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The map label for this gene is yfaS [H]

Identifier: 170680850

GI number: 170680850

Start: 2413395

End: 2417909

Strand: Reverse

Name: yfaS [H]

Synonym: EcSMS35_2376

Alternate gene names: 170680850

Gene position: 2417909-2413395 (Counterclockwise)

Preceding gene: 170681110

Following gene: 170680053

Centisome position: 47.71

GC content: 53.42

Gene sequence:

>4515_bases
GTGGGAACAGGGCTTGCTAATGCTGATGATTCGCTTCCTTCCAGTAACTATGCGCCGCCCGGCGGGGGAACATTCTTTTT
GCTCGCTGACAGCAGTTTTAGCAGCAGTGAAGAGGCGAAAGTGCGACTGGAAGCGCCGGGGCGTGATTATCGACGCTATC
AGATGGAAGAGTACGGTGGCGTGGACGTTCGCCTGTATCGTATTCCTGACCCGATGGCATTTTTGCGCCAGCAGAAAAAC
CTGCATCGCATTGTGGTGCAACCGAAATATCTGGGCGACGGGCTAAACAATACGCTGACCTGGCTGTGGGATAACTGGTA
TGGCAAATCTCGCCGTGTAATGCAGCGTACTTTCTCTTCTCAGTCACGGCAGAATGTGACTCAGGCGTTACCCGAATTAC
AGCTCGGTAATGCCATTGTTAAACCTTCCCGTTATGTACAGAACAGCCAGTTTTCACCGCTGAAAAAATATCCACTGGTG
GAACAGTTCCGTTACCCATTATGGCAGGCTAAACCAGTCGAGCCGCAGCAAGGGGTAAAACTGGAAGGCGCATCCAGCAA
TTTCATCTCGCCGCAGCCGGGTAACATCTATATTCCTCTCGGCAAACAAGAGCCGGGACTGTATCTCGTCGAAGCGATGG
TCGGTGGGTATCGGGCAACGACGGTGGTATTTGTCTCCGATACAGTGGCGCTTAGCAAAGTGTCAGGCAACGAACTTCTG
GTGTGGACCGCGGGCAAAAAACAGGGTGAAGCGAAGCCAGGCTCAGAGATCCTGTGGACTGACGGTCTTGGCGTGATGAC
TCGCGGTGTGACCGATGACAGCGGTACCTTGCAGTTACAACATATATCGCCAGAACGTTCATACATTCTGGGTAAGGATG
CTGAAGGCGGCGTTTTTGTCTCCGAGAACTTTTTCTACGAAAGTGAAATCTACAACACCCGCTTGTATATCTTTACCGAT
CGCCCGCTATATCGCGCAGGCGATCGTGTCGATGTTAAAGTGATGGGGCGCGAGTTCCACGATCCGTTGCATTCATCCCC
CATCGTCAGCGCCCCGGCGAAGCTTTCGGTGCTGGACGCTAACGGCAGTCTGTTGCAAACCATCAATGTCACGCTGGATG
CGCGCAATGGCGGGCAGGGGAGTTTCCGCCTGCCAGAAAATGCCGTTGCCGGAGGTTATGAGTTGCGTCTTGCTTACCGC
AATCAGGTCTATAGCAGTAGTTTTCGCGTGGCAAACTACATCAAGCCACATTTCGAGATTGGCTTAGCTCTCGACAAAAA
AGAGTTCAAAACTGGCGAAGCGGTCAGCGGCAAACTGCAACTGCTCTACCCGGATGGTGAGCCGGTAAAAGATGCCCGTG
TGCAGTTAAGTTTGCGCGCTCAGCAATTATCAATGGTCGGTAACGATTTGCGTTATGCCGGACGTTTTCCCGTGTCGCTG
GAAGGCAGTGAAACGGTATCCGACGATAGCGGTCATGTGGCGTTAAATCTCCCCGCCGCTGATAAACCAAGCCGCTATTT
GTTAACCGTCTCCGCCAGTGACGGTGCGGCGTATCGTGTCACCACCACCAAAGAGATCCTCATTGAACGTGGACTGGCAC
ATTACTCATTAAGTACTGCCGCACAATACAGTAATAGCGGTGAATCGGTTGTGTTCCGTTATGCCGCGCTGGAATCTTCA
AAACAGGTTCCTGTTACGTATGAATGGTTGCGTCTCGAAGACCGCACGAGCCATAGCGGAGAGCTACCGTCAGGCGGCCA
ATCCTTTACCGTCAATTTCGCTAAACCTGGCAACTACAATCTGACATTACGCGATAAAGACGGCTTAATTCTCGCTGGGT
TAAGTCATGCCGTCAGCGGTAAGGGCAGCACGGCGCATACTGGTACGGTAGATATCGTGGCGGATAAAACGCTGTATCAG
CCAGGCGAAACTGCGAAGATGCTGATTACCTTTCCGGAGCCAATTGATGAAGCATTATTGACGCTGGAACGCGATCGCGT
GGAACAGCAGTCGCTGCTTTCGCATCCGGCAAACTGGCTGACGTTACAACGTTTAAACGATACCCAGTATGAAGCCCGGG
