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The map label for this gene is yadA [H]

Identifier: 170681895

GI number: 170681895

Start: 3270859

End: 3271968

Strand: Reverse

Name: yadA [H]

Synonym: EcSMS35_3187

Alternate gene names: 170681895

Gene position: 3271968-3270859 (Counterclockwise)

Preceding gene: 170680378

Following gene: 170683655

Centisome position: 64.56

GC content: 49.46

Gene sequence:

>1110_bases
ATGCTTAAAAGACGTGATGCTTTTTTAAAGAAAAGCGCGCTGGCAGTGAGTGTGGCCCTGCTGCTCTCATCTCAGGCTTC
GGCTAATAAATCAATTACTGATTCAACGGCGGGTATTATCTGGATTGATGGTGGCGGTCAGTCACTTGAAAAAGTAGCTG
TGATTGACCGTCAACTAAATGATACAGGATATAATTTTGCCGTAGGTAGTGGTGCAGCAATTCTGGATGCGGATAAATCC
ATGGCAGTGGGAAATAATACAGCTGTTTTTAATGCAGACAACAGTGTCGCTCTGGGGTATGGCTCTCAGGTGAATGGAGA
AAGCAATGTACTTTCTGTAGGGGCCGGTCCTTCAGGATATGGATTTTCAGTTGATGGTGCACCGGAAACCCGCCGGATTA
TAAATGTTTCAGATGGTGTTAAGGATAGTGATGCGGCCACAAAAGGACAGATGGACAACGCCATTGCAGATGCTGTACGG
GAGTCGGGGGATGCCCTGCGCGGTGAGATAGGAGCTGTCTACCGTGATGCTGTTGCTGATGCTAAGAGTCGAGTGGAATC
GGCAGAAAACAGACTTAACGGTAATATTACAGCTGCCAGGGCTTCTGCGCAGGAATACACGGATGCGGTGAAGTCGGATG
TTCTGGACGAGACGCGTACATATACAGACAGCAGTGTGCGTACTGTCCGTAACGAGGTGAAAAGCCAGGCAGAACATCTC
AGCGATGTGCTTGTGAAGAACAGGGCGCAGACGGATGCAGCAATAGCCTCAAATACAGCAGCGATAAGGAATAACAGTCA
TCGTCTGGATTTGACGGAAGCCTGGCAGAAGATGGCGACAGAGAGAATGAATAATATGCAGGAGCAGATTAAAGAGAACC
GGAAGGAGTTAAGGGAGAGTGCAGCCCAGAGCGCGGCACTGGCAGGTCTTTTCCAGCCATACAGTGTTGGAAAATTTAAC
GCGACAGCAGCCGTTGGTGGTTACCGTGATGAGCAGGCCATTGCGGTGGGCGTGGGCTACCGTTTCACAGAGAATGTGGC
AGGAAAAGTTGCAGTTGCTGCAGGTGGGTCATCCGCATCGTGGAATGCTGGTGTGAATTTTGAGTTCTGA

Upstream 100 bases:

>100_bases
CCTGGTATTATTAAATTAATAAAAGAGGATTCTTATCACTGTATTTTTGCTCCGCACTACCGTTCTGGCTGGTGAAGTAA
TAATACAGGAGAATAACAGA

Downstream 100 bases:

>100_bases
CAGGTCAGGATTTAGATATCTGTCCCGGGGGAAGTCCCCCGGGATATAATGAGGTACAGAGATGCTGGATATAATCCTGG
CGACGAGAGATATTTATTTT

Product: putative immunoglobuling-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLKRRDAFLKKSALAVSVALLLSSQASANKSITDSTAGIIWIDGGGQSLEKVAVIDRQLNDTGYNFAVGSGAAILDADKS
MAVGNNTAVFNADNSVALGYGSQVNGESNVLSVGAGPSGYGFSVDGAPETRRIINVSDGVKDSDAATKGQMDNAIADAVR
ESGDALRGEIGAVYRDAVADAKSRVESAENRLNGNITAARASAQEYTDAVKSDVLDETRTYTDSSVRTVRNEVKSQAEHL
SDVLVKNRAQTDAAIASNTAAIRNNSHRLDLTEAWQKMATERMNNMQEQIKENRKELRESAAQSAALAGLFQPYSVGKFN
ATAAVGGYRDEQAIAVGVGYRFTENVAGKVAVAAGGSSASWNAGVNFEF

Sequences:

>Translated_369_residues
MLKRRDAFLKKSALAVSVALLLSSQASANKSITDSTAGIIWIDGGGQSLEKVAVIDRQLNDTGYNFAVGSGAAILDADKS
MAVGNNTAVFNADNSVALGYGSQVNGESNVLSVGAGPSGYGFSVDGAPETRRIINVSDGVKDSDAATKGQMDNAIADAVR
ESGDALRGEIGAVYRDAVADAKSRVESAENRLNGNITAARASAQEYTDAVKSDVLDETRTYTDSSVRTVRNEVKSQAEHL
SDVLVKNRAQTDAAIASNTAAIRNNSHRLDLTEAWQKMATERMNNMQEQIKENRKELRESAAQSAALAGLFQPYSVGKFN
ATAAVGGYRDEQAIAVGVGYRFTENVAGKVAVAAGGSSASWNAGVNFEF
>Mature_369_residues
MLKRRDAFLKKSALAVSVALLLSSQASANKSITDSTAGIIWIDGGGQSLEKVAVIDRQLNDTGYNFAVGSGAAILDADKS
MAVGNNTAVFNADNSVALGYGSQVNGESNVLSVGAGPSGYGFSVDGAPETRRIINVSDGVKDSDAATKGQMDNAIADAVR
ESGDALRGEIGAVYRDAVADAKSRVESAENRLNGNITAARASAQEYTDAVKSDVLDETRTYTDSSVRTVRNEVKSQAEHL
SDVLVKNRAQTDAAIASNTAAIRNNSHRLDLTEAWQKMATERMNNMQEQIKENRKELRESAAQSAALAGLFQPYSVGKFN
ATAAVGGYRDEQAIAVGVGYRFTENVAGKVAVAAGGSSASWNAGVNFEF

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes attachment to eukaryotic cells and after invasion, is the major adhesin in infected tissue. Constitutes an alternative uptake pathway under conditio

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 38790; Mature: 38790

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRRDAFLKKSALAVSVALLLSSQASANKSITDSTAGIIWIDGGGQSLEKVAVIDRQLN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCC
DTGYNFAVGSGAAILDADKSMAVGNNTAVFNADNSVALGYGSQVNGESNVLSVGAGPSGY
CCCCEEEECCCCEEEECCCCEECCCCEEEEECCCCEEECCCCCCCCCCCEEEECCCCCCC
GFSVDGAPETRRIINVSDGVKDSDAATKGQMDNAIADAVRESGDALRGEIGAVYRDAVAD
CEECCCCCCCCEEEECCCCCCCCCCHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AKSRVESAENRLNGNITAARASAQEYTDAVKSDVLDETRTYTDSSVRTVRNEVKSQAEHL
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SDVLVKNRAQTDAAIASNTAAIRNNSHRLDLTEAWQKMATERMNNMQEQIKENRKELRES
HHHHHHCCCHHHHHHHCCCHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQSAALAGLFQPYSVGKFNATAAVGGYRDEQAIAVGVGYRFTENVAGKVAVAAGGSSAS
HHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEECCCEECCCCCCEEEEEECCCCCC
WNAGVNFEF
CCCCCCCCC
>Mature Secondary Structure
MLKRRDAFLKKSALAVSVALLLSSQASANKSITDSTAGIIWIDGGGQSLEKVAVIDRQLN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCC
DTGYNFAVGSGAAILDADKSMAVGNNTAVFNADNSVALGYGSQVNGESNVLSVGAGPSGY
CCCCEEEECCCCEEEECCCCEECCCCEEEEECCCCEEECCCCCCCCCCCEEEECCCCCCC
GFSVDGAPETRRIINVSDGVKDSDAATKGQMDNAIADAVRESGDALRGEIGAVYRDAVAD
CEECCCCCCCCEEEECCCCCCCCCCHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AKSRVESAENRLNGNITAARASAQEYTDAVKSDVLDETRTYTDSSVRTVRNEVKSQAEHL
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SDVLVKNRAQTDAAIASNTAAIRNNSHRLDLTEAWQKMATERMNNMQEQIKENRKELRES
HHHHHHCCCHHHHHHHCCCHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQSAALAGLFQPYSVGKFNATAAVGGYRDEQAIAVGVGYRFTENVAGKVAVAAGGSSAS
HHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEECCCEECCCCCCEEEEEECCCCCC
WNAGVNFEF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3043229; 2761389; 2592347; 1548243; 12183532 [H]