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The map label for this gene is yihP [H]

Identifier: 170680543

GI number: 170680543

Start: 4360441

End: 4361826

Strand: Reverse

Name: yihP [H]

Synonym: EcSMS35_4262

Alternate gene names: 170680543

Gene position: 4361826-4360441 (Counterclockwise)

Preceding gene: 170679942

Following gene: 170682275

Centisome position: 86.06

GC content: 51.88

Gene sequence:

>1386_bases
ATGAGTCACATCACAACGGAAGATCCAGCAACTTTACGCCTGCCCTTTAAAGAGAAACTCTCTTACGGTATTGGCGACCT
GGCCTCTAACATCCTGCTGGATATTGGTACGCTTTATCTTTTGAAGTTTTATACCGACGTTCTGGGGCTGCCTGGCACCT
ATGGTGGCATTATCTTTTTGATTTCAAAATTCTTTACTGCGTTTACCGATATGGGAACAGGCATCATGCTGGATTCCCGA
CGCAAGATCGGCCCAAAAGGCAAGTTCCGTCCTTTTATTCTGTATGCGTCATTCCCGGTCACCCTGCTGGCGATCGCCAA
CTTTATCGGTACGCCGTTCGATGTCACCGGTAAAACGGTGATGGCCACCATCCTGTTTATGCTTTACGGACTGTTTTTCA
GCATGATGAACTGCTCGTATGGCGCGATGGTCCCCGCTATTACTAAAAACCCCAACGAACGTGCATCGCTGGCAGCATGG
CGTCAGGGTGGCGCTACATTAGGCCTGCTGCTGTGTACGGTGGGATTCGTGCCGGTTATGAATCTTATCGAAGGTAATCA
GCAACTTGGCTATATCTTCGCCGCCACGCTGTTTTCACTGTTCGGCCTGCTGTTTATGTGGATCTGCTACTCGGGCGTGA
AAGAGCGTTATGTCGAAACCCAACCTACCAATCCGGCGCAAAAGCCTGGCTTGTTGCAGTCTTTCCGCGCGATTGCTGGT
AACCGCCCACTGTTCATTCTGTGTATTGCCAACCTCTGCACTTTAGGGGCGTTTAACGTCAAGCTCGCCATTCAGGTCTA
TTACACCCAGTACGTGCTCAACGATCCCATCCTGTTGTCATATATGGGATTTTTCAGCATGGGCTGTATTTTCATCGGCG
TGTTCCTGATGCCCGGCGCAGTCAGACGTTTTGGTAAGAAGAAGGTCTATATCGGCGGCCTGCTGATTTGGGTGCTTGGC
GATCTGCTCAACTATTTCTTTGGCGGCGGTTCGGTCAGCTTCGTGGCGTTCTCCTGCCTGGCATTCTTCGGCTCAGCGTT
TGTTAACAGCCTGAACTGGGCGCTGGTTTCCGACACCGTCGAGTACGGCGAGTGGCGCACCGGTGTGCGTTCGGAAGGTA
CGGTCTACACCGGTTTCACCTTCTTTCGCAAAGTATCTCAGGCGCTGGCAGGTTTCTTCCCAGGCTGGATGCTGACGCAA
ATCGGCTATGTGCCAAACGTCGCCCAGGCTGACCACACTATCGAAGGGTTGCGCCAACTGATCTTCATCTACCCAAGCGC
ACTGGCAGTAGTCACCATCGTGGCAATGGGTTGCTTCTACAGTCTGAACGAGAAGATGTACGTCCGCATTGTTGAAGAGA
TAGAAGCCCGTAAACGCACGGCGTAA

Upstream 100 bases:

>100_bases
TTATCGCGCCGGTAGCGAATGGGCGGCACTGTTCGCCACGTTAAAAAGTATCTAATCATGTCCGCCCGTGGGGAAACTCA
CGGGCAAAGGGAGAACAACG

Downstream 100 bases:

>100_bases
TTATAATAAACAACGCCCTGCGGGGCGTTATAAGGAGTGATTATGTCTGACCATAATCCACTGACATTAAGACTGAATCT
GCGGGAAAAAATCGCCTATG

Product: sugar transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSR
RKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKPGLLQSFRAIAG
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLG
DLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQ
IGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA

Sequences:

>Translated_461_residues
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSR
RKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKPGLLQSFRAIAG
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLG
DLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQ
IGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
>Mature_460_residues
SHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRR
KIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWR
QGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKPGLLQSFRAIAGN
RPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGD
LLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQI
GYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=448, Percent_Identity=24.3303571428571, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI145693206, Length=461, Percent_Identity=99.1323210412148, Blast_Score=929, Evalue=0.0,
Organism=Escherichia coli, GI48994989, Length=456, Percent_Identity=65.1315789473684, Blast_Score=623, Evalue=1e-180,
Organism=Escherichia coli, GI1787902, Length=453, Percent_Identity=33.112582781457, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082306, Length=451, Percent_Identity=29.2682926829268, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786466, Length=420, Percent_Identity=27.6190476190476, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1790561, Length=450, Percent_Identity=26.2222222222222, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50997; Mature: 50866

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00872 NA_GALACTOSIDE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFL
CCCCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTV
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHH
MATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGLLLCTVGFVPVM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
NLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKPGLLQSFRAIAG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHC
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGA
CCCEEEHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
VRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTV
HHHHCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQADHTIEGLRQL
HHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHH
IFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFL
CCCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTV
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHH
MATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGLLLCTVGFVPVM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
NLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKPGLLQSFRAIAG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHC
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGA
CCCEEEHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHH
VRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTV
HHHHCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQADHTIEGLRQL
HHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHH
IFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]