TTCCAGTGAGCAATTCCTTTGCGCCTAACATCACTTTTTCGGTGCTGTATACCCGTAACGGTCAGTACAGTTTTCAGAAC
GCCGGGATCAAAGTTGCCGTTCCCCAGCTGGATATCCGGGTGAAAACGGACAAAACCCATTACCAGCCTGGTGAACTGGT
CAATGTCGAATTAACCTCGTCGCTGAAAGGTAAACCTGTTTCTGCGCAGTTAACGGTAGGCGTGGTCGATGAAATGATCT
ACGCGCTGCAACCGGAAATCGCGCCGAATATCGGCAAATTTTTCTATCCGCTGGGGCGTAACAATGTGCGTACCAGCTCC
AGTTTGTCGTTTATCAGCTACGACCAGGCGCTCTCCAGCGAGCCGGTTGCGCCTGGCGCAACTAACCGCAGCGAGCGGCG
AGTAAAAATGCTTGAACGTCCACGGCGTGAAGAGGTGGATACCGCGGCATGGATGCCGTCACTCACAACCGATAAACAAG
GCAAAGCGTATTTCACGTTCCTGATGCCTGATTCGTTAACCCGCTGGCGTATCACCGCGCGTGGGATGAACGGCGACGGG
CTGGTCGGGCAGGGGCGTGCTTATCTGCGTTCGGAAAAAAATCTCTACATGAAGTGGAGTATGCCAACGGTGTATCGCGT
GGGCGACAAACCGGCGGCAGGACTGTTTATCTTCAGTCAGCAGGATAACGAACCGGTGGCGCTGGTGACTAAATTTGCAG
GCGCTGAGATGCGCCAGACGCTGACGCTGCACAAAGGGGCGAATTATATTTCGCTGACGCAGAATATTCAGCAATCTGGC
TTGTTAAGCGCAGAACTGCAACAAAATGGGCAAGTGCAGGACAGCATTAGCACAAAACTGTCTTTTGTGGATAACAGCTG
GCCCGTTGAACAGCAGAAAAATGTCATGCTCGGCGGTGGCGATAATGCGCTGATGTTGCCCGAGCAGGCGAGCAATATCC
GGCTACAAAGTAGTGAAACGCCGCAGGAGATTTTCCGTAACAATCTTGATGCGTTAGTCGATGAACCGTGGGGTGGCGTG
ATCAACACCGGTAGCCGTCTGATCCCGATCAGTCTCGCCTGGCGTTCGCTTGCCGATCATCAAAGTGCCGCCGCTAACGA
CATTCGTCAGATGATTCAGGATAACCGTCTGCGGCTGATGCAACTGGCAGGGCCCGGTGCGCGCTTTACCTGGTGGGGTG
AAGATGGCAATGGTGACGCCTTCCTCACGGCATGGGCATGGTACGCCGACTGGCAGGCCAGCCAGGCGCTCGGCGTAACG
CAACAACCGGAATACTGGCAGCATATGCTCGACAGTTATGCCGAGCAGGCAGATAACATGCCGTTATTGCATCGGGCGCT
GGTGCTGGCGTGGGCGCAGGAGATGAATCTGCCGTGCAAAACGTTGTTGAAAGGGTTGGATGAAGCTATCGCCCGGCGCG
GAACTAAAACTAAAGATTTCTCTGAGGCAGACACCAGCGATATCAATGACAGTCTGATCCTCGATACACCTGAATCTCCA
CTGGCAGATGCGGTGGCAAACGTCTTAACCATGACGTTGCTGAAAAAAGCGCAGTTGAAGTCCACTGTGATGCCACAGGT
TCAGCAATATGCGTGGGATAAAGCGGCAAACAGCAATCAGCCGCTGGCGCACACGGTTGTGCTGCTCAATAGCGGGGGCG
ACGCTACCCAGGCTGCTGCTATTTTAAGTGGTTTGACCGCTGAGCAATCCACTATTGAGCGCGCGCTGGCCATGAACTGG
CTGGCGAAATATATGGCGACAATGCCTCCGGTTGTGTTGCCTGCGCCTGCGGGCGCATGGGCCAAACATAAGTTAACTGG
AGGGGGCGAATACTGGCGTTGGGTTGGTCAGGGCGTGCCGGACATTCTCTCTTTTGGTGATGAATTGTCGCCGCAAAATG
TGCAGGTCCGCTGGCGTGAACCGGCAAAAACGGCTCAACAAAGTAACATTCCGGTGACCGTTGAACGCCAGTTGTATCGG
CTTATCCCCGGTGAAGAAGAGATGAGCTTTACTCTGCAGCCGGTGACCAGCAATGAGATTGACAGCGATGCGCTGTATCT
CGATGAAATTACGCTTACCAGCGAGCAGGATGCCGTTCTGCGCTACGGTCAGGTGGAAGTACCGCTCCCGCCAGGGGCTG
ACGTTGAGAGGACTACGTGGGGCATTTCGGTCAATAAACCGAACGCTGGAAAACAGCAGGGGCAGTTGCTGGAAAAAGCG
CGAAATGAAATGGGCGAACTGGCCTATATGGTGCCGGTGAAAGAACTGACGGGAACGGTCACTTTCCGCCATTTGCTGCG
CTTCTCGCAAAAAGGGCAATTCGTTCTGCCTCCTGCTCGTTATGTGCGTTCCTATGCACCTGCACAGCAAAGTGTTGCGG
CAGGGAGCGAATGGACCGGGATGCAGGTGAAATAA

