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The map label for this gene is dgoK_1 [H]

Identifier: 170682158

GI number: 170682158

Start: 4150361

End: 4151239

Strand: Reverse

Name: dgoK_1 [H]

Synonym: EcSMS35_4059

Alternate gene names: 170682158

Gene position: 4151239-4150361 (Counterclockwise)

Preceding gene: 170682667

Following gene: 170681080

Centisome position: 81.9

GC content: 53.81

Gene sequence:

>879_bases
ATGACAGCTCGCTACATCGCAATTGACTGGGGATCGACCAATCTGCGCGCCTGGCTTTATCAGGGCGACCACTGCCTGGA
CAGCAGGCAATCAGAAGCAGGTGTCACGCGTCTGAACGGAAAATCTCCAGCTGCGGTGCTAGCGGAAGTGACGACCGACT
GGCGTGAAGAGAATACGCCAGTGGTGATGGCAGGAATGGTCGGCAGCAATGTCGGCTGGAAAGTTGCGCCGTATTTATCT
GTTCCTGCCCGTTTTTCATCTATTGGCGAACAATTAACGTCTGTTGGCGACAATATCTGGATTATTCCCGGATTATGCAT
CTCTCATGACGATAACCACAATGTGATGCGCGGCGAAGAAACACAATTGATCGGCGCGCGCACTTTGGCTCCTTCCTCTC
TTTATGTTATGCCCGGAACCCATTGCAAATGGGTGCAGGCCGATAGCCAGCAAATCAACGATTTTCGCACCGTAATGACC
GGTGAATTACATCATTTACTGTTAAATCACTCATTGATTGGCGCAGGTTTGCCGCCGCAGGAAAACTCTGCCGATGCCTT
CGCGGCTGGCCTTGAGCGTGGCCTTAATGCGCCCGCCATATTGCCGCAGCTTTTTGAAGTTCGCGCCTCGCATGTGCTGG
GAACACTTCTCCGCGAACAGGTCAGTGAATTTCTCTCTGGTTTGTTGATTGGCGCAGAGGTTGCCAGTATGCGCGACTAT
GTGACCCATCAACACGCCATCACCCTTGTCGCCGGAACATCGCTGACCGCGCGCTACCAGCAAGCCTTTCAAGCGATGGG
TTGCGACGTGGCGGCGGTAGCGGGCGACACGGCATTTCAGGCTGGTATAAGGAGCATCGCTCATGCAGTGGCAAACTAA

Upstream 100 bases:

>100_bases
AGGCGCTGTTTGATGCGATACGGCATCAGGACGGCGATGCGGCAGAGCAGGCGGCGCTTACCATGATCGCCAGCTCGACA
CGAAGGTTAAAGGAAATCAC

Downstream 100 bases:

>100_bases
ACTCCCGCTGATCGCCATTTTGCGCGGCATTACGCCCGACGAGGCGCTGGCGCATGTTGGCGCGGTGATTGACGCCGGGT
TCGACGCGGTTGAAATCCCG

Product: 2-dehydro-3-deoxygalactonokinase

Products: NA

Alternate protein names: 2-keto-3-deoxy-galactonokinase; 2-oxo-3-deoxygalactonate kinase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPAAVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLS
VPARFSSIGEQLTSVGDNIWIIPGLCISHDDNHNVMRGEETQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
GELHHLLLNHSLIGAGLPPQENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLLREQVSEFLSGLLIGAEVASMRDY
VTHQHAITLVAGTSLTARYQQAFQAMGCDVAAVAGDTAFQAGIRSIAHAVAN

Sequences:

>Translated_292_residues
MTARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPAAVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLS
VPARFSSIGEQLTSVGDNIWIIPGLCISHDDNHNVMRGEETQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
GELHHLLLNHSLIGAGLPPQENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLLREQVSEFLSGLLIGAEVASMRDY
VTHQHAITLVAGTSLTARYQQAFQAMGCDVAAVAGDTAFQAGIRSIAHAVAN
>Mature_291_residues
TARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPAAVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLSV
PARFSSIGEQLTSVGDNIWIIPGLCISHDDNHNVMRGEETQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMTG
ELHHLLLNHSLIGAGLPPQENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLLREQVSEFLSGLLIGAEVASMRDYV
THQHAITLVAGTSLTARYQQAFQAMGCDVAAVAGDTAFQAGIRSIAHAVAN

Specific function: D-galactonate degradation; second step. [C]

COG id: COG3734

COG function: function code G; 2-keto-3-deoxy-galactonokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790128, Length=292, Percent_Identity=96.5753424657534, Blast_Score=558, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007729 [H]

Pfam domain/function: PF05035 DGOK [H]

EC number: =2.7.1.58 [H]

Molecular weight: Translated: 31399; Mature: 31268

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPAAVLAEVTTDWREENTP
CCCEEEEEEECCCCEEEEEEECCHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCC
VVMAGMVGSNVGWKVAPYLSVPARFSSIGEQLTSVGDNIWIIPGLCISHDDNHNVMRGEE
EEEEEEECCCCCCEEECCEECCHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCCCC
TQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMTGELHHLLLNHSLIGAGLPPQ
CEEEEEEECCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCC
ENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLLREQVSEFLSGLLIGAEVASMRDY
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHQHAITLVAGTSLTARYQQAFQAMGCDVAAVAGDTAFQAGIRSIAHAVAN
HHHHHEEEEEECCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPAAVLAEVTTDWREENTP
CCEEEEEEECCCCEEEEEEECCHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCC
VVMAGMVGSNVGWKVAPYLSVPARFSSIGEQLTSVGDNIWIIPGLCISHDDNHNVMRGEE
EEEEEEECCCCCCEEECCEECCHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCCCC
TQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMTGELHHLLLNHSLIGAGLPPQ
CEEEEEEECCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCC
ENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLLREQVSEFLSGLLIGAEVASMRDY
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHQHAITLVAGTSLTARYQQAFQAMGCDVAAVAGDTAFQAGIRSIAHAVAN
HHHHHEEEEEECCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]