Click here to switch to the map view.

The map label for this gene is surE [H]

Identifier: 170681369

GI number: 170681369

Start: 2942711

End: 2943478

Strand: Reverse

Name: surE [H]

Synonym: EcSMS35_2869

Alternate gene names: 170681369

Gene position: 2943478-2942711 (Counterclockwise)

Preceding gene: 170681051

Following gene: 170682160

Centisome position: 58.08

GC content: 54.69

Gene sequence:

>768_bases
GTGATTATGCGCATATTGCTGAGTAATGATGACGGGGTACATGCACCCGGTATACAAACGCTGGCGAAAGCCTTGCGTGA
GTTTGCTGACGTTCAGGTGGTCGCCCCCGATCGTAACCGCAGCGGCGCTTCAAATTCTCTGACACTGGAATCCTCCCTGC
GCACGTTTACCTTTGAAAATGGTGATATTGCTGTGCAAATGGGAACCCCGACCGATTGCGTCTATCTTGGCGTGAATGCT
CTGATGCGTCCGCGCCCGGACATTGTTGTGTCCGGAATTAACGCCGGGCCGAATCTGGGGGATGATGTTATTTATTCCGG
TACGGTAGCCGCCGCGATGGAAGGCCGTCATTTAGGTTTTCCGGCGCTGGCCGTCTCGCTTGACGGGCATAAACATTACG
ACACTGCCGCGGCGGTAACCTGTTCAATTTTGCGCGCACTGTGTAAAGAGCCGCTGCGCACCGGACGTATTCTTAACATT
AACGTTCCGGATTTACCATTGGATCAAATCAAAGGTATTCGCGTGACGCGCTGCGGTACACGACATCCGGCAGATCAGGT
GATCCCGCAGCAAGATCCGCGCGGCAATACGCTGTACTGGATTGGCCCGCCGGGCGGTAAATGTGATGCCGGTCCGGGGA
CCGATTTTGCTGCGGTAGATGAGGGCTATGTCTCCATCACGCCGCTGCATGTGGATTTAACTGCGCATAGCGCGCAAGAT
GTGGTTTCAGACTGGTTAAACAGCGTGGGAGTTGGCACGCAATGGTAA

Upstream 100 bases:

>100_bases
AGCTGGAACTGGTGGGATGACGTCACCGTAGAAATCCGTTTCTGGCTTCCGGCGGGTAGTTTTGCAACCAGCGTTGTCAG
GGAACTTATCAACACAACAG

Downstream 100 bases:

>100_bases
GCAGACGCGTACAAGCACTTCTGGATCAATTACGTGCGCAAGGTATTCAGGATGAGCAGGTGCTGAATGCACTTGCCGCC
GTGCCGCGTGAAAAATTCGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNA
LMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNI
NVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQD
VVSDWLNSVGVGTQW

Sequences:

>Translated_255_residues
MIMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNA
LMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNI
NVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQD
VVSDWLNSVGVGTQW
>Mature_255_residues
MIMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNA
LMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNI
NVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQD
VVSDWLNSVGVGTQW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=100, Blast_Score=517, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002828 [H]

Pfam domain/function: PF01975 SurE [H]

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11 [H]

Molecular weight: Translated: 27145; Mature: 27145

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFEN
CEEEEEECCCCCCCCCCHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEECCCEEEEEEC
GDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGF
CCEEEEECCCCCEEEECHHHHCCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCC
PALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGT
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCEEEEECCC
RHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQD
CCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEEECCCHHH
VVSDWLNSVGVGTQW
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MIMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFEN
CEEEEEECCCCCCCCCCHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEECCCEEEEEEC
GDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGF
CCEEEEECCCCCEEEECHHHHCCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCC
PALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGT
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCEEEEECCC
RHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQD
CCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEEECCCHHH
VVSDWLNSVGVGTQW
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA