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The map label for this gene is sgrR [H]

Identifier: 170681588

GI number: 170681588

Start: 83496

End: 85154

Strand: Reverse

Name: sgrR [H]

Synonym: EcSMS35_0074

Alternate gene names: 170681588

Gene position: 85154-83496 (Counterclockwise)

Preceding gene: 170682967

Following gene: 170682457

Centisome position: 1.68

GC content: 55.58

Gene sequence:

>1659_bases
ATGCCATCTGCTCGTCTGCAACAACAGTTCATCCGCCTGTGGCAATGCTGCGAGGGTAAATCGCAGGACACAACGCTCAA
CGAACTGGCAGCGTTATTGAGCTGCTCGCGTCGTCATATGCGCACCCTGCTCAACACCATGCAGGATCGCGGCTGGCTGA
CGTGGGAAGCGGAAGTCGGGCGCGGTAAACGCTCGCGTCTGACATTCCTCTATACCGGGCTGGCGCTTCAGCAACAGCGG
GCGGAAGACCTGCTGGAGCAGGATCGTATCGATCAACTGGTGCAACTGGTTGGCGACAAAGCGACTGTGCGGCAAATGCT
GGTTTCTCATCTGGGCCGCAGCTTCCGCCAGGGGCGACACATCCTGCGTGTGCTCTACTATCGTCCGTTGCGTAATCTGC
TACCTGGCAGCGCATTACGCCGTTCCGAAACCCATATCGCCCGGCAAATCTTCAGTTCGCTAACGCGCATAAATGAGGAA
AATGGGGAACTGGAAGCAGACATCGCCCACCACTGGCAGCAAATATCACCGCTTCACTGGCGTTTCTTTTTGCGTCCAGG
AGTCCATTTTCATCATGGTCGTGAACTGGAAATGGACGATGTGATCGCCTCTTTAAAACGGATCAATACGCTGCCGCTCT
ATTCGCATATTGCTGAAATTGTATCGCCGACGCCCTGGACGCTGGATATCCACCTCACGCAGCCGGATCGCTGGTTGCCG
TTACTGCTGGGGCAAGTTCCGGCGATGATCCTGCCGCGCGAATGGGAAACCCTCAGTAACTTTGCCAGCCATCCCATCGG
CACCGGTCCGTATGCGGTGATCCGCAACAGCACCAATCAACTGAAAATTCAGGCATTCGATGACTTCTTCGGTTACCGGG
CATTAATCGACGAAGTTAACGTCTGGGTTCTGCCGGAAATTGCCGACGAGCCAGCCGGAGGGCTGATGCTAAAAGGGCCA
CAGGGCGAGGAAAAAGAGATTGAAAGCCGCCTGGAGGAAGGTTGCTACTATTTACTGTTCGACAGCCGCACCCATCGCGG
GGCGAATCAGCAAGTCAGGGACTGGGTAAGCTATGTGCTTTCTCCAACTAATCTGGTCTATTTCGCTGAGGAACAGTACC
AGCAACTGTGGTTCCCGGCTTATGGACTGCTCCCCCGTTGGCACCATGCTCGTCCGACACATTGCGAAAAACCCGCCGGG
CTGGAAAGCCTCACCCTGACCTTTTATCAGGATCATATTGAGCATCGAGTGATTGCCGGGATCATGCAGCAGATTCTGGC
AAGTCACCAGGTCACGCTGGAAATCAAAGAGATCAGCTACGATCAGTGGCATGAAGGAGAGATCGAGAGCGATATCTGGC
TTAACAGCGCCAACTTTACGCTGCCGCTGGATTTTTCGCTGTTCGCGCACTTGTGCGAGGTGCCGCTGCTCCAACACTGT
CTTCCGATCGACTGGCAAGCCGACGCCGCCCGCTGGCGCAATGGCGAAATGAACCTGGCGAACTGGTGCCAGCAACTGGT
CGCCAGCAAAGCAATGGTGCCGCTTATCCACCACTGGCTGATCATTCAGGGGCAACGCAGTATGCGCGGTCTACGTATGA
ACACCCTCGGCTGGTTCGATTTTAAATCAGCGTGGTTTGCGCCGCCGGATCCAGAGTAG

Upstream 100 bases:

>100_bases
AAACTGACGCATGGGGCACCTCCTTGCTTCATCGTTAGGAATTATTGACTTAATATAGGGAAAATAAAATTGCTGACTTT
TGCGCAGGAGTTCCCCTTTT

Downstream 100 bases:

>100_bases
CTTGCGCCTTTTGGCGGTCATGAGCGCGTTTTTTATATTCAGACGGAATGAATAAAATACATTACTTTTATATTTTCTCT
GTTTTATGCATCGTCTGATT

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAG
LESLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
LPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE

Sequences:

>Translated_552_residues
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAG
LESLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
LPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>Mature_551_residues
PSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRA
EDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEEN
GELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLPL
LLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQ
GEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAGL
ESLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCL
PIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=551, Percent_Identity=97.8221415607985, Blast_Score=1115, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=592, Percent_Identity=27.1959459459459, Blast_Score=182, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64169; Mature: 64038

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVG
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEE
RFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
EEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCC
VWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVL
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
SPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAGLESLTLTFYQDHIEHRVIAG
CCCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHC
LPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFD
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEECCCCCCC
FKSAWFAPPDPE
CCCCCCCCCCCC
>Mature Secondary Structure 
PSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVG
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEE
RFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLTQPDRWLP
EEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCC
VWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVL
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
SPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAGLESLTLTFYQDHIEHRVIAG
CCCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHC
LPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFD
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEECCCCCCC
FKSAWFAPPDPE
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]