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The map label for this gene is ybbO [H]

Identifier: 170681540

GI number: 170681540

Start: 548699

End: 549469

Strand: Reverse

Name: ybbO [H]

Synonym: EcSMS35_0542

Alternate gene names: 170681540

Gene position: 549469-548699 (Counterclockwise)

Preceding gene: 170679602

Following gene: 170681623

Centisome position: 10.84

GC content: 54.09

Gene sequence:

>771_bases
ATGCAAAAATCGGTCTTAATTACCGGATGTTCCAGTGGAATTGGCCTGGAAAGCGCGCTCGAATTAAAACGCCAGGGTTT
TCATGTGCTGGCAGGTTGCCGGAAAGCGGATGATGTTGAGCGCATGAACAGCATGGGATTTACCGGCGTGTTGATCGATC
TGGATTCACCAGAAAGTGTTGATCGCGCAGCCGACGAAGTGATCGCCCTGACCGATAATTGTCTGTATGGGATCTTTAAC
AATGCCGGATTCGGCATGTATGGCCCCCTTTCCACCATCAGCCGTGTGCAGATGGAACAGCAGTTTTCCGCCAACTTTTT
CGGCGCACACCAGCTCACCATGCGCCTGTTACCCGTGATGTTACCGCACGGTGAAGGACGTATTGTGATGACCTCATCGG
TGATGGGATTAATCTCCACGCCGGGTCGTGGCGCTTACGCGGCCAGTAAATATGCGCTGGAGGCGTGGTCAGACGCACTG
CGCATGGAGCTACGTCACAGCGGAATTAAAGTTAGCCTGATCGAACCCGGTCCCATTCGTACTCGCTTCACCGACAACGT
CAACCAGACGCAAAGTGATAAACCTGTCGAAAATCCCGGCATCGCCGCCCGCTTTACGTTGGGACCGGAAGCGGTGGTCG
ACAAAGTGCGCCATGCTTTTATTAGCGAGAAGCCGAAGATGCGCTATCCAGTAACGCTGGTGACCTGGGCAGTAATGGTG
CTTAAGCGCCTGCTGCCGGGGCGCGTGATGGACAAAATATTGCAGGGGTGA

Upstream 100 bases:

>100_bases
CGCGACGCCCAGCCGTTTATTGCCGACTGGATGGCGAAGCAGTTGCAGCCTTTAGTAAATCATGACTCATAAAGCAACGG
AGATCCTGACAGGTAAAGTT

Downstream 100 bases:

>100_bases
GTTGAAGCGCGCGCTTAAGCCCCCATGTCAAAGAAAATATCGACAACAGAGAGCGACTCCATGTCCGTAGAAAATATTGT
CAACATTAACGAATCTAACC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKADDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFN
NAGFGMYGPLSTISRVQMEQQFSANFFGAHQLTMRLLPVMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
RMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMV
LKRLLPGRVMDKILQG

Sequences:

>Translated_256_residues
MQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKADDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFN
NAGFGMYGPLSTISRVQMEQQFSANFFGAHQLTMRLLPVMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
RMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMV
LKRLLPGRVMDKILQG
>Mature_256_residues
MQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKADDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFN
NAGFGMYGPLSTISRVQMEQQFSANFFGAHQLTMRLLPVMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
RMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMV
LKRLLPGRVMDKILQG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=38.8297872340425, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI40548397, Length=259, Percent_Identity=31.2741312741313, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI214010158, Length=259, Percent_Identity=31.2741312741313, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI214010156, Length=259, Percent_Identity=31.2741312741313, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI22758144, Length=259, Percent_Identity=31.2741312741313, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI50726952, Length=186, Percent_Identity=39.247311827957, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI150247226, Length=254, Percent_Identity=33.0708661417323, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI22507405, Length=280, Percent_Identity=30.3571428571429, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI44680136, Length=287, Percent_Identity=28.9198606271777, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI44680133, Length=287, Percent_Identity=28.9198606271777, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI17738292, Length=287, Percent_Identity=28.9198606271777, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI19743808, Length=281, Percent_Identity=30.9608540925267, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI119392083, Length=199, Percent_Identity=36.1809045226131, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI7706318, Length=269, Percent_Identity=26.3940520446097, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4504503, Length=202, Percent_Identity=33.6633663366337, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=31.413612565445, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=260, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40807363, Length=258, Percent_Identity=29.0697674418605, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI32455239, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031765, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=256, Percent_Identity=98.828125, Blast_Score=526, Evalue=1e-151,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=30.3482587064677, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789378, Length=203, Percent_Identity=29.064039408867, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=24.7368421052632, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=25.5208333333333, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=283, Percent_Identity=30.0353356890459, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563809, Length=291, Percent_Identity=27.4914089347079, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17507613, Length=291, Percent_Identity=27.4914089347079, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17557780, Length=297, Percent_Identity=28.2828282828283, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193210355, Length=264, Percent_Identity=30.6818181818182, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17570069, Length=192, Percent_Identity=31.7708333333333, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=33.5051546391753, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651139, Length=237, Percent_Identity=32.0675105485232, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356301, Length=214, Percent_Identity=28.9719626168224, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=185, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45554248, Length=200, Percent_Identity=32, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640117, Length=200, Percent_Identity=32, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28030; Mature: 28030

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKADDVERMNSMGFTGVLIDLDSPESV
CCCCEEEEECCCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCEEEEEECCCCHHH
DRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRVQMEQQFSANFFGAHQLTMRLLPVM
HHHHHHEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEPGPIR
CCCCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMV
EEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LKRLLPGRVMDKILQG
HHHHCCHHHHHHHHCC
>Mature Secondary Structure
MQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKADDVERMNSMGFTGVLIDLDSPESV
CCCCEEEEECCCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCCEEEEEECCCCHHH
DRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRVQMEQQFSANFFGAHQLTMRLLPVM
HHHHHHEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEPGPIR
CCCCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMV
EEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LKRLLPGRVMDKILQG
HHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]