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The map label for this gene is dgoT [H]

Identifier: 170680666

GI number: 170680666

Start: 1109201

End: 1110493

Strand: Reverse

Name: dgoT [H]

Synonym: EcSMS35_1094

Alternate gene names: 170680666

Gene position: 1110493-1109201 (Counterclockwise)

Preceding gene: 170680994

Following gene: 170683881

Centisome position: 21.91

GC content: 52.59

Gene sequence:

>1293_bases
ATGGATATTCCCGTTAATGCAGCAAAGCCGGGGCGTCGGCGTTATCTGACGCTGGTGATGATCTTTATTACGGTGGTCAT
TTGTTATGTTGACCGCGCTAACCTGGCCGTGGCTGCCGCCCATATTCAGGAAGAGTTCGGCATTACCAAAGCGGAAATGG
GCTATGTATTTTCGGCCTTCGCCTGGCTTTATACGCTATGTCAGATCCCCGGCGGTTGGTTTTTAGATCGCGTAGGTTCA
CGCGTGACTTATTTTATTGCGATATTTGGCTGGTCAGTGGCGACGTTATTCCAGGGCTTTGCCACGGGATTAATGTCATT
AATTGGTCTGCGCGCGATAACCGGTATTTTCGAAGCGCCCGCTTTCCCGACCAATAACCGGATGGTGACCAGCTGGTTCC
CGGAACATGAACGCGCTTCTGCCGTTGGTTTTTATACGTCTGGTCAGTTTGTCGGTCTGGCGTTTCTGACTCCGCTGCTG
ATCTGGATTCAGGAGATGTTGAGCTGGCACTGGGTGTTCATTGTCACCGGTGGTATCGGCATTATCTGGTCGCTGATTTG
GTTTAAGGTTTATCAGCCGCCGCGCCTGACCAAAGGCATCAGCAAAGCTGAACTGGATTACATTCGTGATGGCGGCGGTC
TGGTGGATGGTGATGCGCCGGTGAAAAAAGAGGCACGTCAGCCGTTAACAGCCAAAGACTGGAAACTGGTGTTCCATCGT
AAACTGATCGGCGTCTATCTTGGACAATTTGCGGTGACTTCTACACTGTGGTTTTTTTTGACCTGGTTCCCGAACTATTT
AACCCAGGAAAAAGGAATCACGGCGCTGAAAGCAGGCTTTATGACCTCGGTACCATTCCTCGCGGCGTTTGTCGGCGTCC
TGCTCTCTGGCTGGGTCGCGGATCTGCTGGTACGTAAGGGCTTTTCACTGGGCTTTGCGCGTAAAACGCCGATTATCTGC
GGCTTGCTGATCTCCACCTGCATTATGGGCGCTAACTACACTAACGATCCGATGATGATTATGTGCCTGATGGCGCTGGC
ATTCTTCGGCAACGGTTTTGCTTCGATTACCTGGTCGCTGGTCTCTTCTCTGGCACCGATGCGCCTGATTGGTTTAACCG
GTGGCGTATTTAACTTTGTTGGCGGTCTGGGCGGCATCACCGTTCCGCTGGTGGTGGGGTACCTGGCGCAGGGTTACGGT
TTCGCACCTGCACTGGTTTATATCTCCGCCGTCGCGTTGATTGGCGCGCTCTCTTACATTCTGATGGTGGGCGATGTGAA
GCGCGTTGGATAA

Upstream 100 bases:

>100_bases
TCATCGGGCACTAAAACAGCAATACAAAAATATAACCCTCTGTAAATTACAGGGCATGGTGAGCGGCTTCGCTATGCCCA
AAATCAGGAGAAAGCTCGCT

Downstream 100 bases:

>100_bases
TCTCTTATCTGAGGAAGCCCTTTTTTCTCATACCTGTGCTGAACAGATAGAAATATTCAGTAACCATCTCACCTGGTGGG
AAGAAATAAATATCCTCCGG

Product: d-galactonate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVAAAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGS
RVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLL
IWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
KLIGVYLGQFAVTSTLWFFLTWFPNYLTQEKGITALKAGFMTSVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIIC
GLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFVGGLGGITVPLVVGYLAQGYG
FAPALVYISAVALIGALSYILMVGDVKRVG

Sequences:

>Translated_430_residues
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVAAAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGS
RVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLL
IWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
KLIGVYLGQFAVTSTLWFFLTWFPNYLTQEKGITALKAGFMTSVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIIC
GLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFVGGLGGITVPLVVGYLAQGYG
FAPALVYISAVALIGALSYILMVGDVKRVG
>Mature_430_residues
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVAAAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGS
RVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLL
IWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
KLIGVYLGQFAVTSTLWFFLTWFPNYLTQEKGITALKAGFMTSVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIIC
GLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFVGGLGGITVPLVVGYLAQGYG
FAPALVYISAVALIGALSYILMVGDVKRVG

Specific function: Intake of galactonate into the cell [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=420, Percent_Identity=25.7142857142857, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI9945322, Length=410, Percent_Identity=25.3658536585366, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI21322234, Length=407, Percent_Identity=24.0786240786241, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI154350196, Length=412, Percent_Identity=23.7864077669903, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI9966811, Length=408, Percent_Identity=23.2843137254902, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI148743791, Length=381, Percent_Identity=27.0341207349081, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI148728191, Length=301, Percent_Identity=27.5747508305648, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI223718438, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5031955, Length=264, Percent_Identity=24.6212121212121, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=98.8372093023256, Blast_Score=856, Evalue=0.0,
Organism=Escherichia coli, GI1789152, Length=435, Percent_Identity=42.5287356321839, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1789515, Length=435, Percent_Identity=41.1494252873563, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI2367379, Length=435, Percent_Identity=28.9655172413793, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI2367193, Length=410, Percent_Identity=27.0731707317073, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788573, Length=442, Percent_Identity=23.9819004524887, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082071, Length=423, Percent_Identity=21.7494089834515, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082404, Length=360, Percent_Identity=23.6111111111111, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533554, Length=424, Percent_Identity=25, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115533556, Length=423, Percent_Identity=25.0591016548463, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71997452, Length=407, Percent_Identity=24.0786240786241, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17552542, Length=367, Percent_Identity=25.6130790190736, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=427, Percent_Identity=23.6533957845433, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=377, Percent_Identity=25.4641909814324, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI86561091, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=263, Percent_Identity=23.1939163498099, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=263, Percent_Identity=23.1939163498099, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=239, Percent_Identity=23.4309623430962, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=361, Percent_Identity=23.5457063711911, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=332, Percent_Identity=24.0963855421687, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45550460, Length=318, Percent_Identity=25.1572327044025, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24648416, Length=409, Percent_Identity=25.1833740831296, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21356189, Length=409, Percent_Identity=25.1833740831296, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24655255, Length=278, Percent_Identity=25.5395683453237, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573299, Length=410, Percent_Identity=23.9024390243902, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24655271, Length=408, Percent_Identity=23.2843137254902, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20130135, Length=408, Percent_Identity=23.2843137254902, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24658658, Length=410, Percent_Identity=23.9024390243902, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20130167, Length=439, Percent_Identity=23.9179954441913, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI62484226, Length=405, Percent_Identity=24.9382716049383, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639764, Length=417, Percent_Identity=23.9808153477218, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573708, Length=342, Percent_Identity=22.5146198830409, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573707, Length=342, Percent_Identity=22.5146198830409, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24658674, Length=410, Percent_Identity=23.4146341463415, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653727, Length=387, Percent_Identity=25.3229974160207, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922400, Length=424, Percent_Identity=24.7641509433962, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654215, Length=424, Percent_Identity=24.7641509433962, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550495, Length=406, Percent_Identity=22.1674876847291, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583789, Length=380, Percent_Identity=22.3684210526316, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658689, Length=410, Percent_Identity=22.9268292682927, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45552797, Length=410, Percent_Identity=22.9268292682927, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920686, Length=390, Percent_Identity=22.0512820512821, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580790, Length=389, Percent_Identity=24.4215938303342, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584153, Length=300, Percent_Identity=21.6666666666667, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641682, Length=290, Percent_Identity=24.4827586206897, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129235, Length=273, Percent_Identity=24.5421245421245, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281361682, Length=346, Percent_Identity=22.5433526011561, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550364, Length=220, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47123; Mature: 47123

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVAAAHIQEEFGITKAEMGYVFSAF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAP
HHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIG
CCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCHH
IIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
KLIGVYLGQFAVTSTLWFFLTWFPNYLTQEKGITALKAGFMTSVPFLAAFVGVLLSGWVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VSSLAPMRLIGLTGGVFNFVGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYI
HHHCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LMVGDVKRVG
HHHCCHHHCC
>Mature Secondary Structure
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVAAAHIQEEFGITKAEMGYVFSAF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAP
HHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIG
CCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCHH
IIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
KLIGVYLGQFAVTSTLWFFLTWFPNYLTQEKGITALKAGFMTSVPFLAAFVGVLLSGWVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VSSLAPMRLIGLTGGVFNFVGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYI
HHHCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LMVGDVKRVG
HHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]