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The map label for this gene is yfdE [H]

Identifier: 170680633

GI number: 170680633

Start: 2578843

End: 2579988

Strand: Reverse

Name: yfdE [H]

Synonym: EcSMS35_2521

Alternate gene names: 170680633

Gene position: 2579988-2578843 (Counterclockwise)

Preceding gene: 170680123

Following gene: 170682886

Centisome position: 50.9

GC content: 44.85

Gene sequence:

>1146_bases
ATGACAAATAATGAAAGCAAAGGGCCGTTTGAAGGCTTATTAGTTATCGATATGACGCATGTCCTTAATGGGCCTTTCGG
AACTCAACTTCTTTGTAATATGGGCGCAAGGGTAATTAAAGTTGAGCCGCCAGGTCATGGTGATGATACCCGCACATTTG
GTCCCTATGTGGATGGACAGTCACTCTATTACAGTTTTATTAATCATGGCAAAGAGAGTGTGGTTCTTGATTTAAAGAAT
GATCACGATAAAAGTATATTTATAAATATGCTTAAACAAGCTGATGTATTAGCTGAGAATTTTCGCCCAGGTACAATGGA
AAAACTGGGGTTTTCATGGGAAAGGTTACAAGAAATCAACCCGCGCCTTATATATGCTTCATCGTCAGGTTTCGGACATA
CCGGTCCGCTAAAAGATGCTCCTGCCTACGATACCATCATTCAGGCAATGAGCGGGATAATGATGGAAACAGGATACCCT
GATGCTCCGCCAGTGCGCGTTGGTACCTCTCTTGCGGATCTATGTGGTGGTGTTTATTTATTCAGCGGAATAGTGAGTGC
ACTTTATGGCCGCGAAAAGAGCCAGAGAGGTGCGCATGTCGATATAGCGATGTTTGATGCCACGCTGAGTTTTCTGGAGC
ATGGACTGATGGCATATATCGCGACTGGGAAGTCACCACAACGCCTGGGAAATCGCCATCCCTACATGGCACCTTTTGAT
GTTTTTGATACTCAGGATAAGCCGATTACAATTTGTTGTGGTAATGACAAGCTTTTTTCTGCGTTATGCCAGGCACTGGA
GCTTACAGAACTGGTTAATGATCCCCGATTTAGCAGCAATATTTTACGCGTACAAAACCAGGCTATTCTTAAACAATATA
TTGAGCGAACGTTAAAAACGCAGGCAGCTGAAGTTTGGTTAGCCAGAATACATGAAGTTGGTGTACCCGTCGCGCCGTTA
TTAAGTGTGGCTGAGGCCATTAATTTGCCACAAACTCAGGCGAGAAATATGTTGATTGAAGCCGGAGGAATAATGATGCC
AGGTAATCCGATAAAAATCAGCGGCTGCGCGGACCCGCATGTTATGCCGGGAGCGGCAACGCTCGACCAGCATGGGGAAC
AAATTCGCCAGGAGTTCTCATCATAA

Upstream 100 bases:

>100_bases
ATTTATGTCAGTCGACTGGTTTCATAATTAATCATGTTATTGATTTTACATAAATGCCGAAGTGTCTTTTCACCTTCGGC
TTTTTTCAAGGCATAAGCAA

Downstream 100 bases:

>100_bases
ATGTAAGATGTGCTGGTAAATAGCTCCCACATTAGAACATTGTGGGAGCCGCAATTTAGTCATTTTTCTGACAGAAAACA
GCAATCTCCTGGTCCAGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKN
DHDKSIFINMLKQADVLAENFRPGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
VFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPL
LSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS

Sequences:

>Translated_381_residues
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKN
DHDKSIFINMLKQADVLAENFRPGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
VFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPL
LSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS
>Mature_380_residues
TNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKND
HDKSIFINMLKQADVLAENFRPGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPD
APPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFDV
FDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLL
SVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=376, Percent_Identity=32.9787234042553, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI300863124, Length=324, Percent_Identity=34.5679012345679, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI13376042, Length=324, Percent_Identity=31.1728395061728, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI300863126, Length=376, Percent_Identity=29.7872340425532, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI266458393, Length=200, Percent_Identity=35, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI266458397, Length=200, Percent_Identity=35, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI42794625, Length=200, Percent_Identity=35, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI266456254, Length=200, Percent_Identity=35, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI266458395, Length=143, Percent_Identity=37.7622377622378, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI42822893, Length=143, Percent_Identity=37.7622377622378, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87082093, Length=381, Percent_Identity=99.2125984251969, Blast_Score=788, Evalue=0.0,
Organism=Escherichia coli, GI1788717, Length=401, Percent_Identity=29.925187032419, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1786222, Length=364, Percent_Identity=24.7252747252747, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32564160, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115535051, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648431, Length=333, Percent_Identity=32.1321321321321, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24585488, Length=335, Percent_Identity=28.6567164179104, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 41713; Mature: 41582

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQ
CCCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCH
SLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRPGTMEKLGFSWERLQEIN
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHCC
PRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRVGTSLADLCGGVYL
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCHHCCHHHHHHHHHHH
FSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
HHHHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCCC
VFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKT
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAAEVWLARIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPH
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCEEECCCCEEEECCCCCC
VMPGAATLDQHGEQIRQEFSS
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQ
CCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCH
SLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRPGTMEKLGFSWERLQEIN
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHCC
PRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRVGTSLADLCGGVYL
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCHHCCHHHHHHHHHHH
FSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
HHHHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCCC
VFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKT
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAAEVWLARIHEVGVPVAPLLSVAEAINLPQTQARNMLIEAGGIMMPGNPIKISGCADPH
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCEEECCCCEEEECCCCCC
VMPGAATLDQHGEQIRQEFSS
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]