Click here to switch to the map view.

The map label for this gene is glpX2 [H]

Identifier: 170680034

GI number: 170680034

Start: 3160195

End: 3161160

Strand: Reverse

Name: glpX2 [H]

Synonym: EcSMS35_3072

Alternate gene names: 170680034

Gene position: 3161160-3160195 (Counterclockwise)

Preceding gene: 170683729

Following gene: 170679690

Centisome position: 62.37

GC content: 56.31

Gene sequence:

>966_bases
ATGATGTCCCTGGCGTGGCCATTATTTCGCGTTACGGAACAGGCAGCGTTGGCTGCCTGGCCGCAAACCGGATGTGGCGA
CAAAAATAAAATTGATGGCCTGGCGGTCACCGCGATGCGCCAGGCATTAAACGACGTCGCTTTTCGTGGGCGAGTGGTTA
TCGGCGAGGGAGAGATTGACCATGCGCCGATGCTGTGGATTGGCGAAGAGGTGGGCAAAGGCGATGGGCCAGAAGTCGAT
ATCGCGGTTGATCCCATTGAAGGTACGCGGATGGTGGCGATGGGGCAGAGCAATGCGCTGGCGGTCATGGCTTTCGCACC
TCGGGATAGCCTGTTACATGCGCCCGATATGTATATGAAAAAGCTGGTTGTTAATCGACAGGCTGCCGGGGCGATTGATC
TGTCTTTGCCTCTGGCGGACAACTTGCGAAACGTGGCGAAAGCGTTAGGCAAACCGCTGGACAAACTGCGCATGGTTACG
CTGGATAAACCGCGCCTGAGTACCGCAATTGAGGAAGCAACACAGCTGGGCGTGAAGGTTTTTGCCCTGCCGGATGGCGA
TGTCGCCGCCAGCGTGCTGACCTGCTGGCAGGATAATCCTTACGATGTGATGTACACCATCGGCGGTGCGCCGGAGGGCG
TGATTTCTGCCTGTGCCGTTAAAGCATTAGGCGGGGATATGCAGGCCGAGCTGATTGACTTTTGTCAGGCTAAAGGGGAT
TACACGGAAAATCGGCAGATTGCAGAGCAGGAGCGCAAGCGTTGCAAGGAAATGGGCGTTGACGTTAACCGTGTGTACTC
GCTCGATGAACTGGTGAGGGGGAACGATATCCTCTTTAGCGCTACGGGCGTGACGGGCGGCGAGTTGGTGAACGGTATCC
AACAGACGGCGAATGGGGTGCGGACGCAGACATTACTGATCGGCGGCGCGGACCAAACGTGTAATATAATAGACTCCCTG
CATTGA

Upstream 100 bases:

>100_bases
AACTGGCGCGGCTGGTTGAGGAAACGCACGGTATCTGGAATGAACAGGCCGAGAAATATCTGCTGGCGCAATTTGGCGTT
GATATTGGGGAGGCCGCGCA

Downstream 100 bases:

>100_bases
TGGTGATCTATCGGAAGACCAATGGCGACGCTGACAGAAGATGATGTGCTTGAGCAACTGGAGGCACAGGACAATTTATT
TTCATTTATGAAAACGGCGC

Product: fructose-1,6-bisphosphatase II-like protein

Products: NA

Alternate protein names: FBPase 2 class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 class 2 [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALNDVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVD
IAVDPIEGTRMVAMGQSNALAVMAFAPRDSLLHAPDMYMKKLVVNRQAAGAIDLSLPLADNLRNVAKALGKPLDKLRMVT
LDKPRLSTAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISACAVKALGGDMQAELIDFCQAKGD
YTENRQIAEQERKRCKEMGVDVNRVYSLDELVRGNDILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSL
H

Sequences:

>Translated_321_residues
MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALNDVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVD
IAVDPIEGTRMVAMGQSNALAVMAFAPRDSLLHAPDMYMKKLVVNRQAAGAIDLSLPLADNLRNVAKALGKPLDKLRMVT
LDKPRLSTAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISACAVKALGGDMQAELIDFCQAKGD
YTENRQIAEQERKRCKEMGVDVNRVYSLDELVRGNDILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSL
H
>Mature_321_residues
MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALNDVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVD
IAVDPIEGTRMVAMGQSNALAVMAFAPRDSLLHAPDMYMKKLVVNRQAAGAIDLSLPLADNLRNVAKALGKPLDKLRMVT
LDKPRLSTAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISACAVKALGGDMQAELIDFCQAKGD
YTENRQIAEQERKRCKEMGVDVNRVYSLDELVRGNDILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSL
H

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Also displays a low activity toward glucose 1,6-bisphosphate, and no activity against ribulose 1,5- bisphosphate, fructose 2,6-bisphosphate, or fructose 1-phosphate [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1789298, Length=321, Percent_Identity=98.7538940809969, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1790360, Length=318, Percent_Identity=57.8616352201258, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34397; Mature: 34397

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALNDVAFRGRVVIGEGEID
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCC
HAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAVMAFAPRDSLLHAPDMYMK
CCCEEEECHHHCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHH
KLVVNRQAAGAIDLSLPLADNLRNVAKALGKPLDKLRMVTLDKPRLSTAIEEATQLGVKV
HHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHEEEECCCCHHHHHHHHHHHCCEEE
FALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISACAVKALGGDMQAELIDFCQAKGD
EEECCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
YTENRQIAEQERKRCKEMGVDVNRVYSLDELVRGNDILFSATGVTGGELVNGIQQTANGV
CCCCHHHHHHHHHHHHHHCCCHHHHHCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCC
RTQTLLIGGADQTCNIIDSLH
EEEEEEEECCCCHHHHHHCCC
>Mature Secondary Structure
MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALNDVAFRGRVVIGEGEID
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCC
HAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAVMAFAPRDSLLHAPDMYMK
CCCEEEECHHHCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHH
KLVVNRQAAGAIDLSLPLADNLRNVAKALGKPLDKLRMVTLDKPRLSTAIEEATQLGVKV
HHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHEEEECCCCHHHHHHHHHHHCCEEE
FALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISACAVKALGGDMQAELIDFCQAKGD
EEECCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
YTENRQIAEQERKRCKEMGVDVNRVYSLDELVRGNDILFSATGVTGGELVNGIQQTANGV
CCCCHHHHHHHHHHHHHHCCCHHHHHCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCC
RTQTLLIGGADQTCNIIDSLH
EEEEEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2546007 [H]