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The map label for this gene is ompC [H]

Identifier: 170680935

GI number: 170680935

Start: 2395366

End: 2396460

Strand: Reverse

Name: ompC [H]

Synonym: EcSMS35_2364

Alternate gene names: 170680935

Gene position: 2396460-2395366 (Counterclockwise)

Preceding gene: 170679899

Following gene: 170681131

Centisome position: 47.28

GC content: 48.68

Gene sequence:

>1095_bases
ATGAAAGTTAAAGTACTGTCCCTCCTGGTCCCAGCTCTGCTGGTAGCAGGCGCAGCAAACGCTGCTGAAATTTACAACAA
AGACGGCAACAAATTAGATCTGTACGGTAAAGTTGACGGCCTGCACTATTTCTCCGATAACGACTCTAAAGATGGCGACA
AGACCTACATGCGTCTTGGCTTCAAAGGTGAAACTCAGGTTACTGATCAACTGACCGGTTATGGTCAGTGGGAATATCAG
ATTCAAGGTAACGAACCTGAAAGTGACAATAGTTCCTGGACCCGTGTGGCATTCGCTGGTCTGAAATTCCAGGACGTTGG
TTCTTTTGACTATGGTCGTAACTACGGCGTTGTTTACGATGTTACTTCCTGGACCGACGTACTGCCAGAATTCGGTGGTG
ATACCTACGATTCTGATAACTTCATGCAGCAGCGTGGTAACGGTTTCGCGACCTACCGTAACACCGACTTCTTCGGTCTG
GTTGACGGTCTTGATTTTGCTGTTCAGTATCAGGGTAAAAACGGTAGTGCTCATGGCGAAGGTATGACCACTAATGGCCG
TGATGATGTATTTGAGCAGAACGGTGACGGTGTTGGTGGTTCTATTACTTACAATTATGAAGGCTTTGGTATCGGTGCTG
CAGTTTCCAGCTCCAAACGTACCTGGGATCAGAACAACACTGGCCTGATCGGTACTGGCGACCGTGCTGAAACCTACACT
GGTGGTCTGAAATACGACGCTAACAACATCTACCTGGCTGCTCAGTACACCCAGACCTACAACGCAACTCGCGTAGGTTC
CCTGGGTTGGGCGAACAAAGCACAGAACTTCGAAGCTGTTGCTCAGTACCAGTTCGACTTCGGTCTGCGTCCGTCCCTGG
CTTACCTGCAGTCTAAAGGTAAAAACCTGGGTCGTGGCTACGACGACGAAGATATCCTGAAATATGTTGATGTTGGTGCG
ACCTACTACTTCAACAAAAACATGTCCACCTACGTTGACTACAAAATCAACCTGCTGGACGACAACCAGTTCACCCGCGC
TGCTGGCATCAACACTGATGACATCGTAGCTCTGGGTCTGGTTTACCAGTTCTAA

Upstream 100 bases:

>100_bases
ATTTTTGGGGAGAATGGACCTGCCGACTGATTAATGAGGGTTAATCAGTATGCAGTGGCATAAAAAAGCAAATAAAGGCA
TATAACAGAGGGTTAATAAC

Downstream 100 bases:

>100_bases
TCTCGATTTATATCGAACAAAGGGCCTGCGGGCCCTTTTTTCATTGTTTTCAGCGTACAAACACAGTTTTTTGGTGTACT
CTTGCGACCGTTCGCATGAG

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Outer membrane protein 1B; Porin ompC [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGL
VDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYT
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGA
TYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF

Sequences:

>Translated_364_residues
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGL
VDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYT
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGA
TYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF
>Mature_364_residues
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGL
VDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYT
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGA
TYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=368, Percent_Identity=89.945652173913, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1787641, Length=379, Percent_Identity=67.8100263852243, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1786436, Length=369, Percent_Identity=59.0785907859079, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1787160, Length=378, Percent_Identity=59.5238095238095, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 40240; Mature: 40240

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEE
FKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAHGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
GMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYT
CCCCCCCCCHHHCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCEEEECCCCCCEEC
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKG
CCEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCC
KNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGL
CCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCEEEECCCCCCCEEEEEE
VYQF
EECC
>Mature Secondary Structure
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEE
FKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAHGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
GMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYT
CCCCCCCCCHHHCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCEEEECCCCCCEEC
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKG
CCEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCC
KNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGL
CCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCEEEECCCCCCCEEEEEE
VYQF
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]