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The map label for this gene is frvR [H]

Identifier: 170683057

GI number: 170683057

Start: 4389292

End: 4391040

Strand: Reverse

Name: frvR [H]

Synonym: EcSMS35_4287

Alternate gene names: 170683057

Gene position: 4391040-4389292 (Counterclockwise)

Preceding gene: 170683436

Following gene: 170680923

Centisome position: 86.64

GC content: 49.86

Gene sequence:

>1749_bases
ATGCTAAACGAACGCCAGTTAAAGATTGTCGATCTGCTGGAGCAACAGCCACGCACGCCTGGCGAGCTGGCGCAACAGAC
TGGCGTTTCCGGCAGGACCATCCTGCGTGATATTGACTATCTCAACTTTACCCTTAACGGCAAAGCCCGCATTTCCGCCA
GTGGCAACGCGGGCTATCAGCTGGAAATCTTCGAGCGCCGCAGCTTTTTTCAGTTGCTGCAAAAGCACGATAACGACGAT
CGGCTGCTGGCGCTGTTATTACTGAATACCTTCACTCCCCGTGCGCAACTCGCCTCGGCGCTTAATTTGCCAGAAACGTG
GGTAGCAGAGCGCCTGCCCCGCCTGAAACAGCGCTATGAACGCGGTTTTTGTCTCGCTAGTCGCCCTGGTTTGGGCCATT
TCATTGATGAGACAGAAGAGAAACGCATTATTTTGCTGGCGAATCTTTTACGCAAAGATCCGTTTTTAATTCCGCTGTCG
GGCGTAACACGAGACAATTTTCAACAATTAACCACCGCCTGCGAAAAGCAACGTCGCTGGCCGCTGATGCAAGGCGACTA
TCTCTCAAGCCTGATTCTGGCGATTTACGCCCTGCGTAATCAACTGACCGATGAGTGGCCGCAATATCCCGGTGACGAGA
TAAAACAAATCGTTGAACAGAGCGGCCTGTTTCTTGGTGATAACGCTGTAAGAACCCTGACAGGTTTGATAGAGAAACAG
CATCAGCAAGCGCAGGTAATTTCTGCCGATCATGTGCTGGGGTTGCTGCAAAGGGTGCCAGGCATCGCGTCATTGAATAT
TATTGATACGCAGTTGGTTGAGAATATTACCGGGCATTTATTACGTTGCCTTGCCGCACCGGTGTGGATTGCCGAGCACC
GCCAAAGCAGCATGAATAACCTGAAAGCCGCCTGGCCTGCGGCCTTTGATATGAGTCTGCACTTTATTACGCTACTGCGT
GAACAGCTCGATATTCCCCTTTTCGACAGCGATCTGATCGGTTTGTATTTTGCCTGTGCGCTGGAACGGCATCAAAACGA
ACGCCAGCCGATCATTTTGCTCTCGGACCAGAACGCGATTGCCACCATTAATCAGCTCGCCATTGAGCGCGATGTTTTAC
ATTGTCGGGTGATTATTGCCCGTAGCTTAAGCGAACTTGTTGCCATTCGCGAAGAGATTGAGCCGTTATTGATCATTAAC
AACAGCCATTATTTACTGGATGACGCGGTAAATAATTACATCACCGTAAAAAATATCATTACGGCTGCCGGTATCGAACA
AATAAAACATTTTCTGGCGACGGCATTTATTCGCCAGCAACCGGAGCGTTTTTTCTCTGCCCCCGGAAGTTTTCATTATT
CGAATGTACGCGGTGAAAGCTGGCAACATATTACCCGGCAAATTTGTGCTCAATTAGTCGCACAACACCATATTACCGCC
GATGAAGCGCAACGGATCATCGCCCGCGAAGGCGAAGGTGAAAACCTGATTGTTAATCGCCTCGCCATCCCACATTGCTG
GAGCGAACAGGAGCGACGTTTTCGTGGATTTTTTATTACCCTCGCCCAACCGGTTGAGGTGAATAACGAAGTAGTTAACC
ATGTACTGATCGCCTGTGCCGCCGCCGATGCGCGTCATGAGCTAAAAATATTTAGCTATCTGGCAAGCGTATTGTGCCAG
CATCCGGCAGAGGTTATTGCCGGGTTAACAGGATATGAGGCATTTATGGAGTTACTTCACAAGGGGTGA

