATTACAGCAGGTCGCCTGGGGAGAAAATGAAACCTTCCTGACGCTGAAAGATGGCAGCATGTTAACGGCGCGTCTGGTG
ATTGGCGCGGACGGCGCTAATTCCTGGTTGCGCAACAAAGCCGATATTCCGCTGACTTTCTGGGATTATCAGCATCACGC
GCTGGTAGCGACCATTCGCACGGAAGAACCGCATGATGCGGTGGCGCGGCAGGTTTTCCATGGCGAAGGCATTCTGGCCT
TTTTACCGCTTAGCGATCCGCATCTTTGCTCGATTGTCTGGTCACTGTCGCCAGAGGAAGCGCAGCGGATGCAGCAGGCA
AGTGAAGACGAATTTAATCGCGCGTTAAATATCGCTTTTGATAATCGCCTGGGCTTATGCAAGGTTGAGAGCGCGCGTCA
GGTGTTCCCACTGACGGGGCGTTATGCGCGCCAGTTTGCCGCGCACCGTCTGGCGTTGGTGGGCGACGCCGCACATACCA
TTCACCCGCTCGCGGGGCAGGGCGTTAATCTCGGCTTTATGGATGCTGCAGAGCTGGTTGCTGAACTGAAACGGTTGCAT
CGTCAGGGGAAAGACATCGGGCAGTACATTTATCTGCGTCGCTATGAGCGTAGCCGCAAGCACAGTGCGGCGCTGATGCT
GGCTGGTATGCAGGGATTCCGCGATCTGTTTTCCGGTACCAATCCGGCGAAAAAACTGCTGCGTGATATTGGTTTGAAAC
TGGCCGACACGCTTCCTGGCGTTAAACCACAACTTATCCGCCAGGCAATGGGATTAAACGATTTGCCTGAATGGCTGCGT
TAA

Upstream 100 bases:

>100_bases
GGGCTGATGACGATGGAATTATTTACCCCGGCACGCGATGTGCTGGCGCAGCGCACCCTCGGTTGGGTGGCGCGTTGAAG
GCGGTTTTAAGGAATAAACA

Downstream 100 bases:

>100_bases
AAATTTCTCTTCTGCTGTTTATTTGATACCCATCACACTTTCATCTCCCGTTTTTTTCGCCGGGAGATTTTCCTCATTTG
AAATAAACTAATTTCACCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELVAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR

Sequences:

>Translated_400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELVAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
>Mature_400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELVAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=381, Percent_Identity=34.3832020997375, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI32967307, Length=348, Percent_Identity=34.4827586206897, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1789273, Length=400, Percent_Identity=98.75, Blast_Score=813, Evalue=0.0,
Organism=Escherichia coli, GI1786883, Length=392, Percent_Identity=39.030612244898, Blast_Score=250, Evalue=9e-68,
Organism=Escherichia coli, GI1789274, Length=393, Percent_Identity=30.5343511450382, Blast_Score=168, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI25146631, Length=431, Percent_Identity=32.2505800464037, Blast_Score=181, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6321694, Length=458, Percent_Identity=25.1091703056769, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI19920760, Length=384, Percent_Identity=34.375, Blast_Score=182, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44176; Mature: 44176

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKL
CCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEHHHCC
AQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
CCCCCCEEEECHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCHHHCCCCCCCEEE
WDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
ECCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHC
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQ
CHHHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCC
GVNLGFMDAAELVAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGT
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
CHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCCCHHHHC
>Mature Secondary Structure
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKL
CCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEHHHCC
AQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
CCCCCCEEEECHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCHHHCCCCCCCEEE
WDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
ECCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHC
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQ
CHHHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCC
GVNLGFMDAAELVAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGT
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
CHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCCCHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]