| Definition | Escherichia coli SMS-3-5 chromosome, complete genome. |
|---|---|
| Accession | NC_010498 |
| Length | 5,068,389 |
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The map label for this gene is sorD [H]
Identifier: 170681378
GI number: 170681378
Start: 4577862
End: 4578668
Strand: Reverse
Name: sorD [H]
Synonym: EcSMS35_4481
Alternate gene names: 170681378
Gene position: 4578668-4577862 (Counterclockwise)
Preceding gene: 170679743
Following gene: 170681082
Centisome position: 90.34
GC content: 51.43
Gene sequence:
>807_bases ATGCAAACGTGGTTAAATTTGCAGGATAAAATCATTATTGTCACCGGCGGCGCATCCGGTATTGGTCTGGCGATTGTGGA TGAATTATTAGCACAAGGCGCGAATGTACAGATGGTCGATATTCACGGTGGCGATGGTCAATATGAAAACCATAAAGGTT ATCAGTTCTGGCCGACCGATATTTCCAGCGCCAAAGAGGTAAATCATACGGTAGCAGAAATTATCCAGCGTTTTGGTCGC ATCGACGGTCTGGTCAATAACGCCGGGGTCAATTTCCCGCGTCTGCTGGTCGATGAGAAAGCGCCTGCCGGGCAGTATGA ACTCAACGAAGCGGCATTCGAAAAAATGGTCAATATCAACCAGAAAGGCGTTTTTCTGATGTCGCAGGCGGTGGCGCGAC AGATGGTCAAACAACATGATGGCGTGATTGTGAATGTTTCCTCAGAAAGTGGGCTGGAAGGCTCAGAAGGCCAAAGCTGT TACGCCGCGACCAAAGCCGCGCTCAATAGCTTCACGCGCTCCTGGTCGAAAGAGCTGGGTAAGCACGGTATCCGTGTGGT CGGTATCGCGCCGGGGATTCTGGAAAAAACAGGACTGCGTACGCCGGAATATGAAGAAGCGCTGGCGTGGACGCGCAATA TCACCGTCGAGCAGCTGCGTGAAGGCTATACCAAAAACGCCATTCCTATTGGGCGCGCCGGAAGATTAGCAGAAGTGGCT GATTTTGTTTGTTATCTGCTGTCTGAACGCGCCAGCTATATCACCGGAGTAACCACTAACATTGCGGGCGGCAAAACGCG CGGCTAA
Upstream 100 bases:
>100_bases TAGCAGCACAGCTGAACTATTACTGAAATAAAAATCTTCCCGATGTTTACCGTAATAAAAATTACGGCGGGTCCCTATTA TCTAAAATCAGGAGTCTGTT
Downstream 100 bases:
>100_bases GGAGGCTTTATGGTCAATGCCATTTTTTGCGCCCACGGCAAATTAGCCTGCGCCATGCTGGAATCGGTTCAGATGGTGTA CGGCGATGCCAGGGTCGAGG
Product: sorbitol-6-phosphate 2-dehydrogenase
Products: NA
Alternate protein names: Glucitol-6-phosphate dehydrogenase; Ketosephosphate reductase [H]
Number of amino acids: Translated: 268; Mature: 268
Protein sequence:
>268_residues MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGGDGQYENHKGYQFWPTDISSAKEVNHTVAEIIQRFGR IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA DFVCYLLSERASYITGVTTNIAGGKTRG
Sequences:
>Translated_268_residues MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGGDGQYENHKGYQFWPTDISSAKEVNHTVAEIIQRFGR IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA DFVCYLLSERASYITGVTTNIAGGKTRG >Mature_268_residues MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGGDGQYENHKGYQFWPTDISSAKEVNHTVAEIIQRFGR IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA DFVCYLLSERASYITGVTTNIAGGKTRG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=276, Percent_Identity=31.1594202898551, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI40254992, Length=262, Percent_Identity=32.0610687022901, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=31.203007518797, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI19923817, Length=273, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=33.160621761658, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI32483357, Length=269, Percent_Identity=31.5985130111524, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI59889578, Length=245, Percent_Identity=30.2040816326531, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI31542939, Length=218, Percent_Identity=32.5688073394495, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=28.4090909090909, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI83715985, Length=183, Percent_Identity=31.1475409836066, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=33.5164835164835, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=26.2376237623762, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI126723750, Length=272, Percent_Identity=27.2058823529412, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI5031737, Length=269, Percent_Identity=27.8810408921933, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI4503817, Length=235, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=271, Percent_Identity=33.5793357933579, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=31.3432835820896, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1790717, Length=271, Percent_Identity=29.1512915129151, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1788459, Length=206, Percent_Identity=33.9805825242718, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=27.5471698113208, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI1786812, Length=269, Percent_Identity=28.6245353159851, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=266, Percent_Identity=31.5789473684211, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787905, Length=269, Percent_Identity=28.996282527881, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1789057, Length=273, Percent_Identity=27.1062271062271, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1789378, Length=280, Percent_Identity=28.2142857142857, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787820, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786701, Length=192, Percent_Identity=28.6458333333333, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=33.9622641509434, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17555706, Length=264, Percent_Identity=32.5757575757576, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17561402, Length=271, Percent_Identity=30.6273062730627, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562908, Length=275, Percent_Identity=29.0909090909091, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=29.7101449275362, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI115534694, Length=273, Percent_Identity=29.3040293040293, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=30.6859205776173, Blast_Score=91, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=28.3154121863799, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=28.158844765343, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=28.6764705882353, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=29.1044776119403, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538182, Length=214, Percent_Identity=29.4392523364486, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=26.8115942028986, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=29.9638989169675, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=30.0751879699248, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=206, Percent_Identity=27.1844660194175, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71994604, Length=265, Percent_Identity=26.4150943396226, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=28.6231884057971, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=28.7272727272727, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560332, Length=280, Percent_Identity=28.9285714285714, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=29.6028880866426, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193204405, Length=279, Percent_Identity=29.3906810035842, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560676, Length=277, Percent_Identity=25.9927797833935, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=27.6752767527675, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=28.1021897810219, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17536025, Length=274, Percent_Identity=25.9124087591241, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17508895, Length=201, Percent_Identity=25.8706467661692, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508651, Length=261, Percent_Identity=24.904214559387, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=24.4019138755981, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17567345, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=265, Percent_Identity=28.6792452830189, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI23397609, Length=267, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=5e-30, Organism=Drosophila melanogaster, GI24639444, Length=265, Percent_Identity=32.8301886792453, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24643142, Length=268, Percent_Identity=32.089552238806, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI21357041, Length=270, Percent_Identity=30.3703703703704, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21355319, Length=271, Percent_Identity=29.8892988929889, Blast_Score=98, Evalue=7e-21, Organism=Drosophila melanogaster, GI28571526, Length=279, Percent_Identity=28.673835125448, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI17737361, Length=209, Percent_Identity=32.5358851674641, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644339, Length=273, Percent_Identity=26.007326007326, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24644337, Length=213, Percent_Identity=30.9859154929577, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24665243, Length=204, Percent_Identity=31.3725490196078, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=30.8457711442786, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24665247, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21356301, Length=207, Percent_Identity=29.4685990338164, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24581726, Length=145, Percent_Identity=31.0344827586207, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.140 [H]
Molecular weight: Translated: 29052; Mature: 29052
Theoretical pI: Translated: 6.37; Mature: 6.37
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGGDGQYENHKGYQFWPTD CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEECCCC ISSAKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNIN CCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHCCC QKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKELG CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH KHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA HCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHH DFVCYLLSERASYITGVTTNIAGGKTRG HHHHHHHHHHHHHHHCCEEECCCCCCCC >Mature Secondary Structure MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGGDGQYENHKGYQFWPTD CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEECCCC ISSAKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNIN CCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHCCC QKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKELG CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH KHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA HCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHH DFVCYLLSERASYITGVTTNIAGGKTRG HHHHHHHHHHHHHHHCCEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7947968; 7652212 [H]