Upstream 100 bases:

>100_bases
AAGCCGATTACGATGCTCTGCTCACGTTGATAAGGGATTTTCTGACCACCTTAACCGCGGAGAAAGTCAACGCGTTTAGC
CAGTTCCGTCAGGTGGATTA

Downstream 100 bases:

>100_bases
ACTGTGTCGGATGCGCCGCATCCGACACTGCATTTATCACCAAAATCAAAAACGTTTAACGCAAGCTATTATAGTCATCG
ACCATTTCGTTGTACTCGCG

Product: putative frv operon regulatory protein

Products: NA

Alternate protein names: Putative phosphotransferase EIIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARISASGNAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERGFCLASRPGLGHFIDETEEKRIILLANLLRKDPFLIPLS
GVTRDNFQQLTTACEKQRRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGLFLGDNAVRTLTGLIEKQ
HQQAQVISADHVLGLLQRVPGIASLNIIDTQLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLHCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVVNHVLIACAAADARHELKIFSYLASVLCQ
HPAEVIAGLTGYEAFMELLHKG

Sequences:

>Translated_582_residues
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARISASGNAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERGFCLASRPGLGHFIDETEEKRIILLANLLRKDPFLIPLS
GVTRDNFQQLTTACEKQRRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGLFLGDNAVRTLTGLIEKQ
HQQAQVISADHVLGLLQRVPGIASLNIIDTQLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLHCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVVNHVLIACAAADARHELKIFSYLASVLCQ
HPAEVIAGLTGYEAFMELLHKG
>Mature_582_residues
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARISASGNAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERGFCLASRPGLGHFIDETEEKRIILLANLLRKDPFLIPLS
GVTRDNFQQLTTACEKQRRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGLFLGDNAVRTLTGLIEKQ
HQQAQVISADHVLGLLQRVPGIASLNIIDTQLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLHCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVVNHVLIACAAADARHELKIFSYLASVLCQ
HPAEVIAGLTGYEAFMELLHKG

Specific function: Could be involved in the regulation of the transcription of the FRV operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790331, Length=582, Percent_Identity=96.3917525773196, Blast_Score=1137, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF00359 PTS_EIIA_2 [H]

EC number: NA

Molecular weight: Translated: 66080; Mature: 66080

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARISASGNAGYQ
CCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHCCEEEEEECCCEEEEECCCCCEE
LEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYE
EEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
RGFCLASRPGLGHFIDETEEKRIILLANLLRKDPFLIPLSGVTRDNFQQLTTACEKQRRW
CCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCC
PLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGLFLGDNAVRTLTGLIEKQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHH
HQQAQVISADHVLGLLQRVPGIASLNIIDTQLVENITGHLLRCLAAPVWIAEHRQSSMNN
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAI
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
ATINQLAIERDVLHCRVIIARSLSELVAIREEIEPLLIINNSHYLLDDAVNNYITVKNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHCCEEEHHHHH
TAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCH
DEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVVNHVLIACA
HHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH
AADARHELKIFSYLASVLCQHPAEVIAGLTGYEAFMELLHKG
HHCCHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARISASGNAGYQ
CCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHCCEEEEEECCCEEEEECCCCCEE
LEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYE
EEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
RGFCLASRPGLGHFIDETEEKRIILLANLLRKDPFLIPLSGVTRDNFQQLTTACEKQRRW
CCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCC
PLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEQSGLFLGDNAVRTLTGLIEKQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHH
HQQAQVISADHVLGLLQRVPGIASLNIIDTQLVENITGHLLRCLAAPVWIAEHRQSSMNN
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAI
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
ATINQLAIERDVLHCRVIIARSLSELVAIREEIEPLLIINNSHYLLDDAVNNYITVKNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHCCEEEHHHHH
TAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCH
DEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVVNHVLIACA
HHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH
AADARHELKIFSYLASVLCQHPAEVIAGLTGYEAFMELLHKG
HHCCHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8019415 [H]