Upstream 100 bases:

>100_bases
AGGACACCCGATGGATACCCAACGATTCCAATCCCAATTTCATTGGCATTTATCGTTTAAATTTTCTGGCGCGATAGCAG
CGTGCTTTTGCCTGTCTCTT

Downstream 100 bases:

>100_bases
GTGAACTGGCGCAGAATCGTCTGGCTATTAGCGTTGGTTACTCTGCCAACGCTTGCGGAGGAGACGTCGTTACAACTGGC
GCTGCGGGGCGCGCAGCATG

Product: alpha-2-macroglobulin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1504; Mature: 1503

Protein sequence:

>1504_residues
MGTGLANADDSLPSSNYAPPGGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKN
LHRIVVQPKYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIVKPSRYVQNSQFSPLKKYPLV
EQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELL
VWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTD
RPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTINVTLDARNGGQGSFRLPENAVAGGYELRLAYR
NQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKDARVQLSLRAQQLSMVGNDLRYAGRFPVSL
EGSETVSDDSGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESS
KQVPVTYEWLRLEDRTSHSGELPSGGQSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQ
PGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQN
AGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSS
SLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDG
LVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSG
LLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGV
INTGSRLIPISLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVT
QQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTKDFSEADTSDINDSLILDTPESP
LADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNW
LAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYR
LIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKA
RNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK

