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The map label for this gene is cfaB [H]

Identifier: 170683018

GI number: 170683018

Start: 3475178

End: 3475678

Strand: Reverse

Name: cfaB [H]

Synonym: EcSMS35_3388

Alternate gene names: 170683018

Gene position: 3475678-3475178 (Counterclockwise)

Preceding gene: 170681823

Following gene: 170682266

Centisome position: 68.58

GC content: 46.31

Gene sequence:

>501_bases
ATGAAAAAGGTATTCGCAAAATCTCTTCTGGTAGCGGCAATGTTTTCCGTTGCAGGTTCTGCATTAGCAGTACAAAAAGA
TATCACTGTTACTGCTAACGTTGATGCTGCTCTGGATATGACGCAGACCGATAATACTGCACTGCCGAAGGCAGTAGAAA
TGCAATATCTGCCAGGTCAGGGTCTGCAATCTTACCAGTTAATGACTAAAATCTGGTCAAATGACACGACCAAAGACGTG
AAAATGCAGTTAGTTTCGCCTGCGCAACTGGTTCAGAGCCTGGACGCCAGCAAAATTGTTCCGCTGACCGTAACCTGGGG
TGGTGAAGAGATTAAAGCTGATGCGGCAACCACTTTTACCGCAACGAAAATCTTTGCTTCCGATGCGTTAACTAACGGTT
CGCTGGCTAAACCACTGATGTTTTCCCAGGCTACCAAAGGTGTTCTGGAAACGGGTATCTACCGTGGCGTAGTTAGCATT
TATCTGTCCCAGGCTCTCTAA

Upstream 100 bases:

>100_bases
ATAAAATCGTTGTCAAATATAATAACTGGATCACCAAGGACAATGGCGAGTTTGAGCTGGCGGTCCATTAATTATCATTG
TAATAAACCAAGGAATAGTA

Downstream 100 bases:

>100_bases
TCTGGATAACAGAATTAACATGCAATAAAGGGAGGCAAGTCCTCCCTTCTTTTAACTATTTTAGTATTTATTATGGATTA
CAGGACAGCCATGGACAAAA

Product: CS1 type fimbrial major subunit

Products: NA

Alternate protein names: CFA/I antigen; CFA/I pilin; Colonization factor antigen I subunit B [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTDNTALPKAVEMQYLPGQGLQSYQLMTKIWSNDTTKDV
KMQLVSPAQLVQSLDASKIVPLTVTWGGEEIKADAATTFTATKIFASDALTNGSLAKPLMFSQATKGVLETGIYRGVVSI
YLSQAL

Sequences:

>Translated_166_residues
MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTDNTALPKAVEMQYLPGQGLQSYQLMTKIWSNDTTKDV
KMQLVSPAQLVQSLDASKIVPLTVTWGGEEIKADAATTFTATKIFASDALTNGSLAKPLMFSQATKGVLETGIYRGVVSI
YLSQAL
>Mature_166_residues
MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTDNTALPKAVEMQYLPGQGLQSYQLMTKIWSNDTTKDV
KMQLVSPAQLVQSLDASKIVPLTVTWGGEEIKADAATTFTATKIFASDALTNGSLAKPLMFSQATKGVLETGIYRGVVSI
YLSQAL

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial CS1 protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007540 [H]

Pfam domain/function: PF04449 Fimbrial_CS1 [H]

EC number: NA

Molecular weight: Translated: 17668; Mature: 17668

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTDNTALPKAVEMQYLPGQ
CCHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCEEECCCCCCCCCCCCEEEEECCCC
GLQSYQLMTKIWSNDTTKDVKMQLVSPAQLVQSLDASKIVPLTVTWGGEEIKADAATTFT
CCHHHHHHHHHHCCCCCCHHHEEECCHHHHHHHCCCCCEEEEEEEECCCEEECCCHHHHH
ATKIFASDALTNGSLAKPLMFSQATKGVLETGIYRGVVSIYLSQAL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTDNTALPKAVEMQYLPGQ
CCHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCEEECCCCCCCCCCCCEEEEECCCC
GLQSYQLMTKIWSNDTTKDVKMQLVSPAQLVQSLDASKIVPLTVTWGGEEIKADAATTFT
CCHHHHHHHHHHCCCCCCHHHEEECCHHHHHHHCCCCCEEEEEEEECCCEEECCCHHHHH
ATKIFASDALTNGSLAKPLMFSQATKGVLETGIYRGVVSIYLSQAL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2564374; 2569152; 6124420; 2572583 [H]