BacMap

Definition	Escherichia coli SMS-3-5 chromosome, complete genome.
Accession	NC_010498
Length	5,068,389

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The map label for this gene is ygcW [H]

Identifier: 170680420

GI number: 170680420

Start: 2973387

End: 2974172

Strand: Reverse

Name: ygcW [H]

Synonym: EcSMS35_2902

Alternate gene names: 170680420

Gene position: 2974172-2973387 (Counterclockwise)

Preceding gene: 170682101

Following gene: 170679795

Centisome position: 58.68

GC content: 45.29

Gene sequence:

>786_bases
ATGTCAATCGAATCTCTCAATGCGTTCTCAATGGATTTTTTCTCCCTGAAAGGTAAAACAGCAATTGTTACCGGCGGGAA
TAGCGGTTTAGGCCAGGCATTTGCCATGGCGTTGGCCAAAGCTGGCGCAAATGTCTTTATCCCTAGCTTCGTCAAAGATA
ACGGCGAAACAAAGGAAATGATTGAAAAACAGGGTGTCGAAGTTGATTTTATGCAGGTGGATATCACCGCAGAAGGCGCG
CCGCAGAAGATTATCGCTGCCTGCTGTGAGCGCTTCGGTACCGTAGATATTCTGGTTAACAATGCCGGTATTTGTAAGCT
GAATAAGGTGCTGGACTTTGGTCGTGCCGACTGGGACCCGATGATTGACGTGAACCTGACCGCCGCATTCGAGTTAAGCT
ATGAAGCTGCAAAAATTATGATCCCGCAGAAAAGCGGTAAAATCATTAATATCTGTTCATTATTCTCTTACTTAGGTGGA
CAATGGTCACCTGCATATTCTGCCACTAAACATGCTCTTGCCGGATTCACCAAAGCTTATTGTGATGAACTAGGTCAATA
TAATATTCAGGTAAATGGTATTGCCCCTGGATATTACGCTACCGATATCACCCTGGCGACACGCAGTAATCCAGAAACCA
ATCAGCGCGTTCTTGATCATATTCCAGCAAACCGTTGGGGCGATACTCAGGATTTAATGGGCACAGCCATATTTCTCGCA
AGTCCGGCATCGAATTATGTCAACGGACATTTATTAGTGGTTGATGGCGGTTATTTAGTGCGCTAA

Upstream 100 bases:

>100_bases
AAAATTATCTCCAGTTACCAGAGATAATGAGAAAGGTAACTTCCCTCTCGCGGGGGAAGTTACCTTTCTTTTTTTTGCTT
TACGGAAATTGGAGTTAACT

Downstream 100 bases:

>100_bases
TCCATAACGGTGGTTTCTGTTTTCTCTTATTAATGATTATTCCATTTTTATTATCAGGAAGGAATTACTATGTCTTTATC
TCGCGCAGCGATTGTCGACC

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGA
PQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGTAIFLA
SPASNYVNGHLLVVDGGYLVR

Sequences:

>Translated_261_residues
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGA
PQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGTAIFLA
SPASNYVNGHLLVVDGGYLVR
>Mature_260_residues
SIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAP
QKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQ
WSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGTAIFLAS
PASNYVNGHLLVVDGGYLVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=30, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=28.9156626506024, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=30.3030303030303, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=27.0161290322581, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=29.4354838709677, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=30.859375, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI31542939, Length=220, Percent_Identity=29.5454545454545, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=26, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=29.2079207920792, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=30, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=28.82096069869, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI83715985, Length=182, Percent_Identity=32.4175824175824, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=25.6, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=26.6129032258064, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7657478, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=98.4674329501916, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=43.6, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=39.6, Blast_Score=190, Evalue=8e-50,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.4677419354839, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=34.136546184739, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=34.8, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.90625, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=28.1124497991968, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=26.9076305220884, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=29.1497975708502, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=28.6259541984733, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=25.7894736842105, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=32.6530612244898, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=30.6772908366534, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=33.1983805668016, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=31.7460317460317, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=33.203125, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=30.241935483871, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.6290322580645, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.4832713754647, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=31.1787072243346, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=30.7116104868914, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=25.9109311740891, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=30.4832713754647, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=29.5019157088123, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=30, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=257, Percent_Identity=27.2373540856031, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=27.9693486590038, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=28.6821705426357, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=28.1853281853282, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=30.5343511450382, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=31.0526315789474, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=25.9541984732824, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=31.0077519379845, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=25.2, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=28.7958115183246, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=201, Percent_Identity=28.8557213930348, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=24.8, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=25.6916996047431, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=27.2, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557668, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=24.7368421052632, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559552, Length=205, Percent_Identity=30.7317073170732, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=238, Percent_Identity=28.1512605042017, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=258, Percent_Identity=22.8682170542636, Blast_Score=64, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI32563809, Length=258, Percent_Identity=22.8682170542636, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=32.2916666666667, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=26.7716535433071, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=208, Percent_Identity=27.4038461538462, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.4516129032258, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=32.9365079365079, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.3886639676113, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.9236947791165, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=30.1587301587302, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=28.5140562248996, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=32.3076923076923, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=27.1356783919598, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649181, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640442, Length=217, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=25.6544502617801, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28130; Mature: 27999

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEM
CCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEECHHHCCCCCHHHH
IEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDP
HHHCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHCCCCCCCC
MIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAY
EEEEEEEEEEEEEECEEEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
CDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGTAIFLA
HHHHCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHEEEEEE
SPASNYVNGHLLVVDGGYLVR
CCCCCCCCCEEEEEECCEEEC
>Mature Secondary Structure 
SIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEM
CCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEECHHHCCCCCHHHH
IEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDP
HHHCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHCCCCCCCC
MIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAY
EEEEEEEEEEEEEECEEEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
CDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGTAIFLA
HHHHCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHEEEEEE
SPASNYVNGHLLVVDGGYLVR
CCCCCCCCCEEEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9205837 [H]