Sequences:

>Translated_1504_residues
MGTGLANADDSLPSSNYAPPGGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKN
LHRIVVQPKYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIVKPSRYVQNSQFSPLKKYPLV
EQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELL
VWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTD
RPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTINVTLDARNGGQGSFRLPENAVAGGYELRLAYR
NQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKDARVQLSLRAQQLSMVGNDLRYAGRFPVSL
EGSETVSDDSGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESS
KQVPVTYEWLRLEDRTSHSGELPSGGQSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQ
PGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQN
AGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSS
SLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDG
LVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSG
LLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGV
INTGSRLIPISLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVT
QQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTKDFSEADTSDINDSLILDTPESP
LADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNW
LAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYR
LIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKA
RNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>Mature_1503_residues
GTGLANADDSLPSSNYAPPGGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNL
HRIVVQPKYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIVKPSRYVQNSQFSPLKKYPLVE
QFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELLV
WTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDR
PLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTINVTLDARNGGQGSFRLPENAVAGGYELRLAYRN
QVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKDARVQLSLRAQQLSMVGNDLRYAGRFPVSLE
GSETVSDDSGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSK
QVPVTYEWLRLEDRTSHSGELPSGGQSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQP
GETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNA
GIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSS
LSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGL
VGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGL
LSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVI
NTGSRLIPISLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQ
QPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTKDFSEADTSDINDSLILDTPESPL
ADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNWL
AKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRL
IPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKAR
NEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK

Specific function: Unknown

COG id: COG2373

COG function: function code R; Large extracellular alpha-helical protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0192 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002890
- InterPro:   IPR011625
- InterPro:   IPR001599
- InterPro:   IPR008930 [H]

Pfam domain/function: PF00207 A2M; PF01835 A2M_N; PF07703 A2M_N_2 [H]

