Click here to switch to the map view.

The map label for this gene is nuoK

Identifier: 170681200

GI number: 170681200

Start: 2481919

End: 2482221

Strand: Reverse

Name: nuoK

Synonym: EcSMS35_2433

Alternate gene names: 170681200

Gene position: 2482221-2481919 (Counterclockwise)

Preceding gene: 170681867

Following gene: 170682426

Centisome position: 48.97

GC content: 54.46

Gene sequence:

>303_bases
ATGATCCCCTTACAACATGGACTGATCCTCGCGGCAATCTTATTCGTTCTTGGCTTAACCGGTCTGGTTATCCGTCGCAA
TCTGCTGTTTATGCTGATTGGTCTGGAAATCATGATTAACGCCTCCGCGCTGGCCTTTGTGGTCGCCGGAAGCTACTGGG
GCCAGACCGACGGTCAGGTGATGTACATTCTCGCCATCAGCCTCGCGGCGGCAGAAGCAAGTATCGGCCTTGCGCTGCTG
CTGCAACTTCACCGTCGTCGCCAGAACCTGAACATCGATTCAGTAAGTGAGATGCGCGGATGA

Upstream 100 bases:

>100_bases
GTCTGGTTGTGGCCTTCCACGTTGGTCGTGAAGAGCGTGCGGGTGAAGTGCTGAGCAATCGTAAAGACGACAGCGCGAAA
AGAAAAACGGAGGAGCACGC

Downstream 100 bases:

>100_bases
ACATGCTTGCCTTAACCATTATTTTGCCATTGATTGGCTTTGTCCTGCTGGCGTTCTCCCGTGGGCGCTGGTCTGAAAAC
GTCTCGGCGATCGTGGGCGT

Product: NADH dehydrogenase subunit K

Products: NA

Alternate protein names: NADH dehydrogenase I subunit K; NDH-1 subunit K

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALL
LQLHRRRQNLNIDSVSEMRG

Sequences:

>Translated_100_residues
MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALL
LQLHRRRQNLNIDSVSEMRG
>Mature_100_residues
MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALL
LQLHRRRQNLNIDSVSEMRG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0713

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4L family

Homologues:

Organism=Escherichia coli, GI1788615, Length=100, Percent_Identity=100, Blast_Score=193, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOK_CITK8 (A8ADW0)

Other databases:

- EMBL:   CP000822
- RefSeq:   YP_001452109.1
- ProteinModelPortal:   A8ADW0
- STRING:   A8ADW0
- GeneID:   5582631
- GenomeReviews:   CP000822_GR
- KEGG:   cko:CKO_00517
- eggNOG:   COG0713
- HOGENOM:   HBG673066
- OMA:   IPMEHGL
- ProtClustDB:   PRK05715
- GO:   GO:0006810
- HAMAP:   MF_01456
- InterPro:   IPR001133

Pfam domain/function: PF00420 Oxidored_q2

EC number: =1.6.99.5

Molecular weight: Translated: 10845; Mature: 10845

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a97ba74)-; HASH(0x1aab6dc0)-; HASH(0x1a89ad34)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCE
MYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCH
>Mature Secondary Structure
MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCE
MYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA