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The map label for this gene is ylaB [H]

Identifier: 170682326

GI number: 170682326

Start: 505380

End: 506930

Strand: Reverse

Name: ylaB [H]

Synonym: EcSMS35_0500

Alternate gene names: 170682326

Gene position: 506930-505380 (Counterclockwise)

Preceding gene: 170684122

Following gene: 170682578

Centisome position: 10.0

GC content: 47.84

Gene sequence:

>1551_bases
GTGAGAACACGACATCTGGTCGGCCTTATTTCGGGAGTACTGATTCTTTCAGTATTGCTGCCTGTCGGCTTAAGCATCTG
GCTGGCCCATCAGCAGGTAGAAACATCATTTATTGAAGAGCTGAATACGTATTCCTCCCGCGTCGCTATTCGGGCCAATA
AGGTGGCGACACAAGGGAAAGATGCGCTGCAAGAGCTGGAAAGATGGCAAGGCGCTGCCTGTAGCGAAGCCCATCTCATG
GAAATGCGTCGGGTATCTTACAGTTATCGCTATATTCAGGAAGTGGTTTATATCGATAACAACGTTCCCCAGTGTTCGTC
TCTGGAGCATGAAAGCCCGCCCGATACCTTCCCCGAGCCAGGTAAAATTTCGAAAGATGGTTATCGTGTCTGGTTAACAT
CGCATAACGATTTAGGCATTATCCGTTACATGGTCGCCATGGGAACGGCACATTATGTCGTCATGATCGACCCCGCTTCC
TTTATTGATGTCATTCCCTATAGCTCATGGCAAATTGATGCCGCCATTATTGGCAATGCCCATAACGTTGTGATAACCAG
CAGTGATGAAATTGCTCAGGGAATTATTACCAGACTACAAAAAACACCCGGTGAGCATATCGAAAATAATGGAATCATTT
ACGATATCCTGCCCTTACCGGAGATGAATATTTCGATCATCACCTGGGCTTCAACGAAAATGTTGCAGAAAGGCTGGCAT
CGGCAAGTCTTTATTTGGTTACCGTTCGGGTTGGTGATTGGCCTGCTGGCAGCGATGTTTGTGCTGCGTATTTTGCGCCG
TATCCAGTCACCGCATCATCGGCTGCAGGATGCTATCGAAAATCGTGATATTTGCGTGCACTATCAGCCGATTGTCTCCT
TAGCCAATGGCAAAATTGTCGGTGCTGAGGCACTGGCGCGCTGGCCGCAGACAGACGGTAGTTGGTTGTCACCAGATAGT
TTTATTCCGCTGGCACAGCAAACGGGGCTTTCTGAGCCGTTGACGCTACTGATTATAAAAAGTGTCTTTGAAGATATGGG
CGACTGGCTGCGTCAGCATCCGCAGCAGCATATTTCGATCAATCTTGAATCCACCGTGCTCACCTCGGAAAAAATCCCGC
AATTGCTGCGTGAAATGATCAATCACTATCAGGTTAATCCCAGACAGATCGCGCTTGAACTCACTGAACGCGAGTTTGCC
GATCCGAAAACCAGCGCCCCGATAATTTCTCGCTACCGGGAGGCGGGCCATGAAATTTATCTCGATGATTTTGGTACGGG
GTATTCAAGTTTAAGCTATTTACAGGATCTGGATGTCGACATTCTGAAGATCGATAAATCTTTCGTTGATGCGCTGGAAT
ATAAAAATGTCACGCCACATATCATCGAAATGGCAAAAACACTGAAACTGAAAATGGTAGCGGAGGGAATCGAAACCAGT
AAACAAGAAGAGTGGCTACGTCAGCATAGCGTGCACTACGGCCAGGGCTGGCTCTACAGCAAGGCATTACCGAAAGAGGA
TTTCTTACGCTGGGCCGAGCAACATTTGTGA

Upstream 100 bases:

>100_bases
CATCACTTCATGAAATCCCGGCTCTACCTCCTTATCTCCTGCCAGCCTTTTTCCACAATCAGATATACTTTCCCTACACT
GTGTTAATAAGGATATGCTG

Downstream 100 bases:

>100_bases
ATTTTAGGGCTGACGGCACGCCGCACAGCCCGTCCGCTACCTACTCGTCGATGATTGATTCGAATCCACCATAGATCATT
CGCTTGCCGTCAAACGGCAT

Product: cyclic diguanylate phosphodiesterase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTYSSRVAIRANKVATQGKDALQELERWQGAACSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKGWH
RQVFIWLPFGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIKSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHSVHYGQGWLYSKALPKEDFLRWAEQHL

Sequences:

>Translated_516_residues
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTYSSRVAIRANKVATQGKDALQELERWQGAACSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKGWH
RQVFIWLPFGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIKSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHSVHYGQGWLYSKALPKEDFLRWAEQHL
>Mature_516_residues
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTYSSRVAIRANKVATQGKDALQELERWQGAACSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKGWH
RQVFIWLPFGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIKSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHSVHYGQGWLYSKALPKEDFLRWAEQHL

Specific function: Unknown

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=98.6434108527132, Blast_Score=1049, Evalue=0.0,
Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=33.5227272727273, Blast_Score=298, Evalue=8e-82,
Organism=Escherichia coli, GI87081845, Length=293, Percent_Identity=34.4709897610922, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI226510982, Length=237, Percent_Identity=35.4430379746835, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1788502, Length=270, Percent_Identity=31.1111111111111, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=29.9595141700405, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87081980, Length=236, Percent_Identity=36.0169491525424, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=32.3651452282158, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=33.469387755102, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788849, Length=263, Percent_Identity=30.0380228136882, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082096, Length=246, Percent_Identity=30.4878048780488, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=26.9709543568465, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58802; Mature: 58802

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTYSSRVAIRANKVATQGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHCCH
DALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIGNA
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCC
HNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKGWH
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEECHHHHHHCCCC
RQVFIWLPFGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIV
CEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCCEE
GAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIKSVFEDMGDWLRQHPQQHISI
CHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEE
NLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHEIY
EEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCEEE
LDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
EECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KQEEWLRQHSVHYGQGWLYSKALPKEDFLRWAEQHL
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTYSSRVAIRANKVATQGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHCCH
DALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIGNA
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCC
HNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKGWH
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEECHHHHHHCCCC
RQVFIWLPFGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIV
CEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCCEE
GAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIKSVFEDMGDWLRQHPQQHISI
CHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEE
NLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHEIY
EEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCEEE
LDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
EECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KQEEWLRQHSVHYGQGWLYSKALPKEDFLRWAEQHL
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]