EC number: NA

Molecular weight: Translated: 166278; Mature: 166146

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTGLANADDSLPSSNYAPPGGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGG
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCC
VDVRLYRIPDPMAFLRQQKNLHRIVVQPKYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSS
EEEEEEECCCHHHHHHHHCCCEEEEEECHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHH
QSRQNVTQALPELQLGNAIVKPSRYVQNSQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVK
HHHHHHHHHCCCHHCCCEEECCHHHHCCCCCCCHHCCCCHHHHCCCCCCCCCCCCCCCEE
LEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELL
EECCCCCCCCCCCCEEEEECCCCCCCEEEEEHHHCCEEEEEEEEEECCEEEEEECCCEEE
VWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFV
EEECCCCCCCCCCCCEEEEECCCCCEECCCCCCCCEEEEEEECCCCCEEECCCCCCCEEE
SENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDA
ECCEEEECEEEEEEEEEEECCCHHHCCCEEEEEEECCHHCCCCCCCCCCCCCCEEEEEEC
NGSLLQTINVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEI
CCCEEEEEEEEEECCCCCCCCEECCCCCCCCCEEEEEEEHHHHHCCCCHHHHHCCCCEEE
GLALDKKEFKTGEAVSGKLQLLYPDGEPVKDARVQLSLRAQQLSMVGNDLRYAGRFPVSL
EEEECHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHHHCCCHHCCCCCCEEE
EGSETVSDDSGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTA
CCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECHHHHHHHCCCHHHHHHHH
AQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGQSFTVNFAKPGNYN
HHHCCCCCEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCEE
LTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALL
EEEECCCCEEEEECHHHHCCCCCCCCCCEEEEEECCEECCCCCCEEEEEECCCCHHHHHH
TLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQN
HHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEEECCCEEEEC
AGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEI
CCEEEEECEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHCCCC
APNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVD
CCCCCHHEEECCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHCC
TAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWS
HHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHEEECCCCEEEEEC
MPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSG
CCEEEEECCCCCCEEEEEECCCCCCEEEEEECCCCHHHHEEEECCCCCEEEEHHHHHHCC
LLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSET
CEEHHHHHCCCCHHHHHHEEEEECCCCCCCCCCCEEEECCCCEEECCCCCCCEEEECCCC
PQEIFRNNLDALVDEPWGGVINTGSRLIPISLAWRSLADHQSAAANDIRQMIQDNRLRLM
HHHHHHCCCHHHHCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
QLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNM
EECCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTKDFSEADTSDINDSLILDTPESP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCC
LADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHH
ILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVP
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCHHHHHHHCCCH
DILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEI
HHHHCCCCCCCCCEEEEECCCHHHHHHCCCCEEEHHHHHHHCCCCCCCEEEEEECCCCCC
DSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKA
CCCEEEEEEEEECCCCCHHEEECEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
RNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTG
HHHHCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCHHHHCCCCCCCC
MQVK
CEEC
>Mature Secondary Structure 
GTGLANADDSLPSSNYAPPGGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGG
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCC
VDVRLYRIPDPMAFLRQQKNLHRIVVQPKYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSS
EEEEEEECCCHHHHHHHHCCCEEEEEECHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHH
QSRQNVTQALPELQLGNAIVKPSRYVQNSQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVK
HHHHHHHHHCCCHHCCCEEECCHHHHCCCCCCCHHCCCCHHHHCCCCCCCCCCCCCCCEE
LEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELL
EECCCCCCCCCCCCEEEEECCCCCCCEEEEEHHHCCEEEEEEEEEECCEEEEEECCCEEE
VWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFV
EEECCCCCCCCCCCCEEEEECCCCCEECCCCCCCCEEEEEEECCCCCEEECCCCCCCEEE
SENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDA
ECCEEEECEEEEEEEEEEECCCHHHCCCEEEEEEECCHHCCCCCCCCCCCCCCEEEEEEC
NGSLLQTINVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEI
CCCEEEEEEEEEECCCCCCCCEECCCCCCCCCEEEEEEEHHHHHCCCCHHHHHCCCCEEE
GLALDKKEFKTGEAVSGKLQLLYPDGEPVKDARVQLSLRAQQLSMVGNDLRYAGRFPVSL
EEEECHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHHHCCCHHCCCCCCEEE
EGSETVSDDSGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTA
CCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECHHHHHHHCCCHHHHHHHH
AQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGQSFTVNFAKPGNYN
HHHCCCCCEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCEE
LTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALL
EEEECCCCEEEEECHHHHCCCCCCCCCCEEEEEECCEECCCCCCEEEEEECCCCHHHHHH
TLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQN
HHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEEECCCEEEEC
AGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEI
CCEEEEECEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHCCCC
APNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVD
CCCCCHHEEECCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHCC
TAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWS
HHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHEEECCCCEEEEEC
MPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSG
CCEEEEECCCCCCEEEEEECCCCCCEEEEEECCCCHHHHEEEECCCCCEEEEHHHHHHCC
LLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSET
CEEHHHHHCCCCHHHHHHEEEEECCCCCCCCCCCEEEECCCCEEECCCCCCCEEEECCCC
PQEIFRNNLDALVDEPWGGVINTGSRLIPISLAWRSLADHQSAAANDIRQMIQDNRLRLM
HHHHHHCCCHHHHCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
QLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNM
EECCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTKDFSEADTSDINDSLILDTPESP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCC
LADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHH
ILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVP
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCHHHHHHHCCCH
DILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEI
HHHHCCCCCCCCCEEEEECCCHHHHHHCCCCEEEHHHHHHHCCCCCCCEEEEEECCCCCC
DSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKA
CCCEEEEEEEEECCCCCHHEEECEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
RNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTG
HHHHCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCHHHHCCCCCCCC
MQVK